Results 31 to 40 of about 827,746 (374)

Suicide‐specific mortality among patients with treatment‐resistant major depressive disorder, major depressive disorder with prior suicidal ideation or suicide attempts, or major depressive disorder alone

Brain and Behavior, 2023
Background The impact of treatment‐resistant depression (TRD) or prior suicidal ideation/suicide attempt (SI/SA) on mortality by suicide among patients with major depressive disorder (MDD) is not well known. This retrospective, observational, descriptive
David M. Kern, Carla M. Canuso, Ella Daly, Jonathan C. Johnson, Dong Jing Fu, Teodora Doherty, Cori Blauer‐Peterson, M. Soledad Cepeda   +7 more
doaj   +1 more source

Major depressive disorder in detention officers

Revista de Saúde Pública, 2021
OBJECTIVE To identify factors associated with major depressive disorder (MDD) in detention officers. METHODS This cross-sectional study included all detention officers from the largest prison complex in the state of Bahia, Brazil.
Sheila Nascimento Santos, Kionna Oliveira Bernardes Santos, Fernando Martins Carvalho, Rita de Cássia Pereira Fernandes   +3 more
doaj   +2 more sources

Glutamate and GABA Homeostasis and Neurometabolism in Major Depressive Disorder

Frontiers in Psychiatry, 2021
Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As per the latest WHO report, MDD affects more than 260 million people worldwide.
Ajay Sarawagi, N. Soni, A. Patel
semanticscholar   +1 more source

Major depressive disorder [PDF]

, 2007
Depression in its various forms is a commonly seen disorder in general practice. Indeed, over 90% of patients suffering from depression are seen, diagnosed and treated in primal) care.
Bonello, Arlene
core   +1 more source

Sub-threshold depressive symptoms and brain structure: A magnetic resonance imaging study within the Whitehall II cohort [PDF]

, 2016
BACKGROUND: Late-life sub-threshold depressive symptoms (i.e. depressive symptoms that do not meet the criteria for a diagnosis of major depressive disorder) are associated with impaired physical health and function, and increased risk of major ...
Allan, CL, Ebmeier, KP, Filippini, N, Kivimaki, M, Mackay, CE, Mahmood, A, Sexton, CE, Shipley, MJ, Singh-Manoux, A, Topiwala, A, Zsoldos, E   +10 more
core   +4 more sources

Genetic evidence suggests posttraumatic stress disorder as a subtype of major depressive disorder

Journal of Clinical Investigation, 2021
BACKGROUND Major depressive disorder (MDD) and posttraumatic stress disorder (PTSD) are highly comorbid and exhibit strong correlations with one another.
Fuquan Zhang, Shuquan Rao, Hongbao Cao, Xiangrong Zhang, Qiang Wang, Yong Xu, Jing Sun, Chun Wang, Jiu Chen, Xijia Xu, Ning Zhang, Lin Tian, Jianmin Yuan, Guoqiang Wang, Lei Cai, Mingqing Xu, A. Baranova   +16 more
semanticscholar   +1 more source

What patients with bipolar disorder and major depressive disorder perceive as adverse life events precipitating a current major depressive episode

South African Journal of Psychiatry, 2015
Background. Adverse life events (ALEs) as precipitants of a major depressive episode (MDE) have been the subject of many studies. These studies indicate an increase in ALEs in the 6 months preceding an MDE. Objectives.
Robyn Anne van Schoor, Pierre M Joubert
doaj   +1 more source

Brain aging in major depressive disorder

European Psychiatry, 2021
Depression and anxiety are common and often comorbid mental health disorders that represent risk factors for aging-related conditions. Brain aging has shown to be more advanced in patients with Major Depressive Disorder (MDD).
L. Han, H. Schnack, R. Brouwer, D. Veltman, N. Van Der Wee, M.-J. Van Tol, M. Aghajani, B. Penninx   +7 more
doaj   +1 more source

A mega-Analysis of genome-wide association studies for major depressive disorder [PDF]

, 2013
Prior genome-wide association studies (GWAS) of major depressive disorder (MDD) have met with limited success. We sought to increase statistical power to detect disease loci by conducting a GWAS mega-analysis for MDD.
Lin, Danyu, Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium   +1 more
core   +2 more sources

Bidirectional Association between Major Depressive Disorder and Gastroesophageal Reflux Disease:Mendelian Randomization Study [PDF]

, 2022
Background: Observational research has found a bidirectional relationship between major depressive disorder and gastroesophageal reflux disease; however, the causal association of this relationship is undetermined.
Chen, Jie, Larsson, Susanna C, Li, Xue, Li, Ye, Miao, Yuyang, Yuan, Shuai, Zhang, Qiang   +6 more
core   +1 more source