Results 31 to 40 of about 832,143 (393)

Failure of hippocampal deactivation during loss events in treatment-resistant depression [PDF]

, 2015
Major depressive disorder is characterized by anhedonia, cognitive biases, ruminations, hopelessness and increased anxiety. Blunted responses to rewards have been reported in a number of recent neuroimaging and behavioural studies of major depressive ...
Blair A. Johnston, Cavanagh, David Christmas, J. Douglas Steele, Keith Matthews, Ma, Serenella Tolomeo, Victoria Gradin, Zhang   +8 more
core   +2 more sources

Glutamate and GABA Homeostasis and Neurometabolism in Major Depressive Disorder

Frontiers in Psychiatry, 2021
Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As per the latest WHO report, MDD affects more than 260 million people worldwide.
Ajay Sarawagi, N. Soni, A. Patel
semanticscholar   +1 more source

Comorbid depressive disorders in ADHD. the role of ADHD severity, subtypes and familial psychiatric disorders [PDF]

, 2014
ObjectiveaaTo evaluate the presence of Major Depressive Disorder (MDD) and Dysthymic Disorder (DD) in a sample of Italian children with Attention Deficit Hyperactivity Disorder (ADHD) and to explore specific features of comorbid depressive disorders in ...
Andriola E, Di Roma F, DI TRANI, MICHELA, Donfrancesco R., Leone D, Miano S, PARISI, Pasquale   +6 more
core   +1 more source

What patients with bipolar disorder and major depressive disorder perceive as adverse life events precipitating a current major depressive episode

South African Journal of Psychiatry, 2015
Background. Adverse life events (ALEs) as precipitants of a major depressive episode (MDE) have been the subject of many studies. These studies indicate an increase in ALEs in the 6 months preceding an MDE. Objectives.
Robyn Anne van Schoor, Pierre M Joubert
doaj   +1 more source

Sensor-AssistedWeighted Average Ensemble Model for Detecting Major Depressive Disorder [PDF]

, 2019
The present methods of diagnosing depression are entirely dependent on self-report ratings or clinical interviews. Those traditional methods are subjective, where the individual may or may not be answering genuinely to questions.
Chang, Chuan-Yu, Gao, Liang, Garg, Akhil, Gutiérrez Reina, Daniel, Mahendran, Nivedhitha, Srinivasan, Kathiravan, Vincent, Durai Raj   +6 more
core   +1 more source

Do Suicide Attempts of Mood Disorder Patients Directly Increase the Risk for a Reattempt?

Frontiers in Psychiatry, 2020
Background: Preceding suicide attempts strongly predict future suicidal acts. However, whether attempting suicide per se increases the risk remains undetermined.
Kari I. Aaltonen, Kari I. Aaltonen, Tom Rosenström, Tom Rosenström, Pekka Jylhä, Pekka Jylhä, Irina Holma, Irina Holma, Mikael Holma, Mikael Holma, Sanna Pallaskorpi, Sanna Pallaskorpi, Kirsi Riihimäki, Kirsi Suominen, Maria Vuorilehto, Maria Vuorilehto, Erkki T. Isometsä, Erkki T. Isometsä   +17 more
doaj   +1 more source

Prevalence and correlates of depressive disorders in people with Type 2 diabetes: results from the International Prevalence and Treatment of Diabetes and Depression (INTERPRET‐DD) study, a collaborative study carried out in 14 countries [PDF]

, 2018
Aims To assess the prevalence and management of depressive disorders in people with Type 2 diabetes in different countries. Methods People with diabetes aged 18–65 years and treated in outpatient settings were recruited in 14 countries and underwent
Ahmed, H. U., Alvarez, A., Bahendeka, S., Basangwa, D., Boborov, A. E., Boden, S., Bulgari, V., Burti, L., Chaturvedi, S. K., Cimino, L. C., de Girolamo, G., Gaebel, W., Gondek, T. M., Guinzbourg de Braude, M., Guntupalli, A., Heinze, M. G., Hong, X., Ji, L., Kamala, T., Khan, A., Kiejna, A., Kokoszka, A., Lalic, N. M., Lecic Tosevski, D., Li, M., Lloyd, C. E., Mankovsky, B., Musau, A., Mussig, K., Ndetei, D., Nouwen, A., Rabbani, G., Sartorius, N., Shevchuk, M., Srikanta, S. S., Starostina, E. G., Taj, R., Vukovic, O., Wolwer, W., Xin, Y.   +39 more
core   +2 more sources

A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression.

PLoS Genetics, 2019
Major depression is a common and severe psychiatric disorder with a highly polygenic genetic architecture. Genome-wide association studies have successfully identified multiple independent genetic loci that harbour variants associated with major ...
Zachary F Gerring, Eric R Gamazon, Eske M Derks, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium   +3 more
doaj   +1 more source

Serum level of soluble interleukin 6 receptor is a useful biomarker for identification of treatment‐resistant major depressive disorder

Neuropsychopharmacology Reports, 2020
Aim A substantial proportion of major depressive disorder patients are treatment‐resistant to antidepressant therapy, who require augmentation drugs, or other treatments including electroconvulsive therapy or transcranial magnetic stimulation ...
Katsuhiko Yamasaki, Tomonori Hasegawa, Masatoshi Takeda   +2 more
doaj   +1 more source

Patient-reported outcomes in major depressive disorder with suicidal ideation: a real-world data analysis using PatientsLikeMe platform

BMC Psychiatry, 2020
Background The current analysis utilized data collected via an online patient community platform, PatientsLikeMe (PLM) to compare patient-reported experiences in patients with major depressive disorder (MDD) with suicidal ideation (MDSI) to those with ...
Stephane Borentain, Abigail I. Nash, Rachna Dayal, Allitia DiBernardo   +3 more
doaj   +1 more source