The porcine Major Histocompatibility Complex and related paralogous regions: a review
Genetics Selection Evolution, 2000 The physical alignment of the entire region of the pig major histocompatibility complex (MHC) has been almost completed. In swine, the MHC is called the SLA (swine leukocyte antigen) and most of its class I region has been sequenced.
Vaiman Marcel +3 more
doaj +1 more source
Structure of a Complex of the Human α/β T Cell Receptor (TCR) HA1.7, Influenza Hemagglutinin Peptide, and Major Histocompatibility Complex Class II Molecule, HLA-DR4 (DRA0101 and DRB10401) [PDF]
, 2002 Jens Hennecke, Don C. Wiley
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T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex [PDF]
, 2015 Central to adaptive immunity is the interaction between the αβ T cell receptor (TCR) and peptide presented by the major histocompatibility complex (MHC) molecule.
Beringer, Dennis X. +22 more
core +1 more source
Advanced Science, EarlyView.Integrating hierarchical physicochemical features via a bio‐inspired design, the DAISY framework robustly predicts T‐cell receptor binding, significantly outperforming state‐of‐the‐art models on unseen epitopes. It uniquely offers visual interpretability via Score‐CAM visualizations and profound clinical relevance, correlating with T‐cell expansion ...
Yajing Yuan +9 more
wiley +1 more source
Identification of a CD4+ T cell-stimulating antigen of pathogenic bacteria by expression cloning. [PDF]
, 1995 Identifying the immunogenic proteins that elicit pathogen-specific T cell responses is key to rational vaccine design. While several approaches have succeeded in identifying major histocompatibility complex (MHC) class I bound peptides that stimulate CD8+
Campbell, D +2 more
core +1 more source
Advanced Science, EarlyView.In this study, a multifunctional iron‐copper metal–organic framework nanozyme platform co‐delivering chloroquine and perfluorohexane is engineered to circumvent tumor immune evasion by disrupting autophagic flux and restoring major histocompatibility complex class I presentation. This dual‐action nanoplatform orchestrates synergistic autophagy blockade
Li Yan +8 more
wiley +1 more source
Genomic organization of duplicated major histocompatibility complex class I regions in Atlantic salmon (Salmo salar) [PDF]
, 2007 Morten Lukacs +10 more
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Marginal Stability of the YB1 Cold‐Shock Domain in Cells Enables Binding of Multiple Nucleic Acids
Advanced Science, EarlyView.This study suggests that the marginal stability of the YB1 Cold‐Shock Domain (CSDex) allows for a balance between multifunctionality and conformational changes under physiological conditions. This balance is driven by the dynamic equilibrium between the unfolded ensemble (UE) and the native ensemble (NE) of CSDex (PDB:6LMR).
Puja Shrestha +4 more
wiley +1 more source
Characterization of Major Histocompatibility Complex Genes in Jungle Fowls, Genus Gallus
The Journal of Poultry Science, 2003 Chicken major histocompatibility complex (Mhc) is smaller in size and contains fewer genes than does mammal Mhc. To clarify the characters of Mhc genes in junglefowls as the ancestral species of domestic chickens, we analyzed their Mhc class I B-F and ...
Masahide Nishibori +2 more
doaj +1 more source
Major Histocompatibility Complex Variation and Haplotype Associated Survival in Response to Experimental Infection of Two Bd-GPL Strains Along a Latitudinal Gradient [PDF]
, 2022 Maria Cortázar‐Chinarro +6 more
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