Secretion of mediators following T lymphocyte-macrophage interaction is regulated by the major histocompatibility complex. [PDF]
Andrew G. Farr, M E Dorf, Emil R. Unanue
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This review summarizes recent advances in the spatiotemporal dynamics of the tumor microenvironment (TME). It highlights the roles of diverse immune and stromal cell populations, spatial architecture of the TME, as well as the gut and tumor microbiota in influencing responses to immune checkpoint inhibitors (ICIs), by integrating insights from single ...
Yuanyuan Zhang, Zhihua Liu
wiley +1 more source
Genetic Differences in BCG-Induced Resistance to Schistosoma Mansoni Are not Controlled by Genes within the Major Histocompatibility Complex of the Mouse [PDF]
Richard Civil, Adel A. F. Mahmoud
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Expression of natural killer receptor alleles at different Ly49 loci occurs independently and is regulated by major histocompatibility complex class I molecules. [PDF]
Ly49 receptor genes are expressed by subsets of natural killer (NK) cells in an overlapping fashion, accounting for the capacity of NK subsets to attack host cells that have selectively downregulated self-major histocompatibility complex (MHC) class I ...
Hanke, T+4 more
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IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang+15 more
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The role of subregions of the rat major histocompatibility complex in the rejection and passive enhancement of renal allografts. [PDF]
GEORGE GREGORY GALLICO+2 more
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Differential detection of impact site versus rotational site injury by magnetic resonance imaging and microglial morphology in an unrestrained mild closed head injury model. [PDF]
Seventy-five percent of all traumatic brain injuries are mild and do not cause readily visible abnormalities on routine medical imaging making it difficult to predict which individuals will develop unwanted clinical sequelae. Microglia are brain-resident
Carson, Monica J+4 more
core
Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu+7 more
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Control of mating preferences in mice by genes in the major histocompatibility complex.
K Yamazaki+8 more
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This study develops the hydrogel with antimicrobial, adhesive, degradable, injectable, and temperature‐sensitive contraction properties based on the transcriptomic and pathological characteristics of intestinal fistula patients. This hydrogel can seal rabbit intestinal fistula in situ, reduce the intestinal defect, and promote intestinal epithelial ...
Ze Li+12 more
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