Results 171 to 180 of about 680,011 (354)

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

Arthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Lymphoid Organ Size Varies Among Inbred Lines 63 and 72 and Their Thirteen Recombinant Congenic Strains of Chickens with the Same Major Histocompatibility Complex

, 2006
H.M. Zhang, Henry D. Hunt, GB Kulkarni, Debra E. Palmquist, L D Bacon   +4 more
openalex   +1 more source

Association between Genes of the Major Histocompatibility Complex Class II and the Outcome of Hepatitis C Virus Infection [PDF]

, 1999
Laurent Alric, Marylise Fort, Jacques Izopet, Jean‐Pierre Vinel, M Duffaut, M. Abbal   +5 more
openalex   +1 more source

Linking Skin and Joint Inflammation in Psoriatic Arthritis through Shared CD8+ T Cell Clones

Arthritis &Rheumatology, EarlyView.
Objective Psoriatic arthritis (PsA) is an HLA class I–associated inflammatory arthritis that develops in up to 30% of people with psoriasis. We tested the hypothesis that skin and joint inflammation in PsA is linked in terms of CD8+ T cell phenotype and clonality.
Lucy E. Durham, Frances Humby, Nora Ng, Roman Laddach, Elizabeth H. Gray, Sarah E. Ryan, Kathryn J. A. Steel, Rosie Ross, Giovanni A. M. Povoleri, Rosamond Nuamah, Kathy Fung, Athul Menon Kallayil, Pawan Dhami, Bruce W. Kirkham, Leonie S. Taams   +14 more
wiley   +1 more source

A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus. [PDF]

, 1994
Craig M. Story, J Mikulska, Neil E. Simister   +2 more
openalex   +1 more source

A Tolerogenic Plasmid Inhibits Autoantibody Production Triggered by Immunization With Human Peptidyl Arginine Deiminase 4

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is usually preceded and likely mediated by autoantibodies to citrullinated proteins (ACPAs) that recognize citrulline residues on multiple proteins. Conversion of arginine into citrulline is performed by enzymes called peptidyl arginine deiminases (PADs). We have previously demonstrated that the human PAD4 (hPAD4) is
Philippe P. Pagni, Vijetha Kumar, Nathalie C. Lambert, Eva Frison, Herve Luche, Marielle Mello, Magali Torres, Johnna D. Wesley, Matthias von Herrath, Jean Roudier, Isabelle Auger   +10 more
wiley   +1 more source

Modulation of Ly49A+ Natural Killer Cell Licensing by Major Histocompatibility Complex Class I Alleles

, 2012
A. Helena Jonsson
openalex   +2 more sources

Comparative Effectiveness of Abatacept Versus Adalimumab in Shared Epitope Positive and Negative Patients With Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective The effect of the shared epitope (SE) and valine at position 11 (Val11) of HLA–DRB1 on the activation of CD4+ T cells is expected to be diminished by abatacept, a costimulation blocker. However, published evidence on the value of genetic stratification for abatacept treatment is conflicting. We aimed to compare the difference in effectiveness
Chuan Fu Yap, Nisha Nair, Seema D. Sharma, John Bowes, Amirah Binti Mohammad Ariff, Ann W. Morgan, John D. Isaacs, Anthony G. Wilson, Kimme L. Hyrich, Suzan Verstappen, James Bluett, Andrew P. Morris, Anne Barton, Darren Plant, Sebastien Viatte   +14 more
wiley   +1 more source

High Viremia Is Associated with High Levels of In Vivo Major Histocompatibility Complex Class I Downregulation in Rhesus Macaques Infected with Simian Immunodeficiency Virus SIVmac239 [PDF]

, 2010
Thomas C. Friedrich, Shari M. Piaskowski, Enrique J. León, Jessica Furlott, Nicholas J. Maness, Kimberly L. Weisgrau, Caitlin E. Mac Nair, Andrea M. Weiler, John T. Loffredo, Matthew R. Reynolds, Ken Williams, Yann C. Klimentidis, Nancy A. Wilson, David B. Allison, Eva G. Rakasz   +14 more
openalex   +1 more source

Is there a link between economic outcomes and genetic evolution? Cross-country evidence from the major histocompatibility complex [PDF]

This research develops a theory and presents empirical evidence of a link between economicoutcomes and genetic evolution. Important properties for successful analysis of such a link arefound in the adaptive immune system and particularly in the major ...
Borghans,José, Borghans,Lex, Weel,Bas,ter   +2 more
core   +1 more source