Comparison of antigen specificity, class II major histocompatibility complex restriction, and in vivo behavior of myelin basic protein-specific T cell lines and clones derived from (BALB/c x SJL/J) mice. [PDF]
, 1987 Joseph Trotter +2 more
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Arthritis &Rheumatology, Accepted Article.Objectives The effect of the shared epitope (SE), and valine at position 11 (Val11) of HLA‐DRB1, on the activation of CD4+ T cells, is expected to be diminished by abatacept, a co‐stimulation blocker. However, published evidence on the value of genetic stratification for abatacept treatment is conflicting.
Chuan Fu Yap +14 more
wiley +1 more source
Suppression of Ia-unrestricted primary anti-Qa-1 cytotoxic T lymphocyte responses by class II major histocompatibility complex-restricted cellular interactions. [PDF]
, 1987 David P. Huston, Ghamartaj Tavana
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B cells and systemic sclerosis interstitial lung disease
Arthritis &Rheumatology, Accepted Article.Interstitial lung disease is an important complication of systemic sclerosis (SSc‐ILD) with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to FDA‐approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of interstitial lung diseases of other systemic autoimmune ...
Nina Goldman +2 more
wiley +1 more source
Biofuels, Bioproducts and Biorefining, EarlyView.Abstract The sustainable production of jojoba oil derivatives depends on research and development focused on eco‐friendly valorization processes. This study establishes optimal conditions for converting jojoba oil into jojobyl alcohols, which is a key step in realizing its economic potential.
Laura Mendoza‐García +3 more
wiley +1 more source
Monoclonal antibodies to mouse MHC antigens. II. Antibodies to the H-2Ld antigen, the products of a third polymorphic locus of the mouse major histocompatibility complex. [PDF]
, 1980 Keiko Ozato, T H Hansen, David H. Sachs
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Host Cell Protein Clinical Safety Risk Assessment—An Updated Industry Review
Biotechnology and Bioengineering, EarlyView.ABSTRACT Host cell proteins (HCP) are process‐related impurities that can co‐purify with therapeutic proteins. Some HCP impurities potentially can have an impact on patient safety (immunogenicity or toxicity), efficacy, and/or product quality. It is important to reduce the levels of HCP impurities with a well‐controlled manufacturing process and to ...
Lisette Coye +19 more
wiley +1 more source
The Amphibian Major Histocompatibility Complex-A Review and Future Outlook. [PDF]
J Mol EvolSabino-Pinto J, Maan ME.
europepmc +1 more source
Differential cellular immune responsiveness to systems of the major histocompatibility complex
, 1976 Fritz H. Bach
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Cytotoxic interaction of virus specific effector cells with virus infected targets of different cell type [PDF]
, 1977 Ertl, Hildegund, Koszinowski, Ulrich H.
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