Results 181 to 190 of about 133,059 (255)

Case Report: Atypical extensive orbitofacial tuberculosis extending to the skull base and cavernous sinus revealed major histocompatibility complex class II deficiency in an 11-year-old girl. [PDF]

Front Pediatr
Mezri S, Amri A, Essghaier S, Tlili K, Rabhi M, Marmouri M, Barakizou H.   +6 more
europepmc   +1 more source

Impact of G‐CSF on Donor TCR Clonal Diversity and T Cell Function During Donor HSC Mobilisation

Cell Proliferation, EarlyView.
In this study, we found that G‐CSF mobilisation caused a reduction in TCR clonal diversity and down‐regulation of T‐cell function in donors. This may be one of the reasons for the low incidence of GVHD mediated by G‐CSF after allo‐HSCT. Source: Created in BioRender. Li https://BioRender.com/otownki.
Xinye Li, Zhixi Chen, Jie Chen, Xingwei Zhang, Jiamian Zheng, Zirui Liu, Meixue Pan, Yue Li, Bo Yu, Shaohua Chen, Jing Lai, Xianfeng Zha, Liye Zhong, Yikai Zhang, Yangqiu Li   +14 more
wiley   +1 more source

pMHChat, characterizing the interactions between major histocompatibility complex class II molecules and peptides with large language models and deep hypergraph learning. [PDF]

Brief Bioinform
Ma J, Wang Z, Tong C, Yang Q, Zhang L, Liu H.   +5 more
europepmc   +1 more source

A Multicellular Coordinated Network Driving Lymphovascular Space Invasion in Endometrioid Endometrial Carcinoma

Cell Proliferation, EarlyView.
Single‐cell and spatial profiling reveal that lymphovascular space invasion in endometrioid endometrial carcinoma is driven by coordinated interactions among metastatic epithelium, fibroblasts, immune cells, and endothelium. This multicellular network promotes matrix remodelling, angiogenesis, and immune evasion, forming a pro‐metastatic niche that ...
Wendi Guo, Tianxiang Liu, Runling Ren, Na Li, Wenwen Zhang, Jingwen Si, Yongjun Piao, Yuanjing Hu   +7 more
wiley   +1 more source

Female-mediated selective sperm activation may remodel major histocompatibility complex-based mate choice decisions in humans. [PDF]

Heredity (Edinb)
Jokiniemi A, Turunen T, Kohonen M, Magris M, Ritari J, Kuusipalo L, Partanen J, Kekäläinen J.   +7 more
europepmc   +1 more source

Polymorphic myopathological findings in a 77‐year‐old woman with oculo‐bulbo‐facial and distal weakness

Brain Pathology, EarlyView.
Michele Tosi, Angela Puma, Elena Faedo, Gianmarco Severa, Luisa Villa, Sabrina Sacconi, Edoardo Malfatti   +6 more
wiley   +1 more source

Integrated Engineering of CAR‐T Cells for Solid Tumours

Cell Proliferation, EarlyView.
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang, Tan Li, Ping He, Zhijie Zhao, Shenglong Li, Liming Wang   +5 more
wiley   +1 more source

Palaeognaths Reveal Evolutionary Ancestry of the Avian Major Histocompatibility Complex Class II. [PDF]

Genome Biol Evol
Minias P, Babik W.
europepmc   +1 more source

Regulation of major histocompatibility complex class-I (MHC-I) gene methylation using DNA methyltransferase inhibitor and PD-L1 inhibitor in triple negative breast cancer. [PDF]

Discov Oncol
Jeong YJ, Lee NR, Oh HK.
europepmc   +1 more source

Widespread Adaptive Introgression of Major Histocompatibility Complex Genes across Vertebrate Hybrid Zones. [PDF]

Mol Biol Evol
Gaczorek T, Dudek K, Fritz U, Bahri-Sfar L, Baird SJE, Bonhomme F, Dufresnes C, Gvoždík V, Irwin D, Kotlík P, Marková S, McGinnity P, Migalska M, Moravec J, Natola L, Pabijan M, Phillips KP, Schöneberg Y, Souissi A, Radwan J, Babik W.   +20 more
europepmc   +1 more source