Results 171 to 180 of about 133,059 (255)

Using major histocompatibility complex (MHC) II expression to predict antitumor response to CD4 + lymphocyte depletion. [PDF]

Sci Rep
Wang Y, Kim M, Su S, Halwatura L, You S, Kim HL.   +5 more
europepmc   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Correction to: PIPLOM: prediction of exogenous peptide loading on major histocompatibility complex class I molecules. [PDF]

Bioinform Adv
europepmc   +1 more source

The 2024 IPD-MHC database update: a comprehensive resource for major histocompatibility complex studies. [PDF]

Nucleic Acids Res
Maccari G, Robinson J, Barker DJ, Yates AD, Hammond JA, Marsh SGE.   +5 more
europepmc   +1 more source

The lung is more than an organ of gas exchange: immunocompetency, platelets and implications for drug discovery

British Journal of Pharmacology, EarlyView.
Abstract The lungs have for a long time been recognised as having pharmacological significance as a specific organ to modulate the pharmacokinetics of endogenous substances needed to maintain homeostasis. The lungs are therefore the site of action of certain drugs that act on these homeostatic processes, resulting in systemic effects on the ...
Simon C. Pitchford
wiley   +1 more source

A roadmap for T cell receptor-peptide-bound major histocompatibility complex binding prediction by machine learning: glimpse and foresight. [PDF]

Brief Bioinform
Qi F, Huang Q, Xuan Y, Cao Y, Shen Y, Ren Y, Liu Z, Zhang Z.   +7 more
europepmc   +1 more source

Genomic Evolution and Immune Contexture With Therapeutic Relevance in Pancreatic Neuroendocrine Neoplasms

Cancer Science, EarlyView.
Lineage‐dependent immunogenomic landscapes and biologically informed therapy in pancreatic neuroendocrine neoplasms. Pancreatic neuroendocrine neoplasms display lineage‐dependent immunogenomic landscapes, in which genomic alterations, epigenetic states, antigen‐presentation status, immune‐cell infiltration, and suppressive microenvironments co‐evolve ...
Yohei Tabe, Eito Nakagawa, Daisuke Asano, Eriko Katsuta, Daisuke Ban, Shogo Kumagai   +5 more
wiley   +1 more source

Association of Major Histocompatibility Complex Polymorphism With Acute Phase Response in Broiler Chicken. [PDF]

Vet Med Sci
Vatankhah A, Nikbakht Brujeni G, Esmailnejad A.   +2 more
europepmc   +1 more source

Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy

Cancer Science, EarlyView.
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang, Changyi Fan, Shiheng Chen, Tianyue Lu, Yuanyuan Li, Feng Du, Shanshan Wang   +6 more
wiley   +1 more source

Unraveling the architecture of major histocompatibility complex class II haplotypes in rhesus macaques. [PDF]

Genome Res
de Groot N, van der Wiel M, Le NG, de Groot NG, Bruijnesteijn J, Bontrop RE.   +5 more
europepmc   +1 more source