Results 171 to 180 of about 9,502,784 (300)

Clinical, immunological, treatment characteristics, and outcomes in 22 patients with major histocompatibility complex class II deficiency. [PDF]

Front Immunol
Haskologlu S, Aytekin C, Islamoglu C, Kostel Bal S, Baskın K, Erman B, Kendirli T, Ceylaner S, Dogu F, Ikinciogullari A.   +9 more
europepmc   +1 more source

Nail Lichen Planus in Children ‐ Epidemiology, Pathogenesis, Clinical Presentation, and Treatment

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail lichen planus (NLP) is a chronic inflammatory disorder that, while rare in children compared to adults, represents a significant cause of pediatric nail dystrophy that requires early recognition to prevent permanent scarring and nail loss.
Francesca Pampaloni, Matilde Iorizzo
wiley   +1 more source

Identification of new major histocompatibility complex-B haplotypes in chinese broilers. [PDF]

Poult Sci
Chen W, Jia X, Gao Y.
europepmc   +1 more source

Disulfidptosis‐ and Ferroptosis‐Related Gene Signatures in Rheumatoid Arthritis: Association Analysis and Diagnostic Model Construction

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation and progressive joint damage. Although ferroptosis has been implicated in RA progression, the role of disulfidptosis and its interaction with ferroptosis remains unclear.
Ting‐Ting Wang, Dong‐Mei Wang, Xue Li, Yuan‐Li Wei, Ping‐Dan Liu, Shi‐Lin Li, Si‐Ying Xiong, Cai‐Zhen Liu, Fan‐Xin Zeng, Jian‐Hong Wu, Lin Tang   +10 more
wiley   +1 more source

The primate Major Histocompatibility Complex as a case study of gene family evolution. [PDF]

Elife
Fortier AL, Pritchard JK.
europepmc   +1 more source

Major histocompatibility complex class I chain-related A and B molecules and their potential role in virus-associated cancers. [PDF]

World J Virol
Bouayad A.
europepmc   +1 more source

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

Med Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang, Yingying Sun, Yan Zhang, Yifen Shi, Zhiwen Shi   +4 more
wiley   +1 more source

A major histocompatibility complex (MHC) class II molecule that binds the same viral pathogen peptide with both nonamer and decamer core sequences for presentation to T cells. [PDF]

J Virol
Goryanin A, Cook AG, Behboudi S, Kaufman J, Halabi S.   +4 more
europepmc   +2 more sources

Inbreeding does not reduce major histocompatibility complex diversity in the banded mongoose. [PDF]

BMC Ecol Evol
Schubert N, Nichols HJ, Mwanguhya F, Businge R, Kyambulima S, Mwesige K, Cant MA, Winternitz JC.   +7 more
europepmc   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source