Results 1 to 10 of about 97,657 (267)

The Marine Mammal Class II Major Histocompatibility Complex Organization

Frontiers in Immunology, 2019
Sirenians share with cetaceans and pinnipeds several convergent traits selected for the aquatic lifestyle. Living in water poses new challenges not only for locomotion and feeding but also for combating new pathogens, which may render the immune system ...
André Luiz Alves de Sá, André Luiz Alves de Sá, Breanna Breaux, Tibério Cesar Tortola Burlamaqui, Thaddeus Charles Deiss, Leonardo Sena, Michael Frederick Criscitiello, Maria Paula Cruz Schneider   +7 more
doaj   +1 more source

Immunogenetic variation and differential pathogen exposure in free-ranging cheetahs across Namibian farmlands. [PDF]

PLoS ONE, 2012
Genes under selection provide ecologically important information useful for conservation issues. Major histocompatibility complex (MHC) class I and II genes are essential for the immune defence against pathogens from intracellular (e.g.
Aines Castro-Prieto, Bettina Wachter, Joerg Melzheimer, Susanne Thalwitzer, Heribert Hofer, Simone Sommer   +5 more
doaj   +1 more source

Major histocompatibility complex (MHC) fragment numbers alone – in Atlantic cod and in general - do not represent functional variability [version 2; referees: 2 approved, 1 approved with reservations]

F1000Research, 2018
This correspondence concerns a publication by Malmstrøm et al. in Nature Genetics in October 2016. Malmstrøm et al. made an important contribution to fish phylogeny research by using low-coverage genome sequencing for comparison of 66 teleost (modern ...
Johannes M. Dijkstra, Unni Grimholt
doaj   +1 more source

Structure and polymorphism of the major histocompatibility complex class II region in the Japanese Crested Ibis, Nipponia nippon. [PDF]

PLoS ONE, 2014
The major histocompatibility complex (MHC) is a highly polymorphic genomic region that plays a central role in the immune system. Despite its functional consistency, the genomic structure of the MHC differs substantially among organisms.
Yukio Taniguchi, Keisuke Matsumoto, Hirokazu Matsuda, Takahisa Yamada, Toshie Sugiyama, Kosuke Homma, Yoshinori Kaneko, Satoshi Yamagishi, Hiroaki Iwaisaki   +8 more
doaj   +1 more source

MHC Class II Deficiency

Medicine, 2001
IntroductionPrimary human immunodeficiencies constitute a heterogenous group of inborn errors of the immune system due to a variety of genetic abnormalities. The study of patients with primary immunodeficiency diseases has expanded our understanding of immunity.
Villard J, Masternak K, Lisowska-Grospierre B, Fischer A, Reith W   +4 more
openaire   +3 more sources

Major histocompatibility complex (MHC) fragment numbers alone – in Atlantic cod and in general - do not represent functional variability [version 1; referees: 2 approved, 1 approved with reservations]

F1000Research, 2018
This correspondence concerns a publication by Malmstrøm et al. in Nature Genetics in October 2016. Malmstrøm et al. made an important contribution to fish phylogeny research by using low-coverage genome sequencing for comparison of 66 teleost (modern ...
Johannes M. Dijkstra, Unni Grimholt
doaj   +1 more source

The tammar wallaby major histocompatibility complex shows evidence of past genomic instability

BMC Genomics, 2011
Background The major histocompatibility complex (MHC) is a group of genes with a variety of roles in the innate and adaptive immune responses. MHC genes form a genetically linked cluster in eutherian mammals, an organization that is thought to confer ...
Harrow Jennifer, Whilming Laurens, Coggill Penny, Deakin Janine E, Siddle Hannah V, Kaufman Jim, Beck Stephan, Belov Katherine   +7 more
doaj   +1 more source

Chromosome-level genome assembly of Patagonian moray cod (Muraenolepis orangiensis) and immune deficiency of major histocompatibility complex (MHC) class II

Frontiers in Marine Science, 2023
The Patagonian moray cod, Muraenolepis orangiensis, belongs to the family Muraenolepididae and is the sole order of Gadiformes that inhabits the temperate and cold waters of the southern hemisphere.
Jinmu Kim, Seung Jae Lee, Euna Jo, Euna Jo, Eunkyung Choi, Minjoo Cho, Soyun Choi, Jeong-Hoon Kim, Hyun Park   +8 more
doaj   +1 more source

Comparative Genomics of the Major Histocompatibility Complex (MHC) of Felids

Frontiers in Genetics, 2022
This review summarizes the current knowledge on the major histocompatibility complex (MHC) of the family Felidae. This family comprises an important domestic species, the cat, as well as a variety of free-living felids, including several endangered ...
Martin Plasil, Martin Plasil, Jan Futas, Jan Futas, April Jelinek, Pamela A. Burger, Petr Horin, Petr Horin   +7 more
doaj   +1 more source

Gene duplication and fragmentation in the zebra finch major histocompatibility complex

BMC Biology, 2010
Background Due to its high polymorphism and importance for disease resistance, the major histocompatibility complex (MHC) has been an important focus of many vertebrate genome projects. Avian MHC organization is of particular interest because the chicken
Burt David W, Kotkiewicz Holly, Godinez Ricardo, Westerdahl Helena, Völker Martin, Ekblom Robert, Balakrishnan Christopher N, Graves Tina, Griffin Darren K, Warren Wesley C, Edwards Scott V   +10 more
doaj   +1 more source