Results 31 to 40 of about 96,655 (307)

Major histocompatibility complex (MHC) fragment numbers alone – in Atlantic cod and in general - do not represent functional variability [version 2; referees: 2 approved, 1 approved with reservations]

F1000Research, 2018
This correspondence concerns a publication by Malmstrøm et al. in Nature Genetics in October 2016. Malmstrøm et al. made an important contribution to fish phylogeny research by using low-coverage genome sequencing for comparison of 66 teleost (modern ...
Johannes M. Dijkstra, Unni Grimholt
doaj   +1 more source

MHC Class II Deficiency

Medicine, 2001
IntroductionPrimary human immunodeficiencies constitute a heterogenous group of inborn errors of the immune system due to a variety of genetic abnormalities. The study of patients with primary immunodeficiency diseases has expanded our understanding of immunity.
Villard J, Masternak K, Lisowska-Grospierre B, Fischer A, Reith W   +4 more
openaire   +3 more sources

Major histocompatibility complex (MHC) fragment numbers alone – in Atlantic cod and in general - do not represent functional variability [version 1; referees: 2 approved, 1 approved with reservations]

F1000Research, 2018
This correspondence concerns a publication by Malmstrøm et al. in Nature Genetics in October 2016. Malmstrøm et al. made an important contribution to fish phylogeny research by using low-coverage genome sequencing for comparison of 66 teleost (modern ...
Johannes M. Dijkstra, Unni Grimholt
doaj   +1 more source

Structure and polymorphism of the major histocompatibility complex class II region in the Japanese Crested Ibis, Nipponia nippon. [PDF]

PLoS ONE, 2014
The major histocompatibility complex (MHC) is a highly polymorphic genomic region that plays a central role in the immune system. Despite its functional consistency, the genomic structure of the MHC differs substantially among organisms.
Yukio Taniguchi, Keisuke Matsumoto, Hirokazu Matsuda, Takahisa Yamada, Toshie Sugiyama, Kosuke Homma, Yoshinori Kaneko, Satoshi Yamagishi, Hiroaki Iwaisaki   +8 more
doaj   +1 more source

Chromosome-level genome assembly of Patagonian moray cod (Muraenolepis orangiensis) and immune deficiency of major histocompatibility complex (MHC) class II

Frontiers in Marine Science, 2023
The Patagonian moray cod, Muraenolepis orangiensis, belongs to the family Muraenolepididae and is the sole order of Gadiformes that inhabits the temperate and cold waters of the southern hemisphere.
Jinmu Kim, Seung Jae Lee, Euna Jo, Euna Jo, Eunkyung Choi, Minjoo Cho, Soyun Choi, Jeong-Hoon Kim, Hyun Park   +8 more
doaj   +1 more source

Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins [PDF]

, 2014
Major histocompatibility complex class I molecules (MHC I) present peptides to cytotoxic T-cells at the surface of almost all nucleated cells. The function of MHC I molecules is to select high affinity peptides from a large intracellular pool and they ...
van Hateren, Andy, Elliott, Tim, Tim Elliott (201327), Alistair Bailey, Jörn M Werner, Bailey, Alistair, Werner, Jörn M., Tim Elliott, Jörn M. Werner (524999), Andy van Hateren, Alistair Bailey (524997), Andy van Hateren (524998)   +11 more
core   +1 more source

The tammar wallaby major histocompatibility complex shows evidence of past genomic instability

BMC Genomics, 2011
Background The major histocompatibility complex (MHC) is a group of genes with a variety of roles in the innate and adaptive immune responses. MHC genes form a genetically linked cluster in eutherian mammals, an organization that is thought to confer ...
Harrow Jennifer, Whilming Laurens, Coggill Penny, Deakin Janine E, Siddle Hannah V, Kaufman Jim, Beck Stephan, Belov Katherine   +7 more
doaj   +1 more source

Comparative Genomics of the Major Histocompatibility Complex (MHC) of Felids

Frontiers in Genetics, 2022
This review summarizes the current knowledge on the major histocompatibility complex (MHC) of the family Felidae. This family comprises an important domestic species, the cat, as well as a variety of free-living felids, including several endangered ...
Martin Plasil, Martin Plasil, Jan Futas, Jan Futas, April Jelinek, Pamela A. Burger, Petr Horin, Petr Horin   +7 more
doaj   +1 more source

Direct evidence that the N-terminal extensions of the TAP complex act as autonomous interaction scaffolds for the assembly of the MHC I peptide-loading complex [PDF]

, 2012
The loading of antigenic peptides onto major histocompatibility complex class I (MHC I) molecules is an essential step in the adaptive immune response against virally or malignantly transformed cells.
Abele, Rupert, Sabine Hulpke, Tampé, Robert, Ueda, Kazumitsu, Ueda, K., Kazumitsu Ueda, Tomioka, Maiko, Rupert Abele, Tomioka, M., Robert Tampé, Maiko Tomioka, Kremmer, E., Abele, R., Hulpke, S., Hulpke, Sabine, Kremmer, Elisabeth, Tampé, R., Elisabeth Kremmer   +17 more
core   +1 more source

Association between NDO-LID and PGL-1 for leprosy and class I and II human leukocyte antigen alleles in an indigenous community in Southwest Amazon

Brazilian Journal of Infectious Diseases, 2020
The frequencies of the Human leukocyte antigen (HLA) alleles in the Puyanawa indigenous reserve population and their association with the NDO-LID and ELISA PGL-1 rapid serological test was assessed.
Stéfanie Ferreira Teles, Eliane Aparecida Silva, Rodrigo Medeiros de Souza, Jane Tomimori, Marcos Cesar Florian, Rogério Oliveira Souza, Elaine Valim Camarinha Marcos, Fabiana Covolo de Souza-Santana, Mônica Antar Gamba   +8 more
doaj   +1 more source