Frontiers in Immunology, 2021 Structures of peptide-loaded major histocompatibility complex class I (pMHC-I) and class II (pMHC-II) complexes are similar. However, whereas pMHC-II complexes include similar-sized IIα and IIβ chains, pMHC-I complexes include a heavy chain (HC) and a ...
Yanan Wu +4 more
doaj +1 more source
Female rose bitterling prefer MHC-dissimilar males : experimental evidence [PDF]
, 2012 The role of genetic benefits in female mate choice remains a controversial aspect of sexual selection theory. In contrast to “good allele” models of sexual selection, “compatible allele” models of mate choice predict that females prefer mates with ...
Bryja, Pepa +15 more
core +1 more source
Selection and trans-species polymorphism of major histocompatibility complex class II genes in the order Crocodylia. [PDF]
PLoS ONE, 2014 Major Histocompatibility Complex (MHC) class II genes encode for molecules that aid in the presentation of antigens to helper T cells. MHC characterisation within and between major vertebrate taxa has shed light on the evolutionary mechanisms shaping the
Weerachai Jaratlerdsiri +4 more
doaj +1 more source
MHC class I and II genes in Serpentes [PDF]
, 2020 Abstract Genes of the major class I and II histocompatibility complex have been extensively studied in mammals. Studies of these antigens in reptiles are very scarce. Here we describe the characteristics of these genes in the suborder Serpentes.
D.N. Olivieri +2 more
openaire +1 more source
The peptide motif of the single dominantly expressed class I molecule of the chicken MHC can explain the response to a molecular defined vaccine of infectious bursal disease virus (IBDV) [PDF]
, 2013 In contrast to typical mammals, the chicken MHC (the BF-BL region of the B locus) has strong genetic associations with resistance and susceptibility to infectious pathogens as well as responses to vaccines.
Kaufman, Jim +9 more
core +1 more source
Giant panda genomic data provide insight into the birth-and-death process of mammalian major histocompatibility complex class II genes. [PDF]
PLoS ONE, 2009 To gain an understanding of the genomic structure and evolutionary history of the giant panda major histocompatibility complex (MHC) genes, we determined a 636,503-bp nucleotide sequence spanning the MHC class II region.
Qiu-Hong Wan +4 more
doaj +1 more source
Biology, 2016 Major histocompatibility complex (MHC) molecules are key players in initiating immune responses towards invading pathogens. Both MHC class I and class II genes are present in teleosts, and, using phylogenetic clustering, sequences from both classes have ...
Unni Grimholt
doaj +1 more source
Comparative genome analyses reveal distinct structure in the saltwater crocodile MHC.
PLoS ONE, 2014 The major histocompatibility complex (MHC) is a dynamic genome region with an essential role in the adaptive immunity of vertebrates, especially antigen presentation.
Weerachai Jaratlerdsiri +14 more
doaj +1 more source
The Marine Mammal Class II Major Histocompatibility Complex Organization
Frontiers in Immunology, 2019 Sirenians share with cetaceans and pinnipeds several convergent traits selected for the aquatic lifestyle. Living in water poses new challenges not only for locomotion and feeding but also for combating new pathogens, which may render the immune system ...
André Luiz Alves de Sá +7 more
doaj +1 more source
Immunogenetic variation and differential pathogen exposure in free-ranging cheetahs across Namibian farmlands. [PDF]
PLoS ONE, 2012 Genes under selection provide ecologically important information useful for conservation issues. Major histocompatibility complex (MHC) class I and II genes are essential for the immune defence against pathogens from intracellular (e.g.
Aines Castro-Prieto +5 more
doaj +1 more source