Results 181 to 190 of about 242,210 (352)

Evaluation of Endosomal Protonation on Peptide Binding to Class II Major Histocompatibility Complex Molecules [PDF]

, 2013
Crane, Kyle L.
core  

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Twenty years of tuberculosis-driven selection shaped the evolution of the meerkat major histocompatibility complex. [PDF]

Nat Ecol Evol
Müller-Klein N, Risely A, Wilhelm K, Riegel V, Manser M, Clutton-Brock T, Silver L, Santos PSC, Melville DW, Sommer S.   +9 more
europepmc   +1 more source

Joint Public Review: The primate Major Histocompatibility Complex as a case study of gene family evolution

openalex   +1 more source

Genetic Variability of the Major Histocompatibility Complex Class I Homologue Encoded by Human Cytomegalovirus Leads to Differential Binding to the Inhibitory Receptor ILT2

, 2005
Mar Valés‐Gómez, Mitsunori Shiroishi, Katsumi Maenaka, Hugh T. Reyburn   +3 more
openalex   +1 more source

Transcriptomic and proteomic profiling shows dysregulated immune and metabolic pathways in arrhythmogenic cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Aims Arrhythmogenic cardiomyopathy (ACM) is a hereditary heart disease characterized by fibrofatty myocardial replacement and a predisposition to malignant ventricular arrhythmias. The underlying pathomechanisms remain incompletely understood, and specific disease markers are sparse.
Deniz Akdis, Lukas Weidmann, Paolo Nanni, Anna Gaertner, Hendrik Milting, Peter Bode, Corinna Brunckhorst, Liang Chen, Felix C. Tanner, Frank Ruschitzka, Ardan M. Saguner, Firat Duru   +11 more
wiley   +1 more source

Molecular Mechanism for the Selective Presentation of Antigenic Peptides by Major Histocompatibility Complex Class I and Class II Molecules: A Hypothesis. [PDF]

Curr Issues Mol Biol
Zhu BT.
europepmc   +1 more source

Testing for post‐copulatory selection for major histocompatibility complex genotype in a semi‐free‐ranging primate population

, 2013
Joanna M. Setchell, Kristin M. Abbott, Jean‐Paul Gonzalez, Leslie A. Knapp   +3 more
openalex   +2 more sources

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

Exploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li, Haonan Xing, Abid Naeem, Kaiyue Zhang, Aiping Zheng, Yuanyu Huang, Mei Lu   +6 more
wiley   +1 more source

Major Histocompatibility Complex Class I–restricted Cross-presentation Is Biased towards High Dose Antigens and Those Released during Cellular Destruction [PDF]

, 1998
Christian Kurts, Jacques F.A.P. Miller, Rathan M. Subramaniam, Federico Carbone, William R. Heath   +4 more
openalex   +1 more source