Results 11 to 20 of about 50,084 (222)
Successful management of cerebral malaria requires rapid diagnosis, initiation of appropriate antimalarial agents, and aggressive supportive care. The antimalarial used will depend on drug availability, with many of the most effective agents not routinely available in the US.
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La malaria cerebral (MC) es la complicación más frecuente de la malaria por P. falciparum; aproximadamente el 90% de las personas que la han padecido se recuperan completamente sin secuelas neurológicas. Aún no se conoce con claridad su patogénesis pero se han postulado cuatro hipótesis o mecanismos posibles: 1) citoadherencia y secuestro de glóbulos ...
Zapata Zapata, Carlos Hugo+1 more
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This Commentary highlights recent advances in research on cerebral malaria.
Linnie M. Golightly+4 more
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Host Blood Gene Signatures Can Detect the Progression to Severe and Cerebral Malaria
Malaria is a major international public health problem that affects millions of patients worldwide especially in sub-Saharan Africa. Although many tests have been developed to diagnose malaria infections, we still lack reliable diagnostic biomarkers for ...
Mohamed Omar+5 more
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Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions--a prospective multicenter cohort study. [PDF]
BACKGROUND: Severe malaria may influence inner ear function, although this possibility has not been examined prospectively. In a retrospective analysis, hearing impairment was found in 9 of 23 patients with cerebral malaria.
A Freeland+53 more
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Cytokine response during non-cerebral and cerebral malaria: evidence of a failure to control inflammation as a cause of death in African adults [PDF]
Background. With 214 million cases and 438,000 deaths in 2015, malaria remains one of the deadliest infectious diseases in tropical countries. Several species of the protozoan Plasmodium cause malaria.
Yakhya Dieye+8 more
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IFNGR1 polymorphisms in Thai malaria patients [PDF]
Interferon-γ (IFN-γ) has been suggested to play an important role in the pathogenesis of malaria. To examine possible association of the IFN-γ receptor 1 (IFNGR1) polymorphisms with cerebral malaria, 312 adult patients with Plasmodium falciparum malaria (
Hananantachai Hathairad+7 more
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Association of ADAMTS13 polymorphism with cerebral malaria
Background Cerebral malaria is one of the most severe manifestations of Plasmodium falciparum malaria. The sequestration of parasitized red blood cells (PRBCs) to brain microvascular endothelium has been shown to contribute to the pathophysiology of ...
Kraisin Sirima+7 more
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Severe malaria: what's new on the pathogenesis front? [PDF]
Plasmodium falciparum causes the most severe and fatal form of malaria in humans with over half a million deaths each year. Cerebral malaria, a complex neurological syndrome of severe falciparum malaria, is often fatal and represents a major public ...
Grau, Georges Emile Raymond+1 more
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Background Macrophage migration inhibitory factor (MIF) is a multifunctional cytokine implicated in the pathogenesis of a number of human diseases including inflammatory neurological diseases.
Udhayakumar Venkatachalam+7 more
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