Results 11 to 20 of about 966,112 (203)
Advanced Science, 2022 Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum enables their sequestration via attachment to the microvasculature.
Oscar Bate Akide Ndunge +2 more
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Cytokines and Chemokines in Cerebral Malaria Pathogenesis
Frontiers in Cellular and Infection Microbiology, 2017 Cerebral malaria is among the major causes of malaria-associated mortality and effective adjunctive therapeutic strategies are currently lacking. Central pathophysiological processes involved in the development of cerebral malaria include an imbalance of
Josefine Dunst +7 more
doaj +2 more sources
Jurnal Biologi Tropis, 2023 Cerebral malaria is the worst complication of malaria caused by Plasmodium spp. This disease is spread in tropical and subtropical countries and can attack all age groups and genders. The peak incidence occurs in preschool children and very often causes death in children.
Dinda Salsabila +6 more
openaire +2 more sources
Brain Research Bulletin, 2019 Malaria remains of significant public health concern under the tropics, causing millions of deaths annually. The disease is caused by protozoans of the Plasmodium genus, of which harbors several distinct species. Human infection occurs during the blood meal of an infected female mosquito belonging to the Anopheles genus.
Ange Landela Luzolo +1 more
openaire +3 more sources
EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria.
PLoS Pathogens, 2020 Disruption of blood-brain barrier (BBB) function is a key feature of cerebral malaria. Increased barrier permeability occurs due to disassembly of tight and adherens junctions between endothelial cells, yet the mechanisms governing junction disassembly ...
Thayer K Darling +9 more
doaj +2 more sources
CXCL10<sup>high</sup> Microglia in Cerebral Malaria: Toward Translational Validation. [PDF]
CNS Neurosci TherABSTRACT Wang et al. identify CXCL10high TNFαhigh Ki67+ microglia as drivers of CD8+ T cell recruitment during experimental cerebral malaria (ECM). We propose a conservative reframing: rather than asserting a fully validated new taxonomy, CXCL10high microglia should be considered a candidate “neuroimmune endotype” whose translational relevance requires
Rattanapitoon NK +3 more
europepmc +2 more sources
Diagnostic Accuracy of the National Library of Medicine (NLM) Screener Application in Screening for Malaria Parasites Among Blood Donors at the Korle-Bu Blood Bank, Ghana: A Cross-Sectional Study. [PDF]
J Trop MedBackground and Aims Malaria is a deadly disease spread through the bite of an infected female Anopheles mosquito and remains the leading cause of mortality globally. Screening donated blood for malaria parasites is essential to prevent its transmission; however, conventional methods have limitations in accuracy and sensitivity.
Appiah SB +4 more
europepmc +2 more sources
Revista de la Federación Centroamericana de Obstetricia y Ginecología, 2022 Paciente de 35 años, G3P3, indígena, que presenta un parto en casa. Al momento de su admisión con fiebre de 39°C y deterioro neurológico. Se sospechó un shock mix-to, el cual no respondió al manejo en la unidad de cuida-dos intensivos.
O. Reyes
semanticscholar +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 Cerebral malaria (CM) caused by Plasmodium falciparum is a fatal neurological complication of malaria, resulting in coma and death, and even survivors may suffer long-term neurological sequelae.
Xiaonan Song +6 more
semanticscholar +1 more source
Cerebral Malaria: Current Clinical and Immunological Aspects
Frontiers in Immunology, 2022 This review focuses on current clinical and immunological aspects of cerebral malaria induced by Plasmodium falciparum infection. Albeit many issues concerning the inflammatory responses remain unresolved and need further investigations, current ...
K. Albrecht‐Schgoer +3 more
semanticscholar +1 more source