Cerebral malaria caused by Plasmodium falciparum is the severest form of the disease resulting in the morbidity of a huge number of people worldwide. Development of effective curatives is essential in order to overcome the fatality of cerebral malaria ...
Malabika Chakrabarti+5 more
doaj +1 more source
Neuregulin-1 attenuates mortality associated with experimental cerebral malaria. [PDF]
BackgroundCerebral Malaria (CM) is a diffuse encephalopathy caused by Plasmodium falciparum infection. Despite availability of antimalarial drugs, CM-associated mortality remains high at approximately 30% and a subset of survivors develop neurological ...
Anderson, Leonard+7 more
core +2 more sources
BIOMOLECULAR ASPECTS AND UPDATE ON TREATMENT OF CEREBRAL MALARIA
Malaria is still becoming a health problem in the world and in Indonesia. Cerebral malaria is one of many features of severe and life threatening malaria. Many hypotheses underlying the pathophysiology of cerebral malaria have been disclosed, but the one
Machlusil Husna, Bowo Hery Prasetyo
doaj +1 more source
The systemic pathology of cerebral malaria in African children [PDF]
Pediatric cerebral malaria carries a high mortality rate in sub-Saharan Africa. We present our systematic analysis of the descriptive and quantitative histopathology of all organs sampled from a series of 103 autopsies performed between 1996 and 2010 in ...
Carr, Richard+8 more
core +2 more sources
Background Human immunodeficiency virus (HIV)-1 infection increases the burden of malaria by increasing susceptibility to infection and decreasing the response to malarial treatment.
Byarugaba Justus+3 more
doaj +1 more source
Rocaglates as dual-targeting agents for experimental cerebral malaria [PDF]
Cerebral malaria (CM) is a severe and rapidly progressing complication of infection by Plasmodium parasites that is associated with high rates of mortality and morbidity.
Ayi, Kodjo+12 more
core +1 more source
A rare case of young stroke in 16 years old female with Plasmodium vivax malaria infection
Malaria is the most important parasitic disease in the world, in terms of both prevalence and mortality. Infection rate is high due to raise of strains resistant to the antimalarial medicines & social factors.
N U Gediya+3 more
doaj +1 more source
A case report of pitfall of fever and altered mental status: cerebral malaria due to in an adult traveler returning from Congo [PDF]
Background Cerebral malaria, caused by Plasmodium falciparum, can lead to severe neurological complications. It is more frequently observed in children than in adults.
Soo-Hyun Park+4 more
doaj +1 more source
The Economic Costs of Malaria in Children in three Sub-Saharan Countries: Ghana, Tanzania and Kenya. [PDF]
Malaria causes significant mortality and morbidity in sub-Saharan Africa (SSA), especially among children less than five years of age (U5 children).
Constenla, Dagna+4 more
core +2 more sources
Children with cerebral malaria or severe malarial anaemia lack immunity to distinct variant surface antigen subsets [PDF]
Variant surface antigens (VSAs) play a critical role in severe malaria pathogenesis. Defining gaps, or “lacunae”, in immunity to these Plasmodium falciparum antigens in children with severe malaria would improve our understanding of vulnerability to ...
A Bengtsson+42 more
core +2 more sources