Results 101 to 110 of about 249,029 (275)
Changing profile of Plasmodium vivax malaria [PDF]
Background: Malaria, endemic in India, tends to be a major contributor to morbidity and mortality globally. Of the various species, Plasmodium Falciparum is associated with serious prognosis,(morbidity and mortality) in a sizeable number of patients.
M.E. Yeolekar+3 more
openaire +3 more sources
Chloroquine or dihydroartemisinin-piperaquine with either 7- or 14-day primaquine regimens provided highly effective radical cure of vivax malaria on the Thailand-Myanmar border. Short course higher dose primaquine regimens for vivax malaria radical cure
C. Chu+21 more
semanticscholar +1 more source
Malaria "diagnosis" and diagnostics in Afghanistan. [PDF]
In many malaria-endemic areas, including Afghanistan, overdiagnosis of malaria is common. Even when using parasite-based diagnostic tests prior to treatment, clinicians commonly prescribe antimalarial treatment following negative test results.
Ahmad, Tamanna+13 more
core +1 more source
A Novel Inhibitor against the Bromodomain Protein 1 of the Malaria Pathogen Plasmodium Falciparum
This article presents the development of a first‐in‐class inhibitor targeting the bromodomain protein PfBDP1 in Plasmodium falciparum, the deadliest variant of the malaria‐causing Plasmodium parasites. Through structure‐based drug design, the inhibitor interactions were characterized via X‐ray crystallography and isothermal titration calorimetry ...
Marius Amann+10 more
wiley +1 more source
Artemisinin combination therapy for vivax malaria [PDF]
Early parasitological diagnosis and treatment with artemisinin-based combination therapies (ACTs) are key components of worldwide malaria elimination programmes. In general, use of ACTs has been limited to patients with falciparum malaria whereas blood-stage infections with Plasmodium vivax are mostly still treated with chloroquine.
Nicholas M. Anstey+5 more
openaire +4 more sources
Malaria is a vector-borne infectious disease, caused by five different species of the genus Plasmodium, and is endemic to many tropical and sub-tropical countries of the globe.
Nisha Siwal+9 more
semanticscholar +1 more source
AbstrakMalaria merupakan masalah kesehatan yang besar di daerah tropis dan subtropis termasuk di Indonesia. Jenis malaria yang sering terjadi di daerah Sumatera adalah malaria falciparum dan vivax.
Miftahul Jannah Afdhal+2 more
doaj
An ultrasensitive reverse transcription polymerase chain reaction assay to detect asymptomatic low-density Plasmodium falciparum and Plasmodium vivax infections in small volume blood samples. [PDF]
BackgroundHighly sensitive, scalable diagnostic methods are needed to guide malaria elimination interventions. While traditional microscopy and rapid diagnostic tests (RDTs) are suitable for the diagnosis of symptomatic malaria infection, more sensitive ...
Adams, Matthew+16 more
core +2 more sources
Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert+6 more
wiley +1 more source
Predicting malaria dynamics in Burundi using deep Learning Models [PDF]
Malaria continues to be a major public health problem on the African continent, particularly in Sub-Saharan Africa. Nonetheless, efforts are ongoing, and significant progress has been made. In Burundi, malaria is among the main public health concerns. In the literature, there are limited prediction models for Burundi.
arxiv