Village malaria workers for the community-based management of vivax malaria
The Lancet Regional Health - Southeast Asia, 2023 Summary: In Cambodia, malaria cases are on a trajectory towards the goal of malaria elimination by 2025. Vivax malaria is difficult to eliminate because of hypnozoites that can cause relapse.
Bipin Adhikari +6 more
doaj
Plasmodium vivax resistance to chloroquine in Dawei, southern Myanmar. [PDF]
, 2008 OBJECTIVE: To assess the efficacy of chloroquine in the treatment of Plasmodium vivax malaria in in Dawei District, southern Myanmar. METHODS: Enrolled patients at Sonsinphya clinic >6 months of age were assessed clinically and parasitologically every ...
Annerberg, A +9 more
core +2 more sources
Prevention and treatment of vivax malaria
Current Infectious Disease Reports, 2007 Plasmodium vivax is a significant public health threat throughout most of the tropics and to travelers to these regions. The infection causes a debilitating febrile syndrome that often recurs and in rare cases ends in death. The complex life cycle of the parasite compounds the difficulty of prevention and treatment, principally due to the phenomenon of
Baird, J, Schwartz, E, Hoffman, S
openaire +3 more sources
Journal of Vector Borne Diseases, 2023 Background & objectives: Malaria is the most common parasitic infection in children and the most common cause of mortality by vector-borne disease in tropical countries.
Venkatesh Badugu +2 more
doaj +1 more source
Hypnozoite dynamics for Plasmodium vivax malaria: the epidemiological effects of radical cure [PDF]
arXiv, 2021 Malaria is a mosquito-borne disease with a devastating global impact. Plasmodium vivax is a major cause of human malaria beyond sub-Saharan Africa. Relapsing infections, driven by a reservoir of liver-stage parasites known as hypnozoites, present unique challenges for the control of P. vivax malaria.
arxiv
Clinical and Developmental Immunology, 2013 The human malaria is widely distributed in the Middle East, Asia, the western Pacific, and Central and South America. Plasmodium vivax started to have the attention of many researchers since it is causing diseases to millions of people and several ...
Fernanda Versiani +4 more
semanticscholar +1 more source
Strategies for Understanding and Reducing the Plasmodium vivax and Plasmodium ovale Hypnozoite Reservoir in Papua New Guinean Children: A Randomised Placebo-Controlled Trial and Mathematical Model [PDF]
, 2015 The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries.
Bassat, Quique +19 more
core +7 more sources
A spatial multiscale mathematical model of Plasmodium vivax transmission [PDF]
arXiv, 2023 The epidemiological behavior of Plasmodium vivax malaria occurs across spatial scales including within-host, population, and metapopulation levels. On the within-host scale, P. vivax sporozoites inoculated in a host may form latent hypnozoites, the activation of which drives secondary infections and accounts for a large proportion of P.
arxiv
Resolving the cause of recurrent Plasmodium vivax malaria probabilistically
Nature Communications, 2019 Relapses arising from dormant liver-stage Plasmodium vivax parasites (hypnozoites) are a major cause of vivax malaria. However, in endemic areas, a recurrent blood-stage infection following treatment can be hypnozoite-derived (relapse), a blood-stage ...
A. Taylor +10 more
semanticscholar +1 more source
A randomised trial of an eight-week, once weekly primaquine regimen to prevent relapse of plasmodium vivax in Northwest Frontier Province, Pakistan. [PDF]
, 2008 BACKGROUND: Vivax malaria remains a major cause of morbidity in the subtropics. To undermine the stability of the disease, drugs are required that prevent relapse and provide reservoir reduction. A 14-day course of primaquine (PQ) is effective but cannot
Erasmus, Panna +6 more
core +3 more sources