Knowledge and willingness towards malaria vaccines among caregivers in Dar es Salaam, Tanzania [PDF]
Malaria JournalBackground Tanzania is a malaria-endemic country that relies solely on anti-malarial drugs and vector control measures, including insecticide-treated bed nets and indoor residual spraying.
Felista Mwingira +2 more
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Unlocking the potential of novel RTS, S/AS01, and R21/Matrix‐M™ malaria vaccines in African nations [PDF]
Health Science ReportsIntroduction Mass malaria vaccination, rather than vaccinating only children below age 5, has been proven to have the potential to reduce morbidity and mortality among those vaccinated, both young and old. Addressing vaccine scepticism and misinformation
Malik Olatunde Oduoye +11 more
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Physicians’ knowledge of, and willingness to encourage caregivers to partake in the RTS S/AS01 and R21 matrix M malaria vaccines roll out – a national survey in Nigeria [PDF]
BMC Infectious DiseasesBackground The malaria parasite, caused by Plasmodium falciparum, continues to pose serious public health threats in tropical and sub-tropical regions of the world, despite the availability of malaria vaccine.
Mary Aigbiremo Oboh +3 more
doaj +2 more sources
Malaria vaccines and the new malaria agenda [PDF]
Clinical Microbiology and Infection, 2011 The development of an effective malaria vaccine has taken many decades, but there is now a good chance that the first malaria vaccine will be licensed within the next few years. However, this vaccine (RTS,S) will not be fully effective, and more efficacious, second-generation vaccines will be needed.
G A T Targett
exaly +3 more sources
The march toward malaria vaccines [PDF]
Vaccine, 2015 In 2013 there were an estimated 584,000 deaths and 198 million clinical illnesses due to malaria, the majority in sub-Saharan Africa. Vaccines would be the ideal addition to the existing armamentarium of anti-malaria tools. However, malaria is caused by parasites, and parasites are much more complex in terms of their biology than the viruses and ...
Johan Vekemans +2 more
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Correction: A roadmap of priority evidence gaps for the co-implementation of malaria vaccines and perennial malaria chemoprevention [PDF]
Malaria JournalJane Grant +1 more
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Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity [PDF]
Nature, 2021 Sara A Healy +2 more
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Virosome-formulated Plasmodium falciparum AMA-1 & CSP derived peptides as malaria vaccine: randomized phase 1b trial in semi-immune adults & children. [PDF]
, 2011 BACKGROUND\ud \ud This trial was conducted to evaluate the safety and immunogenicity of two virosome formulated malaria peptidomimetics derived from Plasmodium falciparum AMA-1 and CSP in malaria semi-immune adults and children.\ud \ud METHODS\ud \ud The
Abdallah, Mwanajaa Shomari +12 more
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Scientific Reports, 2021 The PfRh5-Basigin ligand–receptor interaction is an essential step in the merozoite invasion process and represents an attractive vaccine target. To reveal genotype–phenotype associations between naturally occurring allelic variants of PfRh5 and invasion
Adam J. Moore +8 more
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Scientific Reports, 2022 The recent stall in the global reduction of malaria deaths has made the development of a highly effective vaccine essential. A major challenge to developing an efficacious vaccine is the extensive diversity of Plasmodium falciparum antigens.
Khadidiatou Mangou +22 more
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