Results 31 to 40 of about 41,093 (223)
Proceedings of the National Academy of Sciences, 1999 Malaria remains one of the most important vector-borne human diseases. Control of malaria caused by Plasmodium falciparum is a major goal, particularly for populations in sub-Saharan Africa. An effective vaccine against malaria that would protect nonimmune individuals from the disease has long been a dream. But will it be a reality?
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Vaccines Against Malaria [PDF]
Clinical Infectious Diseases, 2014 Despite global efforts to control malaria, the illness remains a significant public health threat. Currently, there is no licensed vaccine against malaria, but an efficacious vaccine would represent an important public health tool for successful malaria elimination.
Amed, Ouattara, Matthew B, Laurens
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Modeling the public health impact of malaria vaccines for developers and policymakers [PDF]
, 2013 Efforts to develop malaria vaccines show promise. Mathematical model-based estimates of the potential demand, public health impact, and cost and financing requirements can be used to inform investment and adoption decisions by vaccine developers and ...
Nunes, Julia K. +15 more
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Assessment of parental perception of malaria vaccine in Tanzania [PDF]
, 2015 Clinical trials of the RTS,S malaria vaccine have completed Phase III and the vaccine is on track for registration. Before making decisions about implementation, it is essential to prepare the ground for introducing the vaccine by assessing awareness and
Marcel Tanner +11 more
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Community perceptions of a malaria vaccine in the Kintampo districts of Ghana. [PDF]
, 2013 BACKGROUND: Malaria remains the leading cause of morbidity and mortality in sub-Saharan Africa despite tools currently available for its control. Making malaria vaccine available for routine use will be a major hallmark, but its acceptance by community ...
Timothy S Letsa +11 more
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Simulation of the costs and consequences of potential vaccines for Plasmodium falciparum malaria [PDF]
, 2010 Malaria is one of the major public health problems for low income countries, a major global health priority, and it has also a dramatic economic impact.
Tediosi, Fabrizio
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Biological strategies and political hurdles in developing malaria vaccines
, 2021 Malaria is a devastating parasitic disease for which a vaccine is urgently needed. Seminal studies in the 1940s demonstrated that a whole parasite malaria vaccine could induce protective immunity in ducks and monkeys [1,2].
Good, Michael F, Stanisic, Danielle I
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Malaria vaccine development [PDF]
Clinical Microbiology Reviews, 1994 The malaria parasite life cycle presents several targets for attack, but these different parts of the life cycle are susceptible to different types of host immune response. For example, the sporozoite is most sensitive to immune antibody, while liver stage parasites can be eliminated by cytotoxic T lymphocytes. Attachment of merozoites to erythrocytes,
T R, Jones, S L, Hoffman
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Stakeholders' opinions and questions regarding the anticipated malaria vaccine in Tanzania [PDF]
, 2016 Within the context of combined interventions, malaria vaccine may provide additional value in malaria prevention. Stakeholders' perspectives are thus critical for informed recommendation of the vaccine in Tanzania.
Abdulla, S +29 more
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Future use-cases of vaccines in malaria control and elimination
Parasite Epidemiology and Control, 2020 Malaria burden has significantly changed or decreased over the last 20 years, however, it remains an important health problem requiring the rigorous application of existing tools and approaches, as well as the development and use of new interventions.
Melissa A. Penny +4 more
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