Randomized, Controlled Trial of the Long Term Safety, Immunogenicity and Efficacy of RTS,S/AS02(D) Malaria Vaccine in Infants Living in a Malaria-Endemic Region. [PDF]
, 2013 The RTS,S/AS malaria candidate vaccine is being developed with the intent to be delivered, if approved, through the Expanded Programme on Immunization (EPI) of the World Health Organization.
A Olotu +43 more
core +5 more sources
Experience and Challenges from Clinical Trials with Malaria Vaccines in Africa. [PDF]
, 2013 Malaria vaccines are considered amongst the most important modalities for potential elimination of malaria disease and transmission. Research and development in this field has been an area of intense effort by many groups over the last few decades ...
A Nyika +67 more
core +3 more sources
Uptake of three doses of HPV vaccine by primary school girls in Eldoret, Kenya : a prospective cohort study in a malaria endemic setting [PDF]
, 2018 Background: All women are potentially at risk of developing cervical cancer at some point in their life, yet it is avoidable cause of death among women in Sub- Saharan Africa with a world incidence of 530,000 every year.
Kirop, Elijah +8 more
core +3 more sources
Molecular vaccines for malaria [PDF]
Human Vaccines, 2010 The basic premise of vaccination is the triggering of host immune responses leading to the induction of adaptive immunity having sufficient magnitude and duration to provide long term protection. This has been achieved by many licensed vaccines, the majority based on attenuated or inactivated organisms, although often the protective antigens and ...
Joseph T, Bruder +3 more
openaire +2 more sources
MALVAC 2012 scientific forum: accelerating development of second-generation malaria vaccines
Malaria Journal, 2012 The World Health Organization (WHO) convened a malaria vaccines committee (MALVAC) scientific forum from 20 to 21 February 2012 in Geneva, Switzerland, to review the global malaria vaccine portfolio, to gain consensus on approaches to accelerate second ...
Vannice Kirsten S +3 more
doaj +1 more source
Future use-cases of vaccines in malaria control and elimination
Parasite Epidemiology and Control, 2020 Malaria burden has significantly changed or decreased over the last 20 years, however, it remains an important health problem requiring the rigorous application of existing tools and approaches, as well as the development and use of new interventions.
Melissa A. Penny +4 more
doaj +1 more source
Malaria vaccines 1985-2005: a full circle?
, 2005 Few who were actively engaged in malaria vaccine research 20 years ago (including myself) would have imagined that, in 2005, there would still be a prediction of a 10-20-year horizon before vaccines become part of malaria-control strategies.
Targett, Geoffrey A
core +1 more source
Grid Added Value to Address Malaria [PDF]
, 2006 Through this paper, we call for a distributed, internet-based collaboration to address one of the worst plagues of our present world, malaria. The spirit is a non-proprietary peer-production of information-embedding goods.
Breton, V. +3 more
core +5 more sources
Optimal control analysis of hepatocytic-erythrocytic dynamics of Plasmodium falciparum malaria
Infectious Disease Modelling, 2022 This paper presents an in-host malaria model subject to anti-malarial drug treatment and malaria vaccine antigens combinations. Pontryagin's Maximum Principle is applied to establish optimal control strategies against infected erythrocytes, infected ...
Titus Okello Orwa +2 more
doaj +1 more source
Dendritic cells in plasmodium infection [PDF]
, 2008 Infection with Plasmodium parasites (malaria) contributes greatly to morbidity and mortality in affected areas. Interaction of the protozoan with the immune system has a critical role in the pathogenesis of the disease, but may also hold a key to ...
Alonso +15 more
core +2 more sources