Results 191 to 200 of about 41,093 (223)
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Public Health, 1985
Abstract With the failure of eradication programmes and an exponential rise in the number of persons infected, a malaria vaccine has become a main solution to the control of malaria infection. Early work with birds, rodents and non-human primates gave encouraging results for the development of stage-specific vaccines.
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Abstract With the failure of eradication programmes and an exponential rise in the number of persons infected, a malaria vaccine has become a main solution to the control of malaria infection. Early work with birds, rodents and non-human primates gave encouraging results for the development of stage-specific vaccines.
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Frontiers in Bioscience, 2007
More than 120 years after Alphonse Laveran's discovery of the blood-stage malaria parasite, there is no licensed malaria vaccine and malaria remains the world's most serious parasitic disease. Efforts to develop a vaccine have been thwarted by the complexity of the parasite's life cycle and the ability of the parasite to suppress and evade the immune ...
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More than 120 years after Alphonse Laveran's discovery of the blood-stage malaria parasite, there is no licensed malaria vaccine and malaria remains the world's most serious parasitic disease. Efforts to develop a vaccine have been thwarted by the complexity of the parasite's life cycle and the ability of the parasite to suppress and evade the immune ...
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Acta Tropica, 2003
Besides being a leading cause of morbidity and mortality, malaria is also a cause and consequence of rampant poverty in Africa, where current control efforts are mainly frustrated by antimalaria drug and insecticide resistance. The development of malaria vaccines is therefore a priority for Africa.
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Besides being a leading cause of morbidity and mortality, malaria is also a cause and consequence of rampant poverty in Africa, where current control efforts are mainly frustrated by antimalaria drug and insecticide resistance. The development of malaria vaccines is therefore a priority for Africa.
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Perspectives for malaria vaccination
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1984Abstract The need for vaccines to relieve the current global resurgence of m alaria is apparent. Immunity is specific for each species of hum an m alaria and for each stage in the life cycle. Once protective immunogens have been identified for one species, the homologous molecules in other species may lead to protection.
L H, Miller, P H, David, T J, Hadley
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Adjuvants for malaria vaccines
Parasite Immunology, 2009SummaryThere is a renewed enthusiasm about subunit vaccines for malaria coincident with the formation of new alliances and partnerships raising international public awareness, attracting increased resources and the re‐focusing of research programs on adjuvant development for infectious disease vaccines.
R N, Coler +3 more
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Malaria vaccines for travelers
Travel Medicine and Infectious Disease, 2004Malaria is the most important infectious threat facing travelers to malaria-endemic areas of the tropics, if one considers both risk and potential severity. The problem is illustrated by the many travelers diagnosed with this protozoal infection after returning home from visits to malaria-endemic countries: in the USA, travelers account for 1000–1500 ...
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Malaria vaccines in development
Expert Opinion on Emerging Drugs, 2005The recent infusion of public and private funding for malaria vaccine development has greatly accelerated the pace at which candidate malaria vaccines are entering the clinic. Recent promising results from vaccine trials carried out in malaria-naive and -endemic populations have revealed important insights into what will be required of a successful ...
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New England Journal of Medicine, 2005
Sometime within the next two years, clinical researchers are expected to begin inoculating at least 2000 African infants in the largest trial ever undertaken of an experimental vaccine for malaria....
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Sometime within the next two years, clinical researchers are expected to begin inoculating at least 2000 African infants in the largest trial ever undertaken of an experimental vaccine for malaria....
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New England Journal of Medicine, 1986
The interest in the article1 and letter2 on malaria in this week's Journal stems from developments in research into malarial sporozoites that may lead to an effective vaccine. Anopheline mosquitoes inject sporozoites into humans during a blood meal. Sporozoites rapidly disappear from the blood and enter liver parenchymal cells, where they proliferate ...
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The interest in the article1 and letter2 on malaria in this week's Journal stems from developments in research into malarial sporozoites that may lead to an effective vaccine. Anopheline mosquitoes inject sporozoites into humans during a blood meal. Sporozoites rapidly disappear from the blood and enter liver parenchymal cells, where they proliferate ...
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Trends in Parasitology, 2002
Several books or chapters on vaccines begin with a statement that goes something like this: the virtual elimination of childhood diseases from the face of this earth must surely rank as one of the great accomplishments of medicine. Even a generation ago, children born in many countries of the world were potential victims of devastating diseases such as
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Several books or chapters on vaccines begin with a statement that goes something like this: the virtual elimination of childhood diseases from the face of this earth must surely rank as one of the great accomplishments of medicine. Even a generation ago, children born in many countries of the world were potential victims of devastating diseases such as
openaire +2 more sources