Results 81 to 90 of about 41,093 (223)

Epidemiology of Malaria in an Area Prepared for Clinical Trials in Korogwe, North-eastern Tanzania. [PDF]

, 2009
Site preparation is a pre-requesite in conducting malaria vaccines trials. This study was conducted in 12 villages to determine malariometric indices and associated risk factors, during long and short rainy seasons, in an area with varying malaria ...
Rutta, Acleus S, Martha M Lemnge, Mmbando Bruno P, Lemnge Martha M, Sembuche Samwel H, Kamugisha, Mathias L, Method D Segeja, Deus S Ishengoma, Misago D Seth, Bruno P Mmbando, Francis Filbert, Seth Misago D, Samwel H Sembuche, Kamugisha Mathias L, Acleus S Rutta, Msangeni Hamisi A, Hamisi A Msangeni, Ishengoma Deus S, Ishengoma, Deus S, Mmbando, Bruno P, Msangeni, Hamisi A, Lemnge, Martha M, Segeja Method D, Sembuche, Samwel H, Seth, Misago D, Francis, Filbert, Rutta Acleus S, Segeja, Method D, Mathias L Kamugisha, Filbert Francis   +29 more
core   +1 more source

Assessment of Antibodies Induced by Multivalent Transmission-Blocking Malaria Vaccines

Frontiers in Immunology, 2018
A malaria transmission-blocking vaccine would be a critical tool in achieving malaria elimination and eradication. By using chimpanzee adenovirus serotype 63 and modified vaccinia virus Ankara viral vectored vaccines, we investigated whether ...
Vinay Menon, Melissa C. Kapulu, Iona Taylor, Kerry Jewell, Yuanyuan Li, Fergal Hill, Carole A. Long, Kazutoyo Miura, Sumi Biswas   +8 more
doaj   +1 more source

Life Course Malaria Exposure and SARS‐CoV‐2 Seroepidemiology in Ugandan Adolescents: A Longitudinal Study Nested in a Birth Cohort

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background COVID‐19 has had major global health impacts, yet reported morbidity and mortality have been lower in Africa despite serological evidence of widespread infection. Malaria has been proposed as a potential modifier of susceptibility to and outcomes of SARS‐CoV‐2 infection.
Ludoviko Zirimenya, Doreen Nayebare, Claire Baine, Jacent Nassuuna, Milly Namutebi, Christopher Zziwa, Denis Nsubuga, Fred Kiwudhu, Florence Akello, Josephine Tumusiime, Gloria Oduru, Grace Kabami, Hellen Akurut, Rachel Nakyesige, Agnes Natukunda, Anne Wajja, Lawrence Lubyayi, Simon Kimuda, Gyaviira Nkurunungi, Jennifer Serwanga, Katie J. Doores, Emily L. Webb, Alison M. Elliott   +22 more
wiley   +1 more source

Evidence of blood stage efficacy with a virosomal malaria vaccine in a Phase IIa clinical trial

, 2008
Background Previous research indicates that a combination vaccine targeting different stages of the malaria life cycle is likely to provide the most effective malaria vaccine.
Zurbriggen, R, Gerd Pluschke, Sarah C. Gilbert, Hill, Adrian, Hutchings, Claire, Gilbert Sarah C., Sinden, Robert, Gilbert, Sarah, Pluschke, G, Gilbert, Sarah C., Zurbriggen Rinaldo, Vogel, Denise, Jack L. Williams, Correa, S, Andrews Laura, Okitsu, SL, Westerfeld Nicole, Andrews, Laura, Vogel, D, David W. Porter, Thompson, Fiona, Okitsu, Shinji, Ian Poulton, Todryk, S, Shinji L. Okitsu, Denise Vogel, Dunachie Susanna, Thompson Fiona M., Berthoud, Tamara, Andrews, L, Sinden, R, Porter David W., Pluschke, Gerd, Sarah C Gilbert, Sinden Robert, Poulton Ian, Fiona M Thompson, Berthoud, T, Zurbriggen, Rinaldo, Rinaldo Zurbriggen, Susanna Dunachie, Westerfeld, Nicole, Tamara Berthoud, Todryk, Stephen, Okitsu Shinji L., Hill Adrian V. S., Correa Simon, Berthoud Tamara, Dunachie, S, Westerfeld, N, David W Porter, Nicole Westerfeld, Todryk Stephen, Porter, David, Correa, Simon, Thompson, FM, Pluschke Gerd, Hutchings, C, Poulton, Ian, Hutchings Claire, Williams, JL, Vogel Denise, Shinji L Okitsu, Fiona M. Thompson, Poulton, I, Jack L Williams, Simon Correa, Laura Andrews, Dunachie, Susanna, Adrian V S Hill, Robert Sinden, Porter, DW, Stephen Todryk, Williams, Jack, Claire Hutchings, Williams Jack L.   +75 more
core   +1 more source

Validation of Health Belief Model and Theory of Planned Behaviour Constructs for Predicting Malaria Vaccine Acceptance in Ghana: A Partial Least Squares Structural Equation Modelling Approach

Tropical Medicine &International Health, EarlyView.
ABSTRACT Aim This study examines the predictive power of constructs from the health belief model (HBM) and theory of planned behaviour (TPB) in explaining malaria vaccine acceptance in Ghana in the post‐COVID‐19 era, while also assessing the reliability of these constructs within this context.
Michael Sarfo, Michael Snowden, Jamie P. Halsall   +2 more
wiley   +1 more source

Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malaria. [PDF]

, 2008
Individuals living in areas where malaria is endemic are repeatedly exposed to many different malaria parasite antigens. Studies on naturally acquired antibody-mediated immunity to clinical malaria have largely focused on the presence of responses to ...
Mackinnon, Margaret J, Lowe, B, Cavanagh, DR, Bull, PC, Osier, Faith HA, Jana S. McBride, Tetteh, Kevin KA, Conway, David J., Verra, Federica, Murungi, Linda, Fegan, Gregory, Tetteh, KK, Federica Verra, Spencer D. Polley, Cavanagh, David R, Lowe, Brett, Osier, Faith H. A., Lanar, David E., Conway, DJ, Mwangi, T, Mwangi, Tabitha, Fegan, G, Lanar, David E, Lanar, DE, Thomas, AW, Thornas, Alan W., McBride, Jana S., Gregory Fegan, David J. Conway, Murungi, L, Conway, David J, David R. Cavanagh, McBride, Jana S, Tabitha Mwangi, Kevin Marsh, Bull, Peter, Polley, SD, McBride, JS, Peter C. Bull, Cavanagh, David R., Mackinnon, MJ, Verra, F, Greg Fegan, Faith H. A. Osier, Brett Lowe, Alan W. Thomas, Polley, Spencer D, David E. Lanar, Linda Murungi, Kevin K. A. Tetteh, Osier, FH, Mackinnon, Margaret J., Marsh, K, Tetteh, Kevin K. A., Margaret J. Mackinnon, Mackinnon, Margaret, Bull, Peter C., Thomas, Alan W, Marsh, Kevin, Polley, Spencer D., Bull, Peter C   +60 more
core   +1 more source

An international study on emerging arboviral infections and blood safety

Transfusion, EarlyView.
Abstract Background Emerging and re‐emerging arboviral infections are a risk to blood safety. We conducted an international survey on how blood establishments respond to current and future arbovirus threats. Study Design and Methods A questionnaire on arbovirus donor deferral strategies, pathogen reduction, and donation screening was distributed to ...
Piya Rajendra, Helen M. Faddy, Daniel Candotti, Carolina B. Bub, Jose M. Kutner, Steven J. Drews, Carmen L. Charlton, Sheila F. O'Brien, Wai‐Chiu Tsoi, Michel‐Andres Garcia‐Otalora, Claire Reynolds, Tuulia Palukka, Riikka Lehtisalo, Ruth Offergeld, Axel Seltsam, Marijke Weber‐Schehl, Nahid Chenarsabz, Naoko Goto, Sung‐Chan Park, So‐Yong Kwon, Ryanne Lieshout‐Krikke, Aneta Kopacz, Ewa Sulkowska, Oana‐Alexandra Șerban, Simona Ruta, Eugene Zhiburt, Maha Badawi, Josephine Mitchel, Ute Jentsch, Ángel Luis Pajares Herraiz, Ana Lafuente Guijosa, Gülşen Özkaya Şahin, Christoph Niederhauser, Marion C. Lanteri, Brian Custer, Galen Conti, Anthea Cheng, Shannah Secret, Peter Simmonds, Heli Harvala, on behalf of the Virology subgroup of the ISBT WP‐TTID   +40 more
wiley   +1 more source

Extended follow-up following a phase 2b randomized trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya [PDF]

, 2007
Background. "FFM ME-TRAP'' is sequential immunisation with two attenuated poxvirus vectors (FP9 and modified vaccinia virus Ankara) delivering the pre-erythrocytic malaria antigen ME-TRAP.
Gilbert, SC, Lang, Trudie, Bejon, P, Hill, Adrian, Tabitha Mwangi, Kevin Marsh, Hill, AVS, Gilbert Sarah C., Gilbert, Sarah, Lang Trudie, Lang, T, Peshu, N, Mwangi Tabitha, Edna Ogada, Norbert Peshu, Hill, Adrian VS, Paul Milligan, Greg Fegan, Fegan Greg, Milligan Paul, Gilbert, Sarah C, Peshu, Norbert, Philip Bejon, Bejon, Philip, Milligan, Paul, Marsh Kevin, Marsh, K, Mwangi, T, Hill Adrian V.S., Fegan, G, Mwangi, Tabitha, Peshu Norbert, Trudie Lang, Bejon Philip, Ogada Edna, Fegan, Greg, Milligan, P, Ogada, Edna, Adrian V S Hill, Ogada, E, Marsh, Kevin, Sarah C Gilbert   +41 more
core   +1 more source

Malaria Vaccine Development: The Need for Novel Approaches: A Review Article

Iranian Journal of Parasitology, 2018
Background: Although rigorous efforts have substantially decreased the malaria burden through decades, it still threatens the lives of millions of children. Development of an effective vaccine can provide important approach in malaria control strategies.
Shima MAHMOUDI, Hossein KESHAVARZ
doaj  

Advances in transmission-blocking vaccines against Plasmodium falciparum and Plasmodium vivax

Expert Review of Vaccines
Introduction The World Health Organization has recommended two pre-erythrocytic malaria vaccines targeting Plasmodium falciparum. However, there is currently no vaccine available for Plasmodium vivax, the second leading cause of malaria.
Mayumi Tachibana, Eizo Takashima, Motomi Torii, Yimin Wu, Jetsumon Sattabongkot, Takafumi Tsuboi   +5 more
doaj   +1 more source