Results 91 to 100 of about 41,093 (223)

De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi, Alastair G. McEwan, Ulrike Kappler   +2 more
wiley   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, Volume 150, Issue 7, Page 990-1015, August 2026.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Relationship between the entomologic inoculation rate and the force of infection for Plasmodium falciparum malaria. [PDF]

, 2006
We propose a stochastic model for the relationship between the entomologic inoculation rate (EIR) for Plasmodium falciparum malaria and the force of infection in endemic areas.
Maire, Nicolas, Molineaux, Louis, Killeen, Gerry F, Smith, Thomas, Vounatsou, Penelope, Dietz, Klaus, Tanner, Marcel   +6 more
core  

Spread of anti-malarial drug resistance: mathematical model with implications for ACT drug policies. [PDF]

, 2008
BACKGROUND: Most malaria-endemic countries are implementing a change in anti-malarial drug policy to artemisinin-based combination therapy (ACT). The impact of different drug choices and implementation strategies is uncertain.
Hastings, Ian M, Day, Nicholas PJ, White, Nicholas J., Dondorp, AM, Hastings, Ian M., Dondorp, Arjen M, Dondorp, Adrianus, Hastings, Ian, Day, Nicholas P. J., Pongtavornpinyo, W, Hastings, IM, Pongtavornpinyo, Wirichada, White, Nicholas J, Day, Nicholas, Day, Nicholas P.J., Yeung, Shunmay, Day, NP, White, NJ, White, Nicholas, Dondorp, Arjen M., Yeung, S   +20 more
core   +1 more source

A landscape review of malaria vaccine candidates in the pipeline

Tropical Diseases, Travel Medicine and Vaccines
Background Globally, malaria continues to pose a major health challenge, with approximately 247 million cases of the illness and 627,000 deaths reported in 2021.
Yusuf Amuda Tajudeen, Habeebullah Jayeola Oladipo, Sodiq Inaolaji Yusuff, Samuel O. Abimbola, Muritala Abdulkadir, Iyiola Olatunji Oladunjoye, Abass Olawale Omotosho, Oluwaseyi Muyiwa Egbewande, Hameedat Damilola Shittu, Rashidat Onyinoyi Yusuf, Oluwatosin Ogundipe, Abdulbasit Opeyemi Muili, Abdullateef Opeyemi Afolabi, Salwa M. A. Dahesh, Marwa Ahmed Mahmoud Gameil, Mona Said El-Sherbini   +15 more
doaj   +1 more source

Malaria chemoprophylaxis and the serologic response to measles and diphtheria-tetanus-whole-cell pertussis vaccines

Malaria Journal, 2005
Background Acute malaria has been associated with a decreased antibody response to tetanus and diphtheria toxoids, meningococcal, salmonella, and Hib vaccines.
Saliou Pierre, Lobel Hans O, Collins William E, Meade Bruce D, Manclark Charles R, Breman Joel G, Rosen Jennifer B, Roberts Jacquelin M, Campaoré Pierre, Miller Mark A   +9 more
doaj   +1 more source

Hematology and Serum Biochemistry Reference Intervals for Captive‐Born Owl Monkeys (Aotus nancymae): Effects of Age and Sex

Journal of Medical Primatology, Volume 55, Issue 4, August 2026.
ABSTRACT Background Owl monkeys (Aotus spp.) are a nocturnal nonhuman primate (NHP) native to central and South America that are used as infectious disease research models for human diseases, such as malaria and human immunodeficiency virus. Natural and infectious diseases may cause alterations in the hematology and serum biochemistry values, which ...
Sarah M. Kezar, Sarah J. Neal, Gregory K. Wilkerson   +2 more
wiley   +1 more source

Serological and molecular tools for the evaluation of malaria transmission blocking vaccines [PDF]

Malaria transmission blocking vaccines (TBV) have been prioritized as an intervention to facilitate malaria elimination, but tools are required to support roll-out and evaluation.
Jones, SCP
core   +1 more source

Seasonal vaccination against malaria: a potential use for an imperfect malaria vaccine

Malaria Journal, 2017
In many parts of the African Sahel and sub-Sahel, where malaria remains a major cause of mortality and morbidity, transmission of the infection is highly seasonal.
Brian Greenwood, Alassane Dicko, Issaka Sagara, Issaka Zongo, Halidou Tinto, Matthew Cairns, Irene Kuepfer, Paul Milligan, Jean-Bosco Ouedraogo, Ogobara Doumbo, Daniel Chandramohan   +10 more
doaj   +1 more source

IL‐33/ST2 Signaling Sustains Hepato‐Intestinal Homeostasis by Orchestrating Vascular Surveillance and Immune Regulatory Circuits During Experimental Trypanosoma cruzi Infection

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Impairment of hepato‐intestinal homeostasis triggered by ST2 deficiency during T. cruzi infection. Within the splenic compartment, immune dysregulation is marked by a robust pro‐inflammatory polarization of the T‐cell landscape. In the liver, ST2 deficiency is associated with hepatocellular injury, increased parasite burden, and hyperalbuminemia ...
Marcelo Eduardo Cardozo, Tatyane Martins Cirilo, José Bryan da Rocha Rihs, Jorge Lucas Nascimento Souza, Isabela de Brito Duval, Ana Rafaela Antunes‐Porto, Luisa Vitor Braga do Amaral, Fernando Bento Rodrigues Oliveira, Mayra Fernanda Ricci, Laura Lis de Oliveira Santos, Lívia Fernanda Dias Santana, Luiza Pinheiro Silva, Chiara Cássia Oliveira Amorim, Gabriela Gomes Monteiro Lemos, Getulío Mota e Silva Junior, Izabela da Silva Oliveira, Marina Possa dos Reys, Ana Laura Grossi de Oliveira, Geovanni Dantas Cassali, Luisa Mourão Dias Magalhães, Lilian Lacerda Bueno, Fabiana Simão Machado, Ricardo Toshio Fujiwara   +22 more
wiley   +1 more source