Results 131 to 140 of about 132,821 (306)

Evaluation of FilmArray Multiplex PCR Test Results in Bloodstream Infections in Oncological Patients

Journal of Clinical Laboratory Analysis, EarlyView.
In this study conducted at an oncology hospital, BCID2 panel results for the rapid identification of microorganisms and resistance genes in positive blood culture samples were compared with conventional culture methods. The BCID2 panel provided faster results and showed a high correlation with traditional methods.
İpek Mumcuoğlu, Sevgi Şahin, Esra Tavukcu, Neşe İnan, Ayşe Semra Güreser, Serap Süzük Yıldız, Tuba Dal   +6 more
wiley   +1 more source

The Evaluation of Machine Learning Models Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF-MS) Spectra for the Prediction of Antibiotic Resistance in Klebsiella pneumoniae. [PDF]

Microbiologyopen
Machine learning models developed from matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry spectra can rapidly predict antimicrobial resistance in Klebsiella pneumoniae. By transforming routine spectral data into accurate resistance profiles within minutes, this approach could reduce diagnostic delays and support earlier ...
Fordham SME.
europepmc   +2 more sources

MALDI-TOF mass spectrometry of Cyanobacteria: a global approach to the discovery of novel secondary metabolites [PDF]

, 2008
Cyanobacteria (blue-green algae) are a group of ancient prokaryotic organisms dating back between three and four billion years.¹ They have been attributed with oxygenating the earth’s atmosphere² but, since the anthropogenic euthrophication of lakes ...
Prinsep, Michèle R., Puddick, Jonathan
core  

Synthesis of Telechelic‐Type Polypeptides Functionalized with Aromatic Units and the Characterization of Their Structures and Thermal Properties

Macromolecular Rapid Communications, EarlyView.
Polypeptide chains were extended from both ends of aromatic diamines by chemoenzymatic polymerization, resulting in the synthesis of telechelic polyglycines (TPG) and polyalanines (TPA). These telechelic polymers assembled into branched nanofibrils through π‐π stacking of aromatic rings, with the polymer backbones bent at the aromatic unit.
Yusuke Ueno, Kousuke Tsuchiya, Hiroyasu Masunaga, Keiji Numata   +3 more
wiley   +1 more source

Innovative strategies against superbugs: Developing an AI-CDSS for precise Stenotrophomonas maltophilia treatment

Journal of Global Antimicrobial Resistance
Objectives: The World Health Organization named Stenotrophomonas maltophilia (SM) a critical multi-drug resistant threat, necessitating rapid diagnostic strategies.
Tai-Han Lin, Hsing-Yi Chung, Ming-Jr Jian, Chih-Kai Chang, Hung-Hsin Lin, Ching-Mei Yu, Cherng-Lih Perng, Feng-Yee Chang, Chien-Wen Chen, Hung-Sheng Shang   +9 more
doaj   +1 more source

Diacetylene‐Functionalized Glycan Mimetics for Receptor‐Mediated Cluster Imprinting in Model Membranes

Macromolecular Rapid Communications, EarlyView.
Diacetylene‐containing glycan mimetics cluster upon selective lectin binding in GUVs. Subsequent irradiation leads to the formation of fluorescent polymer clusters, while non‐clustered glycan mimetics remain unaffected in the membrane. ABSTRACT The glycocalyx, a dense layer of glycoproteins and glycolipids on eukaryotic cells, is essential for cellular
Luca‐Cesare Blawitzki, Lina Charlotte Assenmacher, Nicholas Jäck, Stephan Schmidt, Cornelia Monzel, Laura Hartmann   +5 more
wiley   +1 more source

A Non‐Antigenic Randomized Polyethylene Glycol/Poly(2‐Phenyl‐2‐Oxazine)‐Based Drug Delivery Platform

Macromolecular Rapid Communications, EarlyView.
Randomized PEG (rPEG), a conceptually new PEG alternative, is combined with poly(2‐phenyl‐2‐oxazine) (PPheOzi) to establish an rPEG‐b‐PPheOzi‐b‐rPEG micellar drug delivery platform. The PPheOzi block enables high drug loadings, while competitive ELISA reveals a drastic reduction in anti‐PEG antibody affinity of rPEG in comparison to PEG.
Julian Schmidt, Anna‐Lena Ziegler, Florian T. Kaps, Laura J. Rosenberger, Matthias Bros, Holger Frey, Robert Luxenhofer   +6 more
wiley   +1 more source

Candida antarctica lipase-catalyzed synthesis and characterization of novel acrylic teroligomers [PDF]

, 2018
The synthesis of three novel low molecular weight acrylic terpolymers, containing at random sequences of ethyl acrylate, acrylic acid and N-(2-hydroxyethyl)acrylamide, catalyzed by Candida antarctica lipase was successfully conducted in organic media ...
Baldessari, Alicia, Erra Balsells, Rosa, Fatema, M. Kaniz, Nonami, Hiroshi, Rustoy, Eduardo Miguel   +4 more
core  

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

Mass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source