Results 161 to 170 of about 197,934 (334)

Porphyrin‐Geländer–Helical Conjugated Banister Type Porphyrin Dyads

Chemistry – A European Journal, EarlyView.
Porphyrin arrays go chiral–A porphyrin Geländer macrocycle represents the intriguing prototype architecture of helically chiral butadiyne‐linked porphyrin arrays. This study combines synthetic, spectroscopic, and computational methods to shed light on its structure, chiroptical properties, and tunability, highlighting its promise for advancing ...
Joël F. Keller, Adriano D'Addio, Marcel Mayor   +2 more
wiley   +1 more source

Innovative strategies against superbugs: Developing an AI-CDSS for precise Stenotrophomonas maltophilia treatment

Journal of Global Antimicrobial Resistance
Objectives: The World Health Organization named Stenotrophomonas maltophilia (SM) a critical multi-drug resistant threat, necessitating rapid diagnostic strategies.
Tai-Han Lin, Hsing-Yi Chung, Ming-Jr Jian, Chih-Kai Chang, Hung-Hsin Lin, Ching-Mei Yu, Cherng-Lih Perng, Feng-Yee Chang, Chien-Wen Chen, Hung-Sheng Shang   +9 more
doaj   +1 more source

Hydrogels Formed by the Self‐Assembly of Collagen‐Mimetic Peptides With a Constrained Backbone Structure

Chemistry – A European Journal, EarlyView.
Kinked collagen‐mimetic peptides (kinkCMPs), whose backbone is constrained by a disulfide bond, are designed to induce hydrogel formation. The kinked backbone promotes supramolecular assembly into tunable hydrogels with thermal stability depending on length.
Moeka Noto, Kazunori K. Fujii, Yuetsu Shu, Takashi Hiroi, Takaki Koide   +4 more
wiley   +1 more source

Self‐Calibrating Ratiometric DNA Aptamer Probe for Quantitative ATP Imaging in Living Cells

Chemistry – A European Journal, EarlyView.
We developed the RFA–ECHO probe, an internally calibrated ATP sensor that remains responsive across millimolar ATP levels. Its self‐correcting Cy5/ECHO ratio ensures accurate quantification independent of probe uptake. Compared with FRET‐based sensors, it yields a robust ratiometric shift, distinguishing high‐ATP cancer cells from normal ones, enabling
Yunsong Xu, Kunihiko Morihiro, Rui Cong, Samruddhi Maheshwar Patil, Idoia Wille, Akimitsu Okamoto   +5 more
wiley   +1 more source

Metal‐Directed Self‐Assembly in a Beta‐Sheet Miniprotein Scaffold

European Journal of Inorganic Chemistry, EarlyView.
A rationally engineered miniprotein, V14C, which is based on the beta β‐sheet Foldon domain, self‐assembles via a metal‐binding site to form well‐defined oligomers in the presence of Zn2+, Hg2+, and Cd2+. This modular design expands the toolbox for creating custom metalloproteins, enabling studies of metal–protein interactions for biochemical functions
Chandan Muni Reddy, Marcos R. Conde González, Jürgen H. Gross, Franziska Thomas   +3 more
wiley   +1 more source

Nonribosomal peptides, key biocontrol components for Pseudomonas fluorescens In5, isolated from a Greenlandic suppressive soil. [PDF]

, 2015
UnlabelledPotatoes are cultivated in southwest Greenland without the use of pesticides and with limited crop rotation. Despite the fact that plant-pathogenic fungi are present, no severe-disease outbreaks have yet been observed.
Dorrestein, Pieter C, Glaring, Mikkel A, Kersten, Roland, Koyama, Nobuhiro, Michelsen, Charlotte F, Stougaard, Peter, Watrous, Jeramie   +6 more
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Sulfur‐Rich μ‐O Diiron Catalyst for Electrochemical Hydrogen Production

European Journal of Inorganic Chemistry, EarlyView.
A diferric μ‐oxido complex supported by a sulfur‐rich scaffold acts as a proton‐reduction electrocatalyst for H2 production via a μ‐hydroxido species. An aminodithiophenolate scaffold with an NS2 donor set supports diiron complex formation. The diferrous precursor activates O2, giving rise to a diferric μ‐oxido species, which acts as a proton‐reduction
Hugo C. Hernández‐Toledo, Víctor E. López‐Guerrero, Alexander Mondragón‐Díaz, Elvis Robles‐Marín, Marcos Flores‐Alamo, José Manuel Guevara‐Vela, Tomás Rocha‐Rinza, Ivan Castillo   +7 more
wiley   +1 more source

Rapid detection of rifampin resistance in Mycobacterium tuberculosis using nucleotide MALDI-TOF MS: a comparative study with phenotypic drug susceptibility testing and DNA sequencing

Microbiology Spectrum
Rifampin (RIF) resistance in Mycobacterium tuberculosis (M.tb) is primarily caused by mutations in the rpoB gene. Rapid and accurate detection of RIF resistance is critical for effective tuberculosis (TB) control.
Junxian Zhang, Haiyan Zhang, Jie Wang, Wenna Sun, Yan Liang, Yourong Yang, Qingwei Ma, Xueqiong Wu   +7 more
doaj   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

Misidentification of Candida guilliermondii as C. famata among Strains Isolated from Blood Cultures by the VITEK 2 System [PDF]

, 2014
Introduction. The aim of this study was to differentiate between Candida famata and Candida guilliermondii correctly by using matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) and gene sequencing. Methods. Twenty-
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