Results 11 to 20 of about 197,934 (334)

Novel application of automated machine learning with MALDI-TOF-MS for rapid high-throughput screening of COVID-19: a proof of concept

open access: yesScientific Reports, 2021
The 2019 novel coronavirus infectious disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created an unsustainable need for molecular diagnostic testing.
N. Tran   +7 more
semanticscholar   +1 more source

Performance of MALDI–TOF Mass Spectrometry in the Philippines

open access: yesTropical Medicine and Infectious Disease, 2021
Identification of the causative pathogen in infectious diseases is important for surveillance and to guide treatment. In low- and middle-income countries (LMIC), conventional culture and identification methods, including biochemical methods, are ...
Morichika Osa   +16 more
doaj   +1 more source

Matrix-assisted laser desorption ionization-time of flight mass spectrometry for the identification of clinically relevant bacteria. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) allows rapid and reliable identification of microorganisms, particularly clinically important pathogens.
Cinzia Benagli   +4 more
doaj   +1 more source

A high-throughput MALDI-TOF MS biochemical screen for small molecule inhibitors of the antigen aminopeptidase ERAP1

open access: yesSLAS Discovery, 2023
MALDI-TOF MS is a powerful analytical technique that provides a fast and label-free readout for in vitro assays in the high-throughput screening (HTS) environment.
Leonie Müller   +11 more
doaj   +1 more source

How MALDI-TOF Mass Spectrometry Technology Contributes to Microbial Infection Control in Healthcare Settings

open access: yesVaccines, 2022
Healthcare settings have been utilizing matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) since 2010. MALDI-TOF MS has various benefits over the conventional method of biochemical identification, including ease ...
Ayman Elbehiry   +11 more
doaj   +1 more source

Multicentre study on the reproducibility of MALDI-TOF MS for nontuberculous mycobacteria identification

open access: yesScientific Reports, 2022
The ability of MALDI-TOF for the identification of nontuberculous mycobacteria (NTM) has improved recently thanks to updated databases and optimized protein extraction procedures.
D. Rodríguez-Temporal   +25 more
semanticscholar   +1 more source

MALDI-TOF MS in a Medical Mycology Laboratory: On Stage and Backstage

open access: yesMicroorganisms, 2021
The implementation of MALDI-TOF MS in medical microbiology laboratories has revolutionized practices and significantly reduced turnaround times of identification processes.
Marie G Robert   +10 more
semanticscholar   +1 more source

Performance evaluation and clinical validation of optimized nucleotide MALDI-TOF-MS for mycobacterial identification

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
ObjectiveTo evaluate the performance and validate the diagnostic value of a nucleotide matrix-assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF-MS) with the analysis process optimized in identification of mycobacterium species ...
Baiying Li   +13 more
doaj   +1 more source

MALDI-TOF MS in Prenatal Genomics [PDF]

open access: yesTransfusion Medicine and Hemotherapy, 2009
Prenatal diagnosis aims either to provide the reassurance to the couples at risk of having an affected child by timely appropriate therapy or to give the parents a chance to decide the fate of the unborn babies with health problems. Invasive prenatal diagnosis (IPD) is accurate, however, carrying a risk of miscarriage.
Zhong, Xiao Yan, Holzgreve, Wolfgang
openaire   +4 more sources

Integrative Description of Cryptic Tigriopus Species From Korea Using MALDI-TOF MS and DNA Barcoding

open access: yesFrontiers in Marine Science, 2021
MALDI Time-of-Flight Mass Spectrometry (MALDI-TOF MS) provides a fast and reliable alternative method for species-level identification of pathogens and various metazoans.
Jisu Yeom   +3 more
doaj   +1 more source

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