Results 31 to 40 of about 1,973,836 (223)

Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity

Nature Communications, 2023
Male meiosis relies on canonical centrosomes for spindle formation, but how this differs from acentrosomal oocyte meiosis is unclear. Here they show that spindle formation in sperm relies on DYNLRB2, similar to the activity of DYNLRB1 in mitotic cells.
Shuwen He, John P. Gillies, Juliana L. Zang, Carmen M. Córdoba-Beldad, Io Yamamoto, Yasuhiro Fujiwara, Julie Grantham, Morgan E. DeSantis, Hiroki Shibuya   +8 more
doaj   +1 more source

The multicopy gene Sly represses the sex chromosomes in the male mouse germline after meiosis. [PDF]

, 2009
Studies of mice with Y chromosome long arm deficiencies suggest that the male-specific region (MSYq) encodes information required for sperm differentiation and postmeiotic sex chromatin repression (PSCR).
Yamauchi, Yasuhiro, Julie Cocquet, Nabeel A Affara, Burgoyne, Paul S., Yasuhiro Yamauchi, Cocquet, Julie, Affara, Nabeel A., Mahadevaiah, Shantha K., Ellis, Peter J.I., Peter J I Ellis, Monika A Ward, Shantha K Mahadevaiah, Ward, Monika A., Paul S Burgoyne   +13 more
core   +1 more source

The cell cycle timing of centromeric chromatin assembly in Drosophila meiosis is distinct from mitosis yet requires CAL1 and CENP-C.

PLoS Biology, 2012
CENP-A (CID in flies) is the histone H3 variant essential for centromere specification, kinetochore formation, and chromosome segregation during cell division.
Elaine M Dunleavy, Nicole L Beier, Walter Gorgescu, Jonathan Tang, Sylvain V Costes, Gary H Karpen   +5 more
doaj   +1 more source

DNA replication licensing in somatic and germ cells [PDF]

, 2004
The DNA replication (or origin) licensing system ensures precise duplication of the genome in each cell cycle and is a powerful regulator of cell proliferation in metazoa.
Williams, C, Jung, Hyo-Il, Obermann, EC, Ellen C. Obermann, Kai Stoeber, Loddo, Marco, Kathryn Leigh Eward, Marco Loddo, Shreeram, S, Williams, GH, Obermann, Ellen C, Hyo-Il Jung, Williams, Craig, J. Julian Blow, Gareth H. Williams, Eward, Kathryn Leigh, Fanshawe, Thomas, Jung, HI, Shreeram, S., Prevost, Toby; id_orcid, Blow, J. Julian; id_orcid, A. Toby Prevost, Loddo, M, Williams, Gareth H., Thomas Fanshawe, Fanshawe, T, Obermann, Ellen C., Eward, KL, Williams, Gareth H, Jung, H-I, S. Shreeram, Blow, J Julian, Prevost, A. Toby, Stoeber, K, Stoeber, Kai, Blow, J. Julian, Prevost, AT, Blow, JJ, Craig Williams   +38 more
core   +1 more source

Homologous recombination, sister chromatid cohesion, and chromosome condensation in mammalian meiosis [PDF]

, 2002
In the life cycle of sexually reproducing eukaryotes, haploid and diploid generations of cells alternate. Two types of cell division occur in such a life cycle: mitosis and meiosis. They are compared in chapter 1 .
Eijpe, M.
core  

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

The cyclin-A CYCA1;2/TAM is required for the meiosis I to meiosis II transition and cooperates with OSD1 for the prophase to first meiotic division transition. [PDF]

PLoS Genetics, 2010
Meiosis halves the chromosome number because its two divisions follow a single round of DNA replication. This process involves two cell transitions, the transition from prophase to the first meiotic division (meiosis I) and the unique meiosis I to ...
Isabelle d'Erfurth, Laurence Cromer, Sylvie Jolivet, Chloé Girard, Christine Horlow, Yujin Sun, Jennifer P C To, Luke E Berchowitz, Gregory P Copenhaver, Raphael Mercier   +9 more
doaj   +1 more source

Cytological studies on meiosis and male gametophyte development in autotetraploid cucumber

, 2010
With improved staining and chromosome preparation techniques, meiosis of pollen mother cells (PMCs) and male gametophyte development in autotetraploid cucumber (Cucumis sativus L.) was studied to understand the correlation between chromosomes behaviour ...
C. -T. Qian, L. Cui, W. -P. Diao, J. -F. Chen, B. Jiang, S. -Y. Bao   +5 more
core   +1 more source

Super‐Multiplexed Label‐Free Raman Imaging Uncovers Novel Testicular Metabolic Couplings for Residual Body and Spermatogonial Differentiation

Advanced Science, EarlyView.
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li, Xia Chen, Yujuan Qi, Chen Qiao, Qiuru Huang, Dan Zhao, Weiyi Qian, Li Di, Yi Shi, Xiangqi Hu, Yueyue Shao, Kehan Wang, Zhiyu Tang‐Yang, Hanzhi Zang, Yuwen Du, Anran Dong, Jinxiong Feng, Jiayun Chen, Ying Zheng, Xiaofang Tan, Xiaoyu Zhao, Zhonghua Shi, Bo Zheng, Jun Yu   +23 more
wiley   +1 more source

Orchestrating homolog segregation in meiosis I: molecular logic and regulatory networks with emphasis on male metaphase I

Cell Communication and Signaling
Accurate segregation of homologous chromosomes during meiosis I (MI) is essential for haploid gamete production. This review systematically summarizes the dynamic regulatory mechanisms governing chromosome segregation in male mammalian meiosis.
Xinyu Zhang, Jiahao Liu, Kai Mao, Jingsheng Xu, Xiangyin Qian, Yao Rong, Tian Tian, Kai Wei, Minjie Chu, Yan Zhang   +9 more
doaj   +1 more source