Results 161 to 170 of about 39,650 (248)

Inhibition of late sodium current prevents pathological hyperactivation of calcium/calmodulin‐dependent protein kinase IIδ in a murine model of acute doxorubicin‐related cardiotoxicity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder, Anna‐Maria Pfützenreuter, Lea Maria Funke, Maria Johanna Baier, Daniel Tarnowski, Laura Stengel, Lars Siegfried Maier, Can Martin Sag   +7 more
wiley   +1 more source

Orthogonal Triple-Click Synthesis of Heteromimetic Triglycosylated Fullerenes. [PDF]

Org Lett
Nieto-Ortiz G, Patino-Alonso J, Honrubia-Rodríguez N, Martín N, Herranz MÁ, Illescas BM.   +5 more
europepmc   +1 more source

Targeted delivery of the CB2 receptor agonist JWH‐133 via VCAM‐1‐functionalised nanoparticles attenuates atherosclerosis and reveals sex‐specific therapeutic outcomes

British Journal of Pharmacology, EarlyView.
Background and Purpose Atherosclerosis, a chronic inflammatory disease characterised by lipid accumulation and endothelial dysfunction, remains a leading cause of cardiovascular morbidity and mortality. While cannabinoid 2 (CB2) receptor agonists show therapeutic promise in preclinical studies, their systemic application is hindered by poor ...
Lucía Martín‐Navarro, Lucía Martín‐Banderas, Josefa Álvarez‐Fuentes, María Dolores Herrera‐González   +3 more
wiley   +1 more source

From Furfural to Reprocessable Thermosets: Diels-Alder Monomers for Dynamic Polyurethane Networks. [PDF]

ChemSusChem
Galkin KI, Ananikov VP.
europepmc   +1 more source

Targeted keratin repair: A plant‐based approach to hair strength and surface restoration

International Journal of Cosmetic Science, EarlyView.
Application of Avena strigosa seed extract may reinforce keratin bonding, restoring hair fibre integrity by promoting intramolecular interactions at damaged sites of keratin proteins. Abstract Objective Chemical and thermal stress disrupts the intramolecular and intermolecular interactions that stabilize hair keratin, leading to structural degradation ...
Emina Besic Gyenge, Loya Schoeffel, Stefan Hettwer, Andreas Bosch, Cosimo Kropp, Brigit Suter, Barbara Obermayer   +6 more
wiley   +1 more source

Bacterial Display of Genetically Encoded Macrocyclic Peptide Libraries Using Cysteine-Reactive Unnatural Amino Acids. [PDF]

ACS Chem Biol
Dawodu O, Tharp JM.
europepmc   +1 more source

DNA‐Barcoded Polysaccharide Specific Monoclonal Antibodies Facilitate Sensitive and Multiplexed Detection of Cell Wall Polymers

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant cell walls are polysaccharide‐rich extracellular matrices composed of multiple complex carbohydrate polymer networks, including cellulose, hemicelluloses, pectins, and glycosylated proteins. Polysaccharide deposition critically impacts cell wall structure, and structural microheterogeneity within cell wall glycans also influences polymer
C. Frankie Griffith, Michael G. Hahn, Ian S. Wallace   +2 more
wiley   +1 more source

Apt19s-functionalized 3D-printed PCL/58S bioactive glass scaffolds <i>via</i> thiol-maleimide click chemistry enhance hBMSC adhesion and osteogenic differentiation. [PDF]

RSC Adv
Karimian S, Dini G, Nasri N, Najafabadi FM, Saharkhiz S.   +4 more
europepmc   +1 more source

Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang, Songhang Xing, Shanshan Zhang, Yuan Hao, Xiaojie Qu, Wurihan Bao, Manwei Hao, Han Sun, Mingyuan Dong, Huiling Zhang, Dan Huang, Yiqi Wang, Xuanjie Jiang, Xiaoyu Pu, Yanyan Chi, Xingtong Wang, Xuefeng Li   +16 more
wiley   +1 more source

Genetic Code Expansion Enables Oriented, Site-Specific Conjugation of DARPins to Lipid Nanoparticles for Selective mRNA Delivery to CD8⁺ T Cells. [PDF]

Int J Mol Sci
Dakhnevich A, Pateev I, Skvortsov IA, Yarmachkova S, Shevyrev D, Chubarova A, Gasina M, Cherepanova N, Siaglova ED, Reshetnikov V, Baranov MV, Ivanov RA.   +11 more
europepmc   +1 more source