Results 21 to 30 of about 175,504,466 (285)

MRI detection of mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE) on T1WI-CHESS. [PDF]

Epilepsy Behav Rep
Mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE) is a recently proposed epileptogenic entity that is difficult to detect on MRI. We present a case of MOGHE that was successfully detected on T1WI-chemical shift-selective
Arizono E, Tanei ZI, Iijima K, Kimura Y, Shigemoto Y, Maki H, Kusama M, Murayama K, Iwasaki M, Saito T, Saito Y, Saito K, Sato N.   +12 more
europepmc   +2 more sources

High-throughput, automated quantification of white matter neurons in mild malformation of cortical development in epilepsy [PDF]

, 2014
Introduction In epilepsy, the diagnosis of mild Malformation of Cortical Development type II (mMCD II) predominantly relies on the histopathological assessment of heterotopic neurons in the white matter.
Liu, J.Y.W., Ellis, M., Brooke-Ball, H., Brandner, S., de Tisi, J., Sisodiya, S.M., Eriksson, S.H., Thom, M.   +7 more
core   +4 more sources

Malformations of cortical development and epilepsy [PDF]

Dialogues in Clinical Neuroscience, 2008
Malformations of cortical development (MCDs) are an important cause of epilepsy and an extremely interesting group of disorders from the perspective of brain development and its perturbations. Many new MCDs have been described in recent years as a result of improvements in imaging, genetic testing, and understanding of the effects of mutations on the ...
Leventer RJ, GUERRINI, RENZO, Dobyns W.B.   +2 more
openaire   +8 more sources

Long-term outcome of the ketogenic diet for intractable childhood epilepsy with focal malformation of cortical development. [PDF]

, 2008
OBJECTIVE: We evaluated the efficacy and long-term outcome of the ketogenic diet in patients with intractable childhood epilepsy as a result of focal malformation of cortical development.
김흥동, D. E. Jung, Kang, HC, H. C. Kang, Kim, HD, Jung, DE, H. D. Kim   +6 more
core   +2 more sources

A human dynein heavy chain mutation impacts cortical progenitor cells causing developmental defects, reduced brain size and altered brain architecture

Neurobiology of Disease, 2023
Dynein heavy chain (DYNC1H1) mutations can either lead to severe cerebral cortical malformations, or alternatively may be associated with the development of spinal muscular atrophy with lower extremity predominance (SMA-LED). To assess the origin of such
Delfina M. Romero, Donia Zaidi, Carmen Cifuentes-Diaz, Camille Maillard, Gael Grannec, Mohammed Selloum, Marie-Christine Birling, Nadia Bahi-Buisson, Fiona Francis   +8 more
doaj   +1 more source

Surgical treatment of pediatric intractable frontal lobe epilepsy due to malformation of cortical development

Acta Epileptologica, 2022
Background Malformation of cortical development (MCD) is a common cause of intractable epilepsy in children. In this study, the effectiveness of frontal lobe epilepsy (FLE) surgery in children with intractable epilepsy due to MCD was assessed and its ...
Hao Yu, Qiang Lv, Qingzhu Liu, Shuang Wang, Taoyun Ji, Ruofan Wang, Wen Wang, Dongming Wang, Yuwu Jiang, Xiaoyan Liu, Lixin Cai   +10 more
doaj   +1 more source

The specific DNA methylation landscape in focal cortical dysplasia ILAE type 3D

Acta Neuropathologica Communications, 2023
Focal Cortical Dysplasia (FCD) is a frequent cause of drug-resistant focal epilepsy in children and young adults. The international FCD classifications of 2011 and 2022 have identified several clinico-pathological subtypes, either occurring isolated, i.e.
Dan-Dan Wang, Mitali Katoch, Samir Jabari, Ingmar Blumcke, David B. Blumenthal, De-Hong Lu, Roland Coras, Yu-Jiao Wang, Jie Shi, Wen-Jing Zhou, Katja Kobow, Yue-Shan Piao   +11 more
doaj   +1 more source

sj-docx-1-tan-10.1177_17562864211050027 – Supplemental material for Response to antiseizure medications in epileptic patients with malformation of cortical development

, 2021
Supplemental material, sj-docx-1-tan-10.1177_17562864211050027 for Response to antiseizure medications in epileptic patients with malformation of cortical development by Wei Chen, Bo Jin, Thandar Aung, Chenmin He, Cong Chen, Shan Wang, Yao Ding, Fang ...
Chenmin He (11563646), Haibin Dai (464649), Bo Jin (169366), Thandar Aung (11563643), Hong Li (20183), Wei Chen (23863), Junming Zhu (448145), Shuang Wang (46453), Cong Chen (325493), Yao Ding (1429924), Zhe Zheng (584306), Shan Wang (120085), Meiping Ding (113932), Fang Ding (222713), Yu Geng (592176), Chao Wang (146527), Biao Jiang (443263)   +16 more
core   +1 more source

Epileptogenic malformations of cortical development: when evolution goes awry

Acta Medica Lituanica, 2014
Background. Since the time of its origin in a mammalian ancestor, perhaps 250 million years ago, the neocortex has undergone expansion in both relative and absolute size.
Birutė Tumienė, Algirdas Utkus
doaj   +1 more source

Lissencephaly in Shih Tzu dogs

Acta Veterinaria Scandinavica, 2020
Background Lissencephaly is a brain malformation characterized by smooth and thickened cerebral surface, which may result in structural epilepsy. Lissencephaly is not common in veterinary medicine.
Diego Noé Rodríguez-Sánchez, Giovana Boff Araujo Pinto, Edval Fernando Thomé, Vânia Maria de Vasconcelos Machado, Rogério Martins Amorim   +4 more
doaj   +1 more source