Results 21 to 30 of about 20,100 (250)
Clinical and Genetic Spectrum of Tubulinopathy: A Single-Center Study [PDF]
Annals of Child NeurologyPurpose Tubulinopathy represents a group of disorders caused by variants in tubulin genes, which present with a wide spectrum of brain malformations. This study was conducted to provide insight into the phenotypic and genetic spectra of tubulinopathy ...
Hey-Joon Son +8 more
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Epileptogenic malformations of cortical development: when evolution goes awry
Acta Medica Lituanica, 2014 Background. Since the time of its origin in a mammalian ancestor, perhaps 250 million years ago, the neocortex has undergone expansion in both relative and absolute size.
Birutė Tumienė, Algirdas Utkus
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Pathology of surgically remediable epilepsy: How to evaluate
Indian Journal of Pathology and Microbiology, 2022 Epilepsy surgery is a well-established treatment modality in selected cases of medically refractory epilepsy. Advances in neuroimaging technology has greatly facilitated detection of lesions that are surgically amenable. Hippocampal sclerosis is the most
Rajalakshmi Poyuran
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Hippocampal Abnormalities with Cortical Malformations in Epilepsy Patients
Pediatric Neurology Briefs, 2010 The occurrence of various types and MRI appearance of hippocampal abnormalities in 220 patients with malformations of cortical development (MCD) were studied in various centers and large public hospital outpatient clinics in Germany and Austria.
J Gordon Millichap
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Genetics and Prenatal Injury in Cortical Malformations
Pediatric Neurology Briefs, 2002 The interrelationship of genetics and prenatal injury in the genesis of malformations of cortical development (MCD) was studied at the University of Campinas, SP, Brazil.
J Gordon Millichap
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The changing landscape in epilepsy imaging: Unmasking subtle and unique entities
Diagnostic and Interventional Radiology, 2022 Dramatic changes have occurred recently in the field of epilepsy, including a fundamental shift in the etiology of epileptogenic substrates found at surgery. Hippocampal sclerosis is no longer the most common etiology found at epilepsy surgery and this
Mehmet E. Adin +5 more
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Neurobiology of Disease, 2022 Objectives: Malformations of cortical development (MCDs) are common causes of drug-resistant epilepsy. The mechanisms underlying the associated epileptogenesis and ictogenesis remain poorly elucidated. EEG can help in understanding these mechanisms.
Lubna Shakhatreh +9 more
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Seizure Outcome after Hemispherectomy
Pediatric Neurology Briefs, 2001 MRI features of hemispheric malformations of cortical development (MCD) were correlated with post-hemispherectomy seizure outcome in 13 children treated at The Cleveland Clinic Foundation, OH.
J Gordon Millichap
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The Role of Prenatal Neurosonography in Identification of Tubulinopathy—Narrative Review
LifeTubulinopathies are severe, non-progressive neurodevelopmental disorders caused by mutations in tubulin genes, leading to profound intellectual disability, drug-resistant epilepsy, motor impairment, and lifelong dependence on care.
Krzysztof Berbeka +5 more
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Classification of Cortical Brain Malformations
Pediatric Neurology Briefs, 2008 Clinical, radiological, and genetic classifications of 113 cases of malformations of cortical development (MCD) were evaluated at the Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands.
J Gordon Millichap
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