Results 21 to 30 of about 174,337,571 (166)

Tubulin genes and malformations of cortical development [PDF]

European Journal of Medical Genetics, 2018
A large number of genes encoding for tubulin proteins are expressed in the developing brain. Each is subject to specific spatial and temporal expression patterns. However, most are highly expressed in post-mitotic neurons during stages of neuronal migration and differentiation.
Romaniello, R., Arrigoni, F., Fry, A. E., Bassi, M. T., Rees, M. I., Borgatti, R., Pilz, D. T., Cushion, T. D.   +7 more
core   +7 more sources

Malformations of cortical development: current concepts and advanced neuroimaging review

Arquivos de Neuro-Psiquiatria, 2011
Malformations of cortical development (MCD) result from disruptions in the complex process of the human brain cortex formation and are highly associated to severe epilepsy, neurodevelopmental delay and motor dysfunction.
Celi Santos Andrade, Claudia da Costa Leite   +1 more
doaj   +2 more sources

Predictors of Seizure Freedom After Surgery for Cortical Malformations

Pediatric Neurology Briefs, 2011
Researchers at the Northern California Epilepsy Center and University of California, San Francisco, conducted a retrospective review of 143 patients with malformations of cortical development (MCD) who underwent resection surgery for medically refractory
J Gordon Millichap
doaj   +2 more sources

Cognitive Outcome with Epilepsy and Malformations

Pediatric Neurology Briefs, 2000
To determine the relationship between malformations of cortical development and intellectual functioning (IQ), 54 children and adolescents with intractable epilepsy who later underwent cortical resection were studied at the Miami Children’s Hospital, FL.
J Gordon Millichap
doaj   +2 more sources

The clinical spectrum of malformations of cortical development Espectro clínico das malformações do desenvolvimento cortical

Arquivos de Neuro-Psiquiatria, 2007
BACKGROUND: Malformations of cortical development (MCD) usually manifest in childhood with epilepsy, developmental delay and focal neurological abnormalities. OBJECTIVE: To evaluate the presentation and severity of epilepsy in the different types of MCD.
Maria Augusta Montenegro, Fernando Cendes, Iscia Lopes-Cendes, Carlos A.M. Guerreiro, Li M. Li, Marilisa M. Guerreiro   +5 more
doaj   +5 more sources

Fetal malformations of cortical development: review and clinical guidance. [PDF]

Brain
Malformations of cortical development (MCDs) are a heterogeneous family of congenital brain malformations that originate from disturbed development of the cerebral cortex.
Russ JB, Agarwal S, Venkatesan C, Scelsa B, Vollmer B, Tarui T, Pardo AC, Lemmon ME, Mulkey SB, Hart AR, Nagaraj UD, Kuller JA, Whitehead MT, Cohen JL, Gebb JS, Glenn OA, Norton ME, Gano D.   +17 more
europepmc   +4 more sources

Malformations of Cortical Development

Brain Pathology, 2012
AbstractStructural abnormalities of the brain are increasingly recognized in patients that suffer from pharmacoresistant focal epilepsies by applying high‐resolution imaging techniques. In many of these patients, epilepsy surgery results in control of seizures.
Aronica, Eleonora, Becker, Albert J., Spreafico, Roberto   +2 more
  +6 more sources

Focal Cortical Dysplasia in Pediatric Epilepsy [PDF]

Annals of Child Neurology, 2019
Focal cortical dysplasia (FCD) is the most common cause of intractable focal epilepsy in children undergoing epilepsy surgery. In these patients, seizures usually develop in early childhood and are often explosive from their onset. This review summarizes
Sun Ah Choi, Ki Joong Kim
doaj   +1 more source

Neurodevelopmental Findings and Epilepsy in Malformations of Cortical Development. [PDF]

Turk Arch Pediatr, 2021
Aim: The purpose of this study is to classify the malformations of cortical development in children according to the embryological formation, localization, and neurodevelopmental findings. Seizure/epilepsy and electrophysiological findings have also been
Şah O, Türkdoğan D, Küçük S, Takış G, Asadov R, Öztürk G, Ünver O, Ekinci G.   +7 more
europepmc   +2 more sources

Malformations of Cortical Development [PDF]

The Neurologist, 2008
Malformations of cortical development (MCD) are increasingly recognized as an important cause of epilepsy and developmental delay. MCD encompass a wide spectrum of disorders with various underlying genetic etiologies and clinical manifestations. High resolution imaging has dramatically improved our recognition of MCD.This review will provide a brief ...
Trudy, Pang, Ramin, Atefy, Volney, Sheen
openaire   +2 more sources