Results 51 to 60 of about 174,337,571 (166)

Phosphorus magnetic resonance spectroscopy in malformations of cortical development

Arquivos de Neuro-Psiquiatria, 2013
IntroductionMalformations of cortical development (MCD) result from disruptions in the dynamic process of cerebral corticogenesis and are important causes of epilepsy, motor deficits and cognitive impairment.ObjectivesThe aim of this study was to ...
Celi Santos Andrade
doaj   +1 more source

Mapping the molecular and cellular complexity of cortical malformations [PDF]

, 2021
The cerebral cortex is an intricate structure that controls human features such as language and cognition. Cortical functions rely on specialized neurons that emerge during development from complex molecular and cellular interactions.
Jabaudon, D., Jabaudon, Denis, Klingler, Esther, Cappello, Silvia, Klingler, E., Francis, F., Cappello, S., Francis, Fiona, Fiona Francis, Silvia Cappello, Denis Jabaudon, Esther Klingler   +11 more
core   +1 more source

Malformações do desenvolvimento cortical em doentes com epilepsia. Estudo neuroimagiológico de 17 casos.

Acta Médica Portuguesa, 2001
This article reviews Malformations of Cortical Development (MCD) diagnosed by Magnetic Resonance Imaging (MRI) in a series of patients with epilepsy. This study spans a five year period. The frequency of these malformations was 7.1%.
S Carvalho, O Brito, E Machado, N Santos, P M Freitas, C Bento, I Santana, F Sales, F Martins   +8 more
doaj   +1 more source

Antisense Oligonucleotide Treatment for Focal Malformations of Cortical Development [PDF]

, 2022
Focal Malformations of Cortical Development (FMCD) are neurological developmental disorders that are a major cause of drug-resistant pediatric epilepsy.
Mittal, Swapnil
core   +1 more source

Cerebral activation in malformations of cortical development [PDF]

Brain, 1998
Malformations of cortical development (MCD) are an important aetiology of localization-related epilepsy. Previous MRI and [11C]flumazenil PET studies have demonstrated widespread structural and neuroreceptor abnormalities beyond the region of MCD that is visually apparent on MRI.
M P, Richardson, M J, Koepp, D J, Brooks, J T, Coull, P, Grasby, D R, Fish, J S, Duncan   +6 more
openaire   +2 more sources

Congenital pachygyria

Chinese Journal of Contemporary Neurology and Neurosurgery, 2016
Objective To investigate the imaging and clinicopathological features of pachygyria limited in the right temporo-parieto-occipital lobe and the key points of its diagnosis and treatment, in order to improve the recognition of this disease.
Jing-xia HU, Qiu-ping GUI, Wen-jing ZHOU, Mei-mei SUN, Jie LI, Xin SONG   +5 more
doaj  

The IL-1β system in epilepsy-associated malformations of cortical development

Neurobiology of Disease, 2006
Focal cortical dysplasia (FCD) and glioneuronal tumors (GNT) are recognized causes of chronic intractable epilepsy. The cellular mechanism(s) underlying their epileptogenicity remain largely unknown. Compelling evidence in experimental models of seizures
T. Ravizza, K. Boer, S. Redeker, W.G.M. Spliet, P.C. van Rijen, D. Troost, A. Vezzani, E. Aronica   +7 more
doaj   +1 more source

4E-BP1 expression in embryonic postmitotic neurons mitigates mTORC1-induced cortical malformations and behavioral seizure severity but does not prevent epilepsy in mice

Frontiers in Neuroscience, 2023
Hyperactivation of the mechanistic target of rapamycin complex 1 (mTORC1) pathway during neurodevelopment leads to focal cortical malformations associated with intractable seizures.
Lena H. Nguyen, Lena H. Nguyen, Manas Sharma, Angelique Bordey   +3 more
doaj   +1 more source

A report on gray matter heterotopias and neuropsychiatric manifestation: A bleary phenomenon

Archives of Mental Health
Malformations of the cortical system are associated with many neuropsychiatric manifestations. Gray matter heterotopia is a neuronal migration disorder characterized by the presence of normal gray matter neurons and glial cells, which are abnormally ...
Vishnupriya Veeraraghavan
doaj   +1 more source

Sonographic Cortical Development and Anomalies in the Fetus: A Systematic Review and Meta-Analysis

Biomedicines
The aim of this systematic review is to report the normal cortical development of different fetal cerebral fissures on ultrasound, describe associated anomalies in fetuses with cortical malformations, and evaluate the quality of published charts of ...
Ilenia Mappa, Daniele Di Mascio, Luigi Carbone, Jia Li Angela Lu, Sara Sorrenti, Chiara Patelli, Alice D’Amico, Barbara Matarrelli, Giulia Andrea Giuliani, Daniele Neola, Raffaella Di Girolamo, Laura Sarno, Asma Khalil, Giuseppe Rizzo, Giuseppe Maria Maruotti, Francesco D’Antonio   +15 more
doaj   +1 more source