Results 61 to 70 of about 174,337,571 (166)

Malformations Of Cortical Development.

, 2015
Malformations of cortical development (MCD) have been increasingly identified. The purpose of this presentation is to review the current knowledge of the MCD. Before we address this issue, we will briefly present a review of cortical development.
Guerreiro, Marilisa M
core  

Failure of antiepileptic drugs in controlling seizures in epilepsy: What do we do next?

Epilepsy and Behavior Case Reports, 2015
Medically intractable epilepsy is a clinical condition of concern that arises when a patient with epilepsy suffers seizures, despite a trial of two or more antiepileptic drugs (AEDs) suitable for the type of epilepsy that are prescribed at maximum ...
Brahyan Galindo-Mendez, Luis C. Mayor, Fernando Velandia-Hurtado, Carlos Calderon-Ospina   +3 more
doaj   +1 more source

Cerebral Volumetric Analysis Over Time in Children With Malformations of Cortical Development: A Quantitative Investigation

, 2010
Malformations of cortical development are common neurological disorders characterized by disruptions in the normal development of cerebral gray and white matter during fetal life.
Annapurna Poduri, Bernard S. Chang, Linsey M. Walker   +2 more
core   +1 more source

Malformations in cortical development in patients with epilepsy. Neuroimaging of 17 cases

, 2001
This article reviews Malformations of Cortical Development (MCD) diagnosed by Magnetic Resonance Imaging (MRI) in a series of patients with epilepsy. This study spans a five year period. The frequency of these malformations was 7.1%.
Santos, N, Brito, O, Bento, C, Machado, E, Santana, I, Martins, F, Sales, F, Carvalho, S, Melo Freitas, P   +8 more
core   +1 more source

Two uniqueTUBB3mutations cause both CFEOM3 and malformations of cortical development

, 2018
One set of missense mutations in the neuron specific beta tubulin isotype 3 (TUBB3) has been reported to cause malformations of cortical development (MCD), while a second set has been reported to cause isolated or syndromic Congenital Fibrosis of the ...
Tischfield, Max A., Grant, P., Whitman, Mary, Stasheff, Steven F., MacKinnon, Sarah E., Andrews, Caroline, Chan, Wai-Man, Engle, Elizabeth, Hunter, David, Ortiz-Gonzalez, Xilma, Garaci, Francesco, Brancati, Francesco, Nuovo, Sara   +12 more
core   +1 more source

CT Scan Data Analysis in Malformations of Cortical Development

Malformations of cortical development (MCDs) are a diverse group of disorders that result from abnormal neuronal migration, proliferation, and differentiation during brain development.
Scala M., Severino M.
core   +1 more source

Genetic Assessment of Cortical Malformations

, 2011
Malformations of cortical development comprise a clinically and etiologically heterogeneous group of distinct structural abnormalities of the cerebral cortex, commonly identified during MR imaging of patients with seizure disorders and/or developmental ...
G. Schuierer, Hehr, U., U. Hehr, Schuierer, G.   +3 more
core   +1 more source

Case reports: novel TUBG1 mutations with milder neurodevelopmental presentations

BMC Medical Genetics, 2019
Background Tubulinopathies result from mutations in tubulin genes, including TUBG1, responsible for cell microtubules, are characterized by brain development abnormalities, microcephaly, early-onset epilepsy, and motor impairment.
Yue T. K. Yuen, Ilaria Guella, Elke Roland, Michael Sargent, Cyrus Boelman   +4 more
doaj   +1 more source

MRI-based spectral analysis of fetal brain gyrification in typical development and in lissencephaly and polymicrogyria

Scientific Reports
Cortical gyrification is a key marker of fetal brain development and is typically assessed qualitatively on ultrasound or MRI. While previous quantitative approaches have characterized gestational trajectories in typically developing (TD) fetuses, only a
Bossmat Yehuda, Rotem Gal, Yair Wexler, Aviad Rabinowich, Elka Miller, Liat Ben Sira, Dafna Ben Bashat   +6 more
doaj   +1 more source

Congenital Bilateral Perisylvian Syndrome Associated with Pierre Robin Sequence: a Case Report

Iatreia
Introduction: Pierre Robin sequence is characterized by the classic triad of congenital micrognathia, glossoptosis, and airway obstruction. It is caused by various etiologies, including cortical development malformations as seen in congenital perisylvian
Castro-Murillo, Julio Cesar , Gómez-Guzmán, Enid Leticia, Rojas-Cerón, Christian Andrés   +2 more
doaj   +1 more source