Results 101 to 110 of about 38,142 (215)
International Journal of Cancer, Volume 159, Issue 4, Page 1005-1016, 15 August 2026.Glioblastoma (GBM) is highly aggressive and therapy‐resistant, warranting exploration of novel treatment strategies, among them mechanical high‐intensity focused ultrasound (mFUS), which holds significant promise for tumor ablation. The present study examined mFUS‐induced changes specifically in carbohydrate metabolism, which affects vulnerability to ...
Frieda Bayler +10 more
wiley +1 more source
Advanced Science, Volume 13, Issue 35, 24 June 2026.Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Malignant Hyperthermia - the Hidden Danger
, 2017 Introduction: Malignant hyperthermia (MH) is a life-threatening elevation in body temperature usually resulting from a hypermetabolic response to concurrent use of a muscle relaxant and an inhalational general anesthetic.
Angelov, Plamen +4 more
core +1 more source
Advanced Science, Volume 13, Issue 35, 24 June 2026.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source
Porcine malignant hyperthermia during sevoflurane anaesthasia
, 2017 During a surgical procedure, in a pig, under general anaesthesia with sevoflurane, the animal developed malignant hyperthermia. Malignant hyperthermia was expressed only by a progressive increase of rectal temperature without early symptoms from the ...
P. ALEXAKOS (Π. ΑΛΕΞΑΚΟΣ) +5 more
core +1 more source
Advanced Science, Volume 13, Issue 31, 4 June 2026.The novel intravesical delivery system exhibits GSH‐responsive drug release, enabling a synergistic therapeutic strategy that combines ferroptosis, ICD and PTT. ABSTRACT Ferroptosis, a newly recognized form of regulated cell death, has emerged as a promising strategy in cancer therapy.
Xiaojian Xu +15 more
wiley +1 more source
Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology
Advanced Science, Volume 13, Issue 33, 15 June 2026.Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu +4 more
wiley +1 more source
ChemNanoMat, Volume 12, Issue 6, June 2026.Stimuli‐responsive strategies to achieve controlled release of protein‐based therapeutic agents into solid tumors. Proteins, enzymes, and peptides have long been recognized as valuable therapeutic agents, particularly in oncology. However, their complex chemical structures render them more sensitive than smaller chemotherapeutic drugs.
Guillermo Plaza‐Palomo +3 more
wiley +1 more source
Inducible CRISPR/Cas systems in precision oncology: Current applications and future perspectives
Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.Inducible CRISPR/Cas systems enable spatiotemporal genome editing in precision oncology. Chemical, optical, physical, and microenvironmental stimuli provide distinct control strategies. Conditional activation may reduce off‐target exposure and basal nuclease activity.
Ziliang Ding +3 more
wiley +1 more source