Results 121 to 130 of about 57,983 (265)

Ultrasound‐Responsive Engineered Bacteria for Targeted Cancer Therapy: Strategies, Mechanisms, and Applications

Advanced Science, Volume 13, Issue 20, 9 April 2026.
This review elucidates URB design strategies, including genetic and physicochemical modifications, while dissecting the synergistic mechanisms governing spatiotemporal control. It further evaluates applications in targeted drug delivery, gene modulation, and immunotherapy, finally offering perspectives on overcoming translational barriers for clinical ...
Xueyao Wang, Wenjing Xu, Yafang Lu, Huaibin Yu, Zhengbao Zha, Xijun Zhang   +5 more
wiley   +1 more source

PLASMA CHOLINESTERASE AND MALIGNANT HYPERTHERMIA

, 1981
Helle Ørding, HENRIK H. HANEL, J. Viby‐Mogensen   +2 more
openalex   +2 more sources

The Use of a Platelet Nucleotide Assay as a Possible Diagnostic Test for Malignant Hyperthermia [PDF]

, 1985
M. B. Lee, Michael G. Adragna, Leila Edwards   +2 more
openalex   +1 more source

The neuromuscular and multisystem features of RYR1-related malignant hyperthermia and rhabdomyolysis

, 2021
Luuk R. van den Bersselaar, Nick Kruijt, Gert‐Jan Scheffer, Lucas van Eijk, Ignacio Malagon, Stan Buckens, José A. E. Custers, Leonie Helder, Anna Greco, Leo A. B. Joosten, Baziel G.M. van Engelen, Nens van Alfen, Sheila Riazi, Susan Treves, Heinz Jungbluth, Marc Snoeck, Nicol C. Voermans   +16 more
openalex   +1 more source

Dantrolene Available in China for Malignant Hyperthermia Treatment [PDF]

, 2021
Zhengqian Li, Kaixi Liu, Xiangyang Guo
openalex   +1 more source

Recent Advances in Tetrahedral Framework Nucleic Acids for Multimodal Synergistic Cancer Therapy

Aggregate, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in tFNA‐based multimodal cancer therapy, including structural features, delivery strategies, and therapeutic regimens addressing key challenges in cancer treatment. We outline design principles, address translational hurdles, and highlight intelligent response and immune regulation as promising directions to ...
Zishan Huang, Zhitong Chen, Zhiyu Zhang, Hong Sun, Xujuan Li, Zhaogang Sun, Hongqian Chu, Wenjing Liu   +7 more
wiley   +1 more source

Effects of a novel RyR1 inhibitor on malignant hyperthermia model mice

, 2020
Takashi Murayama, Toshiko Yamazawa, Takuya Kobayashi, Nagomi Kurebayashi, S. Noguchi, Ichizo Nishino, Shuichi Mori, Hiroyuki Kagechika, José R. López, Paul D. Allen, Takashi Sakurai   +10 more
openalex   +2 more sources

Blood–Brain Barrier: Structure, Function, Diseases, and Drug Delivery Systems

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract illustrates how blood–brain barrier‐targeted nanomedicine integrates diverse nanocarrier platforms with mechanism‐based therapeutic strategies to overcome delivery barriers in ischemic stroke, enabling targeted modulation of oxidative stress, inflammation, excitotoxicity, and neuronal survival.
Yanan He, Mengyao Qu, Lu Yu, Lipeng He, Yixun Lu, Jin Hong, Miao Sun, Huikai Yang, Weidong Mi, Hang Guo, Yulong Ma   +10 more
wiley   +1 more source

Hyperthermia as an Antineoplastic Treatment Modality [PDF]

Preclinical evaluation of hyperthermia for treating tumerous cancers is ...
El-Mahdi, Anas M., Long, Sheila Ann T., Shaeffer, James   +2 more
core   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, Volume 15, Issue 4, April 2026.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source