Results 51 to 60 of about 5,053 (210)

Pseudotetraivprolides from Pseudomonas entomophila Provide Insights into the Biosynthesis of Detoxin/Rimosamide‐Like Anti‐Antibiotics

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 4, 22 January 2026.
Pseudotetraivprolide is a new player among the Detoxin/Rimosamide‐like natural products! Its biosynthesis requires FabD from primary metabolism and a PipDFG complex for final‐step acetylation – unlocking its anti‐antibotic activity. Abstract Novel variants of known natural product (NP) classes can provide valuable insights into their biosynthesis ...
Edna Bode   +13 more
wiley   +1 more source

Mesoionic N‐Heterocyclic Olefins, Imines, Thiones, Phosphinidenes and Their Application in Catalysis

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 3, 16 January 2026.
This minireview covers recent advances in the synthesis, reactivity, and metal‐free catalytic uses of mesoionic N‐heterocyclic olefins (mNHOs), imines (mNHIs), thiones (mNHTs), and phosphinidenes (mNHPs). Abstract Transition metal compounds are widely known for their ability to activate small molecules and are excellent catalysts for a wide range of ...
Subir Maji   +3 more
wiley   +1 more source

Cyclopropenes in Photochemical Reactions

open access: yesChemistry – A European Journal, Volume 32, Issue 3, 16 January 2026.
The photochemical side of cyclopropenes. Cyclopropenes are valuable synthetic tools in organic chemistry. In particular, this review focuses on the photochemistry of cyclopropenes. The reactivity of cyclopropenes excited by irradiation is discussed showing their unique potential for organic synthesis.
David Suárez‐García   +2 more
wiley   +1 more source

Hoveyda–Grubbs 1st and 2nd Generation Precatalysts Modified in the Alkoxybenzylidene Part With Long (Fluorous) Chains: Catalytic Activity and Stability

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 2, January 16, 2026.
We synthesized a series of light to heavy fluorous Hoveyda–Grubbs precatalyst analogs modified in the alkoxybenzylidene part in positions 2 and 5 by long (fluorinated) ponytails and tested their activity in ring‐closing metathesis. The substitution mostly resulted in accelerated reaction but the precatalyst stability often decreased.
Pavlína Dundálková   +4 more
wiley   +1 more source

Design eines aus der Fettsäuresynthase der Maus abgeleiteten Multienzyms für die kompartimentierte chemo‐enzymatische Synthese von 2‐Pyron‐Polyketiden

open access: yesAngewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Die 4‐Cumarate‐Ligase (4CL1) aus Piper methysticum wurde mit einer nicht‐reduzierenden murinen Fettsäuresynthase verknüpft. Eine direkte Acylierung des ACP durch 4CL1 wurde beobachtet. Die Ketosynthase (KS) wurde so verändert, dass sie das nicht‐kanonische Zimtsäure‐Substrat akzeptiert.
Felix Lehmann   +3 more
wiley   +1 more source

Crystal structure of diethyl 2-[(2-sulfanylquinolin-3-yl)methylidene]malonate [PDF]

open access: gold, 2015
Rihanabanu   +4 more
openalex   +1 more source

Design of a Multienzyme Derived from Mouse Fatty Acid Synthase for the Compartmentalized Production of 2‐Pyrone Polyketides

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 2, 9 January 2026.
A multienzyme was formed and evaluated by covalently linking 4‐coumarate ligase (4CL1) from Piper methysticum to a non‐reducing murine fatty acid synthase. 4CL1 acylates the acyl carrier protein (ACP). The ketosynthase (KS) was engineered to accept the non‐native cinnamoyl substrate, which is elongated by malonyl‐CoA loaded via the malonyl‐acetyl ...
Felix Lehmann   +3 more
wiley   +1 more source

Crystal structure of bis(4-methoxyphenyl) malonate [PDF]

open access: gold, 2015
H.C. Devarajegowda   +4 more
openalex   +1 more source

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