Results 121 to 130 of about 180,373 (302)
Advanced Science, EarlyView.An inhalable, nanoengineered herbal therapy achieves protection against acute radiation‐induced lung injury via self‐assembled nanomicelle‐mediated pulmonary targeting and a previously unrecognized dual mechanism that attenuates oxidative stress while inhibiting ferroptosis in alveolar epithelial cells.
Li Quan +11 more
wiley +1 more source
Advanced Science, EarlyView.Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen +11 more
wiley +1 more source
Advanced Science, EarlyView.Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai +12 more
wiley +1 more source
Reaction of Malondialdehyde with Deoxyribonucleosides in the Presence of Acetaldehyde.
Biological and Pharmaceutical Bulletin, 1994 The reactivity of malondialdehyde (MDA) with deoxyribonucleosides in the presence of acetaldehyde (AA) was investigated. Although MDA is known to be reactive towards deoxyguanosine (GdR), deoxyadenosine (AdR) and deoxycytidine (CdR) under acidic conditions, MDA had only slight reactivity towards GdR under physiological pH. However, when AA was present,
openaire +3 more sources
Advanced Science, EarlyView.Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao +6 more
wiley +1 more source
Effect of different concentrations of melatonin on malondialdehyde (MDA) content.
, 2019 Effect of different concentrations of melatonin on malondialdehyde (MDA) content.
Hongchun Sun (5211020) +8 more
core +1 more source
Advanced Science, EarlyView.A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou +12 more
wiley +1 more source
Revista Ciencias de la Salud, 2012 It is believed that mercury neurotoxicity is due to induction of oxidative stress [as determinedby increased concentrations of malondialdehyde (MDA)], but we don’t know if to have higherconcentrations of MDA involves to have more neurological disorders ...
Arroyave-Hoyos Claudia Lucía +4 more
doaj
, 2009 Substantial quantities of glutamate and reactive oxygen species are released following neurotraumas. Present work establishes that administering glutamate into the spinal cord at the level at which it is released following spinal cord injury did not ...
梁振, 张玉奎, 单亦初, 张丽华
core