Results 31 to 40 of about 99,209 (245)

Effect of combined mesenchymal stem cell and derived exosomes in control of STZ induced diabetic hepatopathy in Wistar rat model [PDF]

Veterinary Medical Journal - Giza
Diabetes mellitus (DM) is a chronic widespread metabolic disorder, involving a high blood glucose level which causes overtime multiple serious complications.
Rehab Khereldin, Yara Abouelela, Fady Youssef, Adel Tohamy, Hamdy Rizk, Samer Daghash   +5 more
doaj   +1 more source

Effect of Amlodipine on Malondialdehyde (MDA) in Hypertensive Patients

Kushtia Medical College Journal
Background: Hypertension (HTN) is an important public health problem due to its complications and is associated with oxidative stress. This study was designed to compare the level of Malondialdehyde (MDA) among the normal individuals, newly diagnosed hypertensive patients and hypertensive patients receiving Calcium channel blocker (amlodipine ...
Monjila Khatun, Md Shumsuzzaman, Mst Shakila Parvin, Mst Arifa Shirin   +3 more
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Study of level of malondialdehyde and total antioxidant capacity (TAC) in human lens epithelial cells of diabetic and senile cataract patients

Advances in Medical, Pharmaceutical and Dental Research, 2023
Background: Oxidative stress is a condition where the balance between the production and elimination of reactive oxygen species (ROS) is disturbed. ROS can cause damage to various biomolecules, including DNA.
Kranti Santosh Sorte Gawali, Avinash Namdeo Jadhao   +1 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Increased Blood Concentrations of Malondialdehyde in Plasmodium Infection: A Systematic Review and Meta-Analysis

Antioxidants, 2023
Several studies have evaluated the relationship between malondialdehyde (MDA) concentrations and Plasmodium infections; however, the findings remain inconclusive.
Onchuma Mueangson, Aongart Mahittikorn, Nsoh Godwin Anabire, Wanida Mala, Manas Kotepui   +4 more
doaj   +1 more source

Effect of Losartan on Malondialdehyde (MDA) in Hypertensive Patients

TAJ: Journal of Teachers Association
Background: Hypertension (HTN) is an important public health problem due to its complications. HTN is associated with oxidative stress. This study was designed to compare the level of MDA among the normal individuals, newly diagnosed hypertensive patients and hypertensive patients on treatments.
Monjila Khatun, null Sabiha Yasmin Moni, null Shumsuzzaman Konok, null Sonia Nilufar   +3 more
openaire   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Determination of oxidative stress level and some antioxidant activities in refractory epilepsy patients

Scientific Reports
The aim of this study was to determine the levels of superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and malondialdehyde (MDA) in patients with refractory epilepsy.
Abdullah Yilgor, Canan Demir
doaj   +1 more source

PEMBERIAN EKSTRAK ETANOL KUBIS UNGU (Brassica Oleracea Var. Capitata L.) MENYEBABKAN KADAR MALONDIALDEHID MENJADI RENDAH DAN KADAR SUPEROKSIDA DISMUTASE MENJADI TINGGI PADA TIKUS GALUR WISTAR JANTAN (Rattus Norvegicus) YANG DIBERI LATIHAN FISIK MAKSIMAL

Jurnal Ilmiah Medicamento, 2020
Aktivitas fisik maksimal memicu terjadinya peningkatkan produksi peroksidasi lipid yang ditandai dengan terbentuknya malondialdehyde (MDA) dan dapat menurunkan aktivitas enzim superoksida dismutase (SOD).
Fadli, I Putu Gede Adiatmika, I Ketut Tirtayasa   +2 more
doaj