Results 131 to 140 of about 72,918 (250)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, Volume 20, Issue 8, Page 1986-2007, August 2026.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

open access: yesAdvanced Science, Volume 13, Issue 44, 7 August 2026.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang   +17 more
wiley   +1 more source

Combined Effects of Algae‐Supplemented Feeding Regimes and Water Temperature on Sperm Quality of Common Carp (Cyprinus carpio) Broodstock During Spawning

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 4, August 2026.
ABSTRACT This exploratory study investigated associations between dietary algae supplementation (1% and 3%) and sperm quality in male common carp (Cyprinus carpio) broodstock during two consecutive spawning seasons under commercial farming conditions. Sperm quality was evaluated using conventional motility and kinetic parameters together with analyses ...
Gergely Bernáth   +22 more
wiley   +1 more source

Comparative functional genomics of <i>Saccharomyces cerevisiae</i> reveals genetic determinants of stress tolerance and ethanol fermentation. [PDF]

open access: yesMicrobiol Spectr
Han Y   +9 more
europepmc   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

open access: yesAnimal Research and One Health, Volume 4, Issue 3, Page 278-292, August 2026.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou   +4 more
wiley   +1 more source

Dynamic, Unconstrained Optimization of Secreted Enzyme Production in Fed‐Batch Fermentation Using Reinforcement Learning

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 8, Page 2024-2036, August 2026.
ABSTRACT Reinforcement learning (RL) has been used to control a wide range of dynamic processes, especially ones that are too complex to model well or have stochastic environmental perturbations. Fed‐batch fermentations are subject to changes in starting cell growth rates and process variations that can affect cell growth and secreted target production.
Sai Harish Uthravalli   +3 more
wiley   +1 more source

Lineage-Specific Adaptive Strategies Shape the Response of de Novo Lager Yeast Hybrids to High-Gravity Fermentation. [PDF]

open access: yesMicrob Biotechnol
Albillos-Arenal S   +6 more
europepmc   +1 more source

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