Results 101 to 110 of about 374,047 (298)

Capture and Culture of Circulating Tumor Cells Using a Biodegradable 3D Scaffold for Patient‐Derived Xenograft Construction

Advanced Science, EarlyView.
A self‐supporting, biocompatible, and biodegradable 3D cellulose scaffold has been developed for efficient isolation and in situ expansion of circulating tumor cells (CTCs) from patient blood. Subsequently, the 3D cellulose scaffold with cultured CTCs is directly implanted into immunodeficient mice for constructing patient CTC‐derived xenograft (CDX ...
Yi‐Ke Wang, Ming Wang, Min Liu, Yi‐Jing Chen, Li‐Li Xu, Jin‐Ping Zhou, Fu‐Bing Wang, Shi‐Bo Cheng, Min Xie, Wei‐Hua Huang   +9 more
wiley   +1 more source

"518 años de resistencia, 200 años de lucha de los pueblos". El deber, el derecho de re-existencia y libertad.

Maguaré, 2010
Desde hace millones de años los pueblos originarios existíamos en el gran continente del Abya Yala, en donde no existían banderas de separación, no habían himnos de división, no habían fronteras que nos alejen, teníamos acceso a los dos mares: Atlántico ...
Jeremías Tunubalá, Liliana Pechené Muelas   +1 more
doaj   +2 more sources

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Is Black Motherhood A Marker of Oppression or Empowerment? Hip-Hop and R&B Lessons about Mama [PDF]

, 2015
A qualitative content analysis was conducted on the lyrics of 59 songs (40 Hip Hop songs; 17 R&B songs; 2 songs that represented the Hip Hop and R&B genre) from 1961-2013 to identify the ways that Black male and Black female artists described motherhood.
Brown, Arielle, Chaney, Cassandra
core   +3 more sources

Beyond Catalytic Therapy: Copper‐Paeonol Nanozymes Disrupt Fascin‐Mediated Actin Bundling to Suppress Tumor Growth and Metastasis

Advanced Science, EarlyView.
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang, Huajun Li, Yisen Wang, Jie Xiang, Lei Fan, Shengzhe Zhang, Lizeng Gao, Hua Dai, Juqun Xi   +8 more
wiley   +1 more source

Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

Advanced Science, EarlyView.
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim, Ha Kyeong Lee, Zulfikar Azam, Jeong Uk Choi, Riajul Wahab, Na Kyeong Lee, Yoon Gun Ko, So‐Young Choi, Se‐Ra Lee, Wan Seob Shim, Taeeung Kim, In‐San Kim, Farzana Alam, Sang Yoon Kim, Seong Who Kim, Youngro Byun, Taslim A Al‐Hilal   +16 more
wiley   +1 more source

Cancer Health Disparities Among Patients With Early-Stage Estrogen Receptor–Positive Breast Cancer: Impact of Public Versus Private Health Care on Diagnosis-to-Treatment Interval in Brazil

JCO Global Oncology
PURPOSEIn 2013, Brazil implemented a federal law (Law 12.732/2012) mandating cancer treatment to begin within 60 days of diagnosis. Among women with newly diagnosed estrogen receptor–positive (ER+) nonmetastatic breast cancer, we describe the diagnosis ...
Romualdo Barroso-Sousa, Danielle Laperche-Santos, Heloisa Resende, Fernanda Cesar Moura, Sulene Cunha Sousa Oliveira, Andrea Kazumi Shimada, Renata Arakelian, Anna Luiza Zapalowski Galvão, Bruno Santos Wance de Souza, Amanda Guimarães Castro Custodio, Monalisa Ceciliana Freitas Moreira de Andrade, Yuri Cardoso Rodrigues Beckedorff Bittencourt, Maria Cristina Figueroa Magalhães, Cristiano de Pádua Souza, Carlos Eduardo Paiva, Poliana Albuquerque Signorini, Daniela Jessica Pereira, Angélica Nogueira-Rodrigues, Daniela Dornelles Rosa, Brittany Bychkovsky, Daniele Assad-Suzuki   +20 more
doaj   +1 more source

"Goldilocks and the Three Bears" [PDF]

Unlike the Papa, Mama, and Baby Bears faced by the storybook Goldilocks, our Goldilocks faced three ferocious grizzlies: a cascading, global financial crisis; global deflation and excess capacity (or insufficient demand); and a domestic fiscal surplus in
L. Randall Wray
core  

August Wilson’s The Piano Lesson and the Limits of Law [PDF]

, 2008
August Wilson’s The Piano Lesson features a debate between an African American brother and sister over the ownership of a richly symbolic piano, a family heirloom that represents the Charles family’s slave heritage and its endurance through ...
Benoit, Emilie, Tackach, James
core   +1 more source

The Nearby Neutron Star RX J0720.4-3125 from Radio to X-rays

, 2003
We present radio, optical, ultraviolet, and X-ray observations of the isolated, thermally-emitting neutron star RX J0720.4-3125 using the Parkes radio telescope, the Very Large Array, the Hubble Space Telescope, and the Chandra X-ray Observatory.
B. A. Jacoby, Becker W., Bessell M. S., D. A. Frail, D. L. Kaplan, H. L. Marshall, Haberl F., M. H. van Kerkwijk, Motch C., Predehl P., S. R. Kulkarni, Seiradakis J. H., Stys D. J.   +12 more
core   +1 more source