Results 41 to 50 of about 37,085 (301)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Appropriation des nouvelles médiations technopédagogiques. Enjeux, contraintes et perspectives pour une éducation de qualité pour tous en Afrique

open access: yesÉducation et Socialisation, 2023
Africa is facing certain difficulties that compromise the accessibility of educational services. The New techno-pedagogical mediations (NTM), which have emerged as an alternative training method adapted to these emergency educational situations, are ...
Mama Chandini
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Propiedades Psicométricas del Cuestionario de Motivos a Favor y en Contra de la Reconstrucción Mamaria

open access: yesPsicooncologia, 2019
Antecedentes: Aunque la reconstrucción mamaria (RM) tras la mastectomía es una opción estética con buenos resultados, se realiza poco en México. Para estudiar sus razones se creó el Cuestionario de Motivos a favor y en contra de la Reconstrucción Mamaria
José Moral de la Rubia   +3 more
doaj   +1 more source

Modernization of Mali’s investment policy in the context of improving the sustainable development strategy

open access: yesRUDN Journal of Economics, 2023
Since 2012, the Republic of Mali has been facing numerous security challenges caused by the separatist uprising led by the National Movement for the Liberation of Azawad and many non-State armed groups. This led to a loss of control by the authorities in
Mama Dembele
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Dose dense versus 3 weekly AC during neoadjuvant chemoimmunotherapy for triple negative breast cancer

open access: yesnpj Breast Cancer
Neoadjuvant pembrolizumab plus chemotherapy (P + CT) has emerged as a standard of care for stage II-III triple-negative breast cancer (TNBC). However, the best anthracycline-cyclophosphamide (AC) schedule remains to be determined.
Renata Colombo Bonadio   +22 more
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Avaliação da dissecção axilar na mastectomia radical modificada a Madden para o tratamento do câncer mamário

open access: yesRevista Brasileira de Cancerologia, 2023
Com o objetivo de analisar o número de linfonodos dissecados, foram estudados 229 pacientes portadoras de câncer de mama, tratadas no Hospital Araújo Jorge entre 1979 e 1988.
Geraldo S. Queiroz   +7 more
doaj   +1 more source

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