Human breast organoid models for lactation research
Reproduction and Breeding, 2023 The human mammary gland is the major organ involved in lactation. In the mammary gland, alveoli secrete milk and myoepithelial cells contract to propel the milk through branched structures called ducts and eventually to the nipple.
Jenny Lee +4 more
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Stromal fibroblastic mutant Trp53 promotes mammary tumor development via enhanced secretion of paracrine factors. [PDF]
NPJ Breast CancerMutations in the tumor suppressor gene TP53 have been identified in breast cancer-associated fibroblasts and are associated with poor patient prognosis.
Liu B +12 more
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Canine Mammary Gland Cancer Stem Cell and its Potential Role in Malignant Biologic Behavior [PDF]
Iranian Journal of Veterinary Medicine, 2020 BACKGROUND:Canine mammary gland cancers are the most prevalent malignancies in dogs. There are different challenges regarding management of these cancers in dogs and human, one hypothesis is related to small cellular subset of tumor mass called cancer ...
Havva Marzban, Farhang Sasani
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Effects of age and parity on mammary gland lesions and progenitor cells in the FVB/N-RC mice. [PDF]
PLoS ONE, 2012 The FVB/N mouse strain is extensively used in the development of animal models for breast cancer research. Recently it has been reported that the aging FVB/N mice develop spontaneous mammary lesions and tumors accompanied with abnormalities in the ...
Ahmed Raafat +8 more
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The Presence and Distribution of TRPM7 in the Canine Mammary Glands
Animals, 2020 The transient receptor potential melastatin-subfamily member 7 (TRPM7) cation channel is a bifunctional ion channel with intrinsic kinase activity and is ubiquitously expressed in the animal/human body.
Sungin Lee +6 more
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Down-expression of klotho in canine mammary gland tumors and its prognostic significance
PLoS ONE, 2022 Since the discovery of klotho as an anti-aging gene, its association with tumors has been studied. Several previous studies have reported the down-expression of klotho in various human cancers, and much of its mechanism has been revealed.
Heaji Chung +3 more
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B-mode and Doppler ultrasound features of mammary neoplasms and their comparison with normal mammary glands in dogs [PDF]
Journal of Veterinary and Animal Sciences, 2022 Canine mammary neoplasms are naturally occurring non-homogenous group of tumours with many resemblances to human breast cancer. In female dogs mammary tumours are of great clinical relevance due to the high prevalence and mortality rate, which varies ...
Aleena Thomas +6 more
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Preparation of Single Epithelial Cells Suspension from Mouse Mammary Glands
Bio-Protocol, 2020 Single cell RNA sequencing is a very powerful means for cellular heterogeneous studies and so becoming wildly utilized nowadays. To guarantee the success of such analysis, it is very important, though sometimes difficult, to obtain single cells ...
Heng Sun, Xiaoling Xu, Chuxia Deng
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Effects of ethanol extract of curry leaves (Murraya koenigii) on HER2 and caspase-3 expression in rat model mammary carcinoma [PDF]
Veterinary World, 2021 Background and Aim: Human epidermal growth factor receptor 2 (HER2/erbB2/neu) is a prognostic factor and biomarker for detecting mammary tumor malignancy.
Siti Aisyah +3 more
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Productive Infection of Mouse Mammary Glands and Human Mammary Epithelial Cells by Zika Virus
Viruses, 2019 Zika virus (ZIKV) belongs to the large category of arboviruses. Surprisingly, several human-to-human transmissions of ZIKV have been notified, either following sexual intercourse or from the mother to fetus during pregnancy. Importantly, high viral loads
Mathieu Hubert +7 more
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