Results 141 to 150 of about 218,839 (237)

Loss of BPTF restores estrogen response and suppresses metastasis of mammary tumors. [PDF]

Nat Commun
Ciccone MF, Anandan D, Chatterjee D, Chen C, Trousdell MC, Anderson R, Lewis SM, Callaway MK, Zhao CZ, Hanasoge Somasundara AV, Russo S, Yang ST, Zhao Y, Ostrander J, Wilkinson JE, Pomerantz WCK, Siepel A, Spector DL, Tollkuhn J, Dos Santos CO.   +19 more
europepmc   +1 more source

Delivering precision oncology in metastatic breast cancer: Clinical impact of comprehensive genomic profiling—The CATCH experience

International Journal of Cancer, Volume 158, Issue 6, Page 1675-1689, 15 March 2026.
What's new? CATCH is a prospective precision oncology registry trial that harnesses whole‐genome/exome‐ and RNA‐sequencing to enable actionable biomarker detection in metastatic breast cancer patients of any subtype. The data of the first 412 consecutive patients with completed follow‐up in this real‐world, single‐center patient cohort provide robust ...
Mario Hlevnjak, Sabine Heublein, Verena Thewes, Lukas Wagener, Constantin Pixberg, Carlo Fremd, Laura Michel, Christian Maurer, Lars Buschhorn, Nicola Dikow, Fangyoumin Feng, Stefan Fröhling, Christel Herold‐Mende, Steffen Hirsch, Chen Hong, Daniel Hübschmann, Lena Jassowicz, Polina Kozyulina, Katrin Pfütze, Richard F. Schlenk, Hans‐Peter Sinn, Katharina Smetanay, Christoph Springfeld, Albrecht Stenzinger, Celina Wagner, Stephan Wolf, Andreas Trumpp, Dirk Jäger, Oliver Zivanovic, Marc Zapatka, Andreas Schneeweiss, Peter Lichter   +31 more
wiley   +1 more source

Non-redundant roles of the phosphoinositide phosphatases PTEN and PIPP in PI3K/AKT signaling in breast cancer. [PDF]

Commun Biol
Ooms LM, Ferguson DT, Rodgers SJ, Sukhija KK, Jones EI, Csolle MP, Yip HYK, Daly RJ, Tiganis T, McLean CA, Papa A, Mitchell CA.   +11 more
europepmc   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

The influence of two neurohormones on breast cancer: prolactin and melatonin. [PDF]

Rev Assoc Med Bras (1992)
Ferreira CDS, Carvalho KC, Ferreira IDS, Cavalcanti GS, Cipolla Neto J, Zambotti PEO, Baracat EC, Soares Junior JM.   +7 more
europepmc   +1 more source

Probing the Influence of Paternal Diet on Offspring Neuroanatomy With Mouse MRI

Brain and Behavior, Volume 16, Issue 2, February 2026.
This study aimed to determine if paternal consumption of a high‐fat/high‐simple‐sugar (HF/HSS) diet prior to conception recapitulates the offspring brain structure volume changes seen with parental preconception consumption of an HF/HSS diet. Using C57Bl6/J mice and MRI, we established that there were no significant effects of paternal HF/HSS eating ...
Emma G. W. McKnight, Gail Lee, Cheryl Chong, Jane A. Foster, Tie‐yuan Zhang, Jason P. Lerch, Brian J. Nieman, Mark R. Palmert   +7 more
wiley   +1 more source

Stromal fibroblastic mutant Trp53 promotes mammary tumor development via enhanced secretion of paracrine factors. [PDF]

NPJ Breast Cancer
Liu B, Xiong S, Williams-Villalobo A, Chau G, Qi Y, Chen H, Johnson C, Chachad D, McDaniel J, Su X, El-Naggar AK, Lozano G, Zhang Y.   +12 more
europepmc   +1 more source

Statins in Breast Cancer Therapy: Mechanistic Insights and Emerging Evidence

Cancer Innovation, Volume 5, Issue 1, February 2026.
Statins, particularly simvastatin, demonstrate potential as adjuvant agents in breast cancer treatment by disrupting tumour cell signalling and survival pathways. This review highlights emerging evidence supporting their repurposing for improved outcomes, especially in aggressive breast cancer subtypes.
Rohina Alim, H. M. Kasuni Akalanka
wiley   +1 more source

Carcinogenicity of atrazine, alachlor, and vinclozolin. [PDF]

Lancet Oncol
Cattley RC, De Roos AJ, Mandrioli D, Pearce N, Pronk A, Soshilov A, Abarikwu SO, Baldi I, Barr DB, Freeman LEB, Bortoli S, Connolly A, Dalvie MA, Ferreira MJ, Genter MB, Le Hégarat L, Lorenzetti S, McLaughlin JR, Møller P, Montagner CC, Silveira HCS, Toyoda T, Volle DH, Benbrahim-Tallaa L, de Conti A, Facchin C, Kunzmann AT, Madia F, Pasqual E, Aix ML, Deng X, Dongoran RA, Olanipekun MT, Suonio E, Viegas S, Mattock H, Wedekind R, Schubauer-Berigan MK.   +37 more
europepmc   +1 more source

Loss of hormone receptor expression in breast tissue following pre‐surgical therapy with an SERD

Histopathology, EarlyView.
Francesco de Napoli, Bethania Fernandes, Silvia Uccella, Margherita D'Arezzo, Martina Iuzzolino, Luca Di Tommaso   +5 more
wiley   +1 more source