Results 121 to 130 of about 88,076 (273)
The retrovirus mouse mammary tumor virus is present in mouse strains with a high incidence of mammary tumors as a causative agent. It is produced mainly in the mammary glands of sexually mature females and is milk-transmitted to newborns. The fate of the
BEVILACQUA, GENEROSO +2 more
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White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang +12 more
wiley +1 more source
B and T cells are required for mouse mammary tumor virus spread within the mammary gland.
Mouse mammary tumor virus (MMTV) is an infectious retrovirus transmitted through milk from mother to newborns. MMTV encodes a superantigen (SAg) whose activity is indispensable for the virus life cycle, since a genetically engineered virus with a ...
Golovkina, T V, Ross, S R, Dudley, J P
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Dmp1α inhibits HER2/neu-induced mammary tumorigenesis.
Our recent study shows a pivotal role of Dmp1 in quenching hyperproliferative signals from HER2 to the Arf-p53 pathway as a safety mechanism to prevent breast carcinogenesis.
Elizabeth A Fry +5 more
doaj +1 more source
Intra‐tumoral oxygen deprivation (hypoxia) promotes the activation of hypoxia‐inducible factors (HIFs) that orchestrate the transcriptional adaptation of cancer cells to hypoxia. Hypoxia is prevalent in hepatocellular carcinoma (HCC), a cancer type with limited therapeutic options.
Ioanna‐Maria Gkotinakou +6 more
wiley +1 more source
A Novel Mechanism of Resistance to Mouse Mammary Tumor Virus Infection
Exogenous mouse mammary tumor virus (MMTV) is carried from the gut of suckling pups to the mammary glands by lymphocytes and induces mammary gland tumors. MMTV-induced tumor incidence in inbred mice of different strains ranges from 0 to as high as 100%
Tatyana V. Golovkina, Golovkina, T V
core +1 more source
Mouse mammary tumor virus (MMTV) infects both lymphoid tissue and lactating mammary gland during its infectious cycle, but some endogenous MMTVs are transcribed only in lymphoid cells.
Piazzon, I +6 more
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Titrations of various mouse mammary tumor viruses in different mouse strains
SUMMARY-Milks from the high-mammary-tumor mouse strains, A, BALB/cfC3H, Rill, and C3H were titrated for infectivity in low-mammary-tumor strains C57BL, BALB/c, Af, and Rlllf.
Charney, J +5 more
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The Role Of Mouse Mammary Tumor Virus In The Induction And Progression Of Mouse Mammary Tumors [PDF]
Mouse mammary tumor virus (MMTV) is a retrovirus which causes mammary tumors in many strains of mice. An essential part of the viral life cycle involves the integration of a double-stranded DNA provirus into the host cell genome. Tumorigenesis is thought to be mediated by such integrated proviruses.;Restriction endonuclease analysis of the DNA from a ...
openaire
Bl-MaTU/A1 mouse mammary tumor cells, derived from a C57B1/10 mammary adenocarcinoma induced by dimethylbenzanthracene and mammotropic hormones, express virus particles and proteins related to mouse mammary tumor virus (MMTV).
Juraj Svec +5 more
core +1 more source

