Results 211 to 220 of about 88,076 (273)

Proteomic signatures of adipocyte recruitment in breast cancer. [PDF]

open access: yesEndocr Relat Cancer
Argyris DG   +10 more
europepmc   +1 more source

Superantigens of Mouse Mammary Tumor Virus

open access: yesAnnual Review of Immunology, 1995
Superantigens (SAgs) are proteins of microbial origin that bind to major histocompatibility complex (MHC) class II molecules and stimulate T cells via interaction with the V beta domain of the T cell receptor (TCR). Mouse mammary tumor virus (MMTV) is a milk-transmitted type B retrovirus that encodes a SAg in its 3' long terminal repeat.
Acha-Orbea H, MacDonald HR
core   +5 more sources

Involvement of a mouse mammary tumor virus (MMTV) homologue in human breast cancer: Evidence for, against and possible causes of controversies

Microbial Pathogenesis, 2019
Breast cancer (BC) is a complex and heterogeneous disease whose evolution depends on the tumor-host interaction. This type of cancer occurs when the mammary cells begin to grow wildly and become able to invade nearby tissues and/or promote metastases ...
Marla Karine Amarante   +2 more
exaly   +2 more sources

Mouse mammary tumor virus and mammary tumorigenesis in wild mice

Pathology International, 1996
The current knowledge of the distribution of the mouse mammary tumor virus (MMTV) proviral genomes and the mechanism of mammary tumorigenesis by MMTV in mice, with the main emphasis on Asian feral mice, is reviewed. The relevant earlier discoveries on the mode of MMTV transmission are summarized to provide an outline of the biology of MMTV.
Shunsuke Imai
exaly   +3 more sources

Biology of mouse mammary tumor virus (MMTV)

Cancer Letters, 1995
Mouse mammary tumor viruses (MMTV) replicate in the mammary gland, appear as infectious particles in mother's milk and invade the sucking pups from the intestinal tract. The immune system is essential for MMTV in the gut to reach the mammary gland. These properties make the life cycle of MMTV unique.
Akio Matsuzawa   +2 more
exaly   +3 more sources

High prevalence of mouse mammary tumor virus-like gene sequences in breast cancer samples of Iranian women

open access: yesNucleosides, Nucleotides and Nucleic Acids, 2017
Mouse mammary tumor virus (MMTV) is considered to be responsible for breast tumor development in mice. In several instances sequences homologous to the genome of this virus have been reported in human breast cancer samples. Here we aimed to evaluate MMTV
Najma Farahani   +2 more
exaly   +2 more sources

Mouse Mammary Tumor Virus and the Immune System

Immunologic Research, 2003
Mouse mammary tumor virus (MMTV) is a nonacute transforming retrovirus that causes mammary tumors in susceptible strains of mice. Upon milk-borne transmission, B cells in the gut become infected and subsequently present a virus-encoded superantigen to cognate T cells.
Jennifer, Czarneski   +2 more
openaire   +2 more sources

The polypeptide composition of mouse mammary tumor virus

Virology, 1974
Abstract The polypeptide composition of mouse mammary tumor virus isolated from several strains of mice, has been examined by polyacrylamide gel electrophoresis. Gel Patterns, as revealed by staining and 14 C amino acid labelling, showed 10 polypeptide species reproducibly associated with the virus.
C, Dickson, J J, Skehel
openaire   +2 more sources

Antisense Downregulation of a Mouse Mammary Tumor Virus Activated Protooncogene in Mouse Mammary Tumor Cells Reverses the Malignant Phenotype

open access: yesVirology, 1999
Activation of the protooncogeneWnt-1 by insertion of the mouse mammary tumor virus (MMTV) is known to cause mammary tumors in mice.Wnt-1 expression in mammary glands has been postulated to confer direct local growth stimulation of mammary epithelial ...
Jackie Papkoff   +2 more
exaly   +2 more sources

Surface structure of mouse mammary tumor virus

Virology, 1974
Abstract The structure of the envelope of mouse mammary tumor virus (MuMTV) was studied by using negative stain, thin sections and freeze-drying-shadowing. The surface of the viral membrane was found to contain a reticular structure composed mainly of hexagons and occasional pentagons. The spacing between the nearest corners was about 74 A. The viral
Sarkar, N H, Moore, D H
openaire   +2 more sources

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