Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8a1 and human ch13q34 [PDF]
Serial analysis of gene expression from aggressive mammary tumors derived from transplantable p53 null mouse mammary outgrowth lines revealed significant up-regulation of Tfdp1 (transcription factor Dp1), Lamp1 (lysosomal membrane glycoprotein 1) and ...
Abba, Martín Carlos +8 more
core +1 more source
Histopathological Assessment of Testicular Tissues from Mice with Xenografted Human Triple-Negative Breast Cancer [PDF]
Introduction: Mammary tumors are a common cancer in human but little is known about their histopathological characteristics and effects on other organs.
Armaghan Davoudi +10 more
doaj +1 more source
Mammary gland tumors in a male Cocker Spaniel
Background Mammary gland tumors are the most common tumors in sexually intact female dogs; however, they are rare in male dogs. This study was conducted to investigate the relationship between sexual hormones and mammary gland tumors in a male dog.
Soon-Chan Kwon +8 more
doaj +1 more source
Cannabinoid receptor CB2 drives HER2 pro-oncogenic signaling in breast cancer [PDF]
Pharmacological activation of cannabinoid receptors elicits antitumoral responses in different models of cancer. However, the biological role of these receptors in tumor physio-pathology is still unknown.
Alkatout, Ibrahim +31 more
core +1 more source
Prognostic Significance of Canine Mammary Tumor Histologic Subtypes: An Observational Cohort Study of 229 Cases [PDF]
Histopathology is considered the gold standard diagnostic method for canine mammary tumors. In 2011, a new histologic classification for canine mammary tumors was proposed.
Berlato, Davide +3 more
core +1 more source
Detection of mutations within exons 4 to 8 of the p53 tumor suppressor gene in canine mammary glands
Fifteen female canines with mammary tumors and 6 normal females were used to study mutations in exons 4 to 8 of the p53 gene. DNA samples from the tumors, respective adjacent normal mammary tissue and mammary glands from healthy animals were sequenced ...
D.M.B. Souza +7 more
doaj +1 more source
Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells [PDF]
Indexación: Web of Science; Scopus.Cyclooxygenase (COX)-2 expression is positively correlated with malignant features in canine mammary carcinomas. Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit COX activity and may therefore possess anticancer ...
Arias, J.I. +3 more
core +1 more source
Alterations in the mammary gland and tumor microenvironment of formerly obese mice
Background Obesity is a risk factor for breast cancer, and women with obesity that develop breast cancer have a worsened prognosis. Within the mammary gland, obesity causes chronic, macrophage-driven inflammation and adipose tissue fibrosis.
Genevra Kuziel +5 more
doaj +1 more source
Estrogen and progesterone induce persistent increases in p53-dependent apoptosis and suppress mammary tumors in BALB/c-Trp53+/- mice [PDF]
INTRODUCTION Treatment with estrogen and progesterone (E+P) mimics the protective effect of parity on mammary tumors in rodents and depends upon the activity of p53.
Blackburn, Anneke C +4 more
core +1 more source
Pleiotropic functions of the tumor- and metastasis-suppressing Matrix Metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice [PDF]
Matrix metalloproteinase-8 (MMP-8; neutrophil collagenase) is an important regulator of innate immunity which has onco-suppressive actions in numerous tumor ...
A Dufour +62 more
core +3 more sources

