Epidemiological study of canine mammary tumors: age, breed, size and malignancy
Austral Journal of Veterinary Sciences, 2018 A retrospective study was carried out on 858 female canine patients who were attended at the Surgery Service of the Clinical Veterinary Hospital of the University of Extremadura (Spain), during a period of 5 years (2008-2012).
Nieves Pastor +5 more
doaj +1 more source
Alterations in the mammary gland and tumor microenvironment of formerly obese mice
BMC Cancer, 2023 Background Obesity is a risk factor for breast cancer, and women with obesity that develop breast cancer have a worsened prognosis. Within the mammary gland, obesity causes chronic, macrophage-driven inflammation and adipose tissue fibrosis.
Genevra Kuziel +5 more
doaj +1 more source
ß1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli [PDF]
, 2005 Integrins are cell adhesion receptors which mediate interactions between the extracellular matrix and the actin cytoskeleton. They are heterodimers composed of α and β subunits. As adhesion receptors, integrins are important for cell-cell and cell-matrix
Li, Na
core +1 more source
AnimalsCompared to the number of studies on the neoplasms of laboratory rodents, fewer studies have focused on spontaneous neoplasms in pet rodents. Notably, the mouse mammary tumor virus (MMTV) is associated with mammary tumors in rodents.
Ya-Mei Chen, Jia-Ling Wu, Wei-Hao Lin
doaj +1 more source
Epidemiological Study of Mammary Tumors in Female Dogs Diagnosed during the Period 2002-2012: A Growing Animal Health Problem. [PDF]
PLoS ONE, 2015 Epidemiological studies enable us to analyze disease behavior, define risk factors and establish fundamental prognostic criteria, with the purpose of studying different types of diseases.
Yaritza Salas +3 more
doaj +1 more source
Prognostic impact of alterations in E-cadherin and P-cadherin expression in canine mammary tumors
Brazilian Journal of Veterinary Pathology, 2021 Expression of cadherins has been correlated to the development and aggressiveness of epithelial neoplasms, however, in canine mammary tumors, their significance prognostic is uncertain.
Luciana R. Gomes +5 more
doaj +1 more source
Folic acid supplementation promotes mammary tumor progression in a rat model.
PLoS ONE, 2014 Folic acid supplementation may prevent the development of cancer in normal tissues but may promote the progression of established (pre)neoplastic lesions.
Shaidah Deghan Manshadi +6 more
doaj +1 more source
Genetic mechanisms in Apc-mediated mammary tumorigenesis. [PDF]
PLoS Genetics, 2009 Many components of Wnt/beta-catenin signaling pathway also play critical roles in mammary tumor development, yet the role of the tumor suppressor gene APC (adenomatous polyposis coli) in breast oncongenesis is unclear.
Mari Kuraguchi +4 more
doaj +1 more source
Identifying the Risk Factors for Malignant Mammary Tumors in Dogs: A Retrospective Study
Veterinary Sciences, 2023 Mammary cancer is one of the main causes of death in female dogs worldwide, considering that many risk factors are involved in its development. This study aimed to elucidate the relationship between epidemiological and clinical risk factors with the ...
Elis Maressa Gonçalves da Silva +2 more
doaj +1 more source
Analysis of metabolites from mammary tumors.
, 2013 Mammary glands from WT mice and tumors from STK11−/−/NIC mice were excised and analyzed for A, expression of LDH, and PDH glycolytic enzymes by western blot analysis.
Patricia Colp (381288) +3 more
core +1 more source