Results 101 to 110 of about 9,219,877 (345)

Organizational and economic algorithms of digital audit and digital controlling in the management system of large industrial enterprises

open access: yesПутеводитель предпринимателя, 2020
Goals. Based on the analysis of literature sources, as well as international experience in the development of digital audit and digital controlling technologies, to study organizational and economic algorithms of digital audit and digital controlling in ...
M. V. Belyaeva
doaj  

The United States and CGIAR: Five "WINS" from collaboration [PDF]

open access: yes, 2017
The United States investment in CGIAR research is a win-win proposition for the US and developing ...
CGIAR System Management Office
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Building blocks for enhancing personnel performance: activities, best practices and lessons learned from Ethiopia

open access: yesJournal of Pharmaceutical Policy and Practice, 2014
Daniel Taddesse   +3 more
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

2015 CGIAR Intellectual Assets report [PDF]

open access: yes, 2016
This CGIAR Intellectual Assets (IA) Report covers the calendar year 2015 and corresponds to the fourth reporting cycle under the CGIAR Principles on the Management of Intellectual Assets (CGIAR IA Principles). It was developed by the CGIAR Consortium, in
CGIAR System Management Office
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy