Results 51 to 60 of about 1,000 (213)

The Effect of α-Mangostin on the Pharmacokinetic Profile of Tofacitinib in Rats Both In Vitro and In Vivo. [PDF]

Biopharm Drug Dispos
α‐mangostin (α‐MG) significantly affected tofacitinib metabolism by competing for the same site in CYP3A4. Co‐administration of these two medicines poses a potential herb–drug interaction. ABSTRACT This study investigated the effects of α‐mangostin (α‐MG) on the pharmacokinetics of tofacitinib in vitro and in vivo, aiming to recommend its appropriate ...
Yao J, Lu Z, Zhou Q, Mamun AA, Shi Y, Wang S, Yao Y.   +6 more
europepmc   +2 more sources

Antimicrobial Effects of Garcinia Mangostana on Cariogenic Microorganisms [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Garcinia mangostana commonly called as Mangosteen fruit has been used as an antibacterial agent since age old times. The mangosteen pericarp has proven to have antibacterial effect, but the effect of the same on cariogenic organisms has ...
Sunitha Janardhanan, Jaideep Mahendra, A. S. Smiline Girija, Little Mahendra, Vijayashree Priyadharsini   +4 more
doaj   +1 more source

The efficacy of adjunctive <i>Garcinia mangostana</i> Linn. (mangosteen) pericarp extract for bipolar depression: 24-week randomised controlled trial. [PDF]

Br J Psychiatry
Background: Bipolar depression remains difficult to treat, and people often experience ongoing residual symptoms, decreased functioning and impaired quality of life.
Dean OM, Cotton SM, Ashton MM, Turner A, Saunders L, Ng CH, Hopwood M, Dodd S, Khoo JP, Walker AJ, Chatterton ML, Kavanagh BE, Nadjidai SE, Lo Monaco SL, Harvey BH, Malhi GS, Brown E, Skvarc DR, Diao D, Jacka FN, Sarris J, Dowling NL, Berk M.   +22 more
europepmc   +2 more sources

Optimization of Subcritical Ethanol Extraction for Xanthone from Mangosteen Pericarp [PDF]

International Journal of Chemical Engineering and Applications, 2015
 Abstract—Mangosteen pericarp has been used for long time as traditional medicine. One of main active ingredient in mangosteen pericarp is xanthone. Xanthone has remarkable effects on cardiovascular, antiviral, and anti-inflammatory. Subcritical ethanol extraction (Sc-ethanol) was employed to extract xanthone from dried mangosteen pericarp and ...
Nuttawan Yoswathana, Eshtiaghi M. N
openaire   +1 more source

The role of different natural organic acids in postharvest fruit quality management and its mechanism

Food Frontiers, Volume 4, Issue 3, Page 1127-1143, September 2023., 2023
The present work reviews recent applications of natural organic acids in postharvest fruits quality management including the effect on delaying senescence, alleviating chilling injury, controlling disease, and inhibiting browning. In addition, the potential biochemical mechanisms of the applications of natural organic acids in improving postharvest ...
Wanli Zhang, Yueming Jiang, Zhengke Zhang   +2 more
wiley   +1 more source

α‐Mangostin induces oxidative damage, mitochondrial dysfunction, and apoptosis in a triple‐negative breast cancer model

Phytotherapy Research, Volume 37, Issue 8, Page 3394-3407, August 2023., 2023
Abstract Triple‐negative breast cancer (TNBC) does not express estrogen receptor, progesterone receptor, and human epidermal growth factor receptor; therefore, TNBC lacks targeted therapy, and chemotherapy is the only available treatment for this illness but causes side effects.
Alfredo Cruz‐Gregorio, Ana Karina Aranda‐Rivera, Omar Emiliano Aparicio‐Trejo, Omar Noel Medina‐Campos, Edda Sciutto, Gladis Fragoso, José Pedraza‐Chaverri   +6 more
wiley   +1 more source

Effects of Mangosteen Pericarp Extracts Against Mammary Cancer [PDF]

Alternative & Integrative Medicine, 2013
The pericarp of the mangosteen fruit, Garcinia mangostana Linn, has a long history of use as a medicinal plant in Southeast Asia. The actions of mangosteen extracts have been scientifically supported and it has become a popular natural health-promoting dietary supplement.
openaire   +1 more source

ACTIVITY OF PERICARP EXTRACT OF MANGOSTEEN AGAINST ORAL STREPTOCOCCI

Dentika: Dental Journal, 2017
The increasing prevalence of dental caries is still as a major world health problem. Caries is the direct result of acid production by cariogenic oral pathogens, especially Streptococcus mutans. New and better antimicrobial agents active against cariogenic bacteria with minimal side effects on the oral tissues are much needed, especially natural agents
Dewi Nurul Mustaqimah, Josh Erry HW
openaire   +1 more source

Isolation of a High Antioxidant Non-Toxic Polar Fraction from Garcinia mangostana Fruit Pericarp by Reverse Phase Column Chromatography

Jurnal Kimia Sains dan Aplikasi, 2021
The crude polar extract of mangosteen fruit pericarp not only has a moderate antioxidant activity of (55±4 μg/mL) but also has high cytotoxicity (16±0.5 μg/mL).
Wahyuningsih Wahyuningsih, Miranti Miranti, Hilwan Yuda Teruna, Titania Tjandrawati Nugroho   +3 more
doaj   +1 more source

Potency of Mangosteen Pericarp Extract to Inhibit 38-kDa and Ag85 Protein Secretion by Mycobacterium tuberculosis H37Rv: Mangosteen pericarp inhibit Tuberculosis Protein secretion

, 2020
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. The α-mangostin in mangosteen pericarp extract can inhibit M. tuberculosis growth.
Maula, Eka Riza, Yurina, Valentina, Nurhidayati, Dwi Yuni   +2 more
core   +1 more source