Results 91 to 100 of about 37,714 (305)
Diplopia Due to Congenital Myasthenic Syndrome Mimics Divergence Insufficiency
, 2023 Congenital myasthenic syndromes (CMS) are a genotypically and phenotypically heterogeneous group of neuromuscular disorders from the impaired neuromuscular transmission.
Yan Yan, MD, PhD
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Cognitive dysfunction in hereditary spastic paraplegias and other motor neuron disorders
Dementia & NeuropsychologiaHereditary spastic paraplegia (HSP) is a diverse group of single-gene disorders that share the predominant clinical feature of progressive lower limb spasticity and weakness.
Ingrid Faber +2 more
doaj +1 more source
The Gagatli swarm of weak earthquakes - seismo activity manifestation of the Andean fault
Российский сейсмологический журнал [Russian Journal of Seismology], 2019 The swarm of more than a hundred weak earthquakes, the bulk of which occurred in the second decade of January 2019, was recorded at the end of 2018 and at the beginning of 2019 in the area of the western borders of the Dagestan salient. Refinement of the position of the epicenters of the swarm events by the method of double differences showed their ...
Irina Gabsatarova +3 more
openaire +1 more source
, 2018 Juvenile Dermatomyositis is the most common inflammatory myositis in children, distinguished by proximal muscle weakness, a characteristic rash and Gottron\u27s papules.
Pritesh Ruparelia +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2021 Case Presentation A 42-year-old female with a past medical history of schizoaffective disorder recently discontinued on multiple psychiatric medications, stable HIV, and hypothyroidism presented with a chief complaint of diffuse extremity weakness and ...
Paiva, Cody, Clark, Brinton
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Same or opposite? association of head-movement weakness with limb paresis in stroke
, 2011 OBJECTIVES: The precise innervation of the sternocleidomastoids is uncertain. Of clinical interest is whether a unilateral hemispheric lesion leads to an ispilateral or contralateral sternocleidomastoid weakness. METHODS: Sternocleidomastoid strength was
Spengos, K. +5 more
core
, 2011 Guillain-Barré syndrome (GBS) is the eponym used to describe acute inflammatory polyradiculoneuropathies, which manifest with weakness and diminished reflexes. Although the classic form of GBS is considered to be an ascending demyelinating polyneuropathy,
Kahn, D. Ethan +5 more
core +1 more source