Results 301 to 310 of about 89,044 (334)
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Mannose-Binding Lectins in Cerebrum Development
2003The nervous system is so complex that it is not ordinarily considered as an interesting model for studying cellular mechanisms. However, its morphology (at least in some well-defined areas) provides essential information because cells are polarised: cell body, axons and dendrites can be easily identified in vivo, an essential property when studies are ...
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Anti-microbial activities of mannose-binding lectin
Biochemical Society Transactions, 2003Mannose-binding lectin (MBL; also known as mannan-binding lectin) is involved in first-line defence by binding to bacteria, viruses, protozoa and helminths through a pattern-recognition mode of detection and then initiating a range of host responses. Currently, we have been unable to extrapolate from what we know of the biochemistry of MBL binding to ...
Malcolm W. Turner, D.L. Jack
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Mannose-binding lectin genetics: from A to Z
Biochemical Society Transactions, 2008MBL (mannose-binding lectin) is primarily a liver-derived collagen-like serum protein. It binds sugar structures on micro-organisms and on dying host cells and is one of the four known mediators that initiate activation of the complement system via the lectin pathway.
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Mannose‐binding lectin gene polymorphisms in relation to periodontitis
Journal of Clinical Periodontology, 2008AbstractAim: To investigate the correlation of six functional polymorphisms in the MBL gene with MBL plasma levels in relation to periodontitis.Material and Methods: A total of 92 periodontitis patients and 70 controls, all of Caucasian origin, were included.
Louropoulou, A.+5 more
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The role of mannose-binding lectin in health and disease
Molecular Immunology, 2003Mannose-binding lectin (MBL) is a pattern recognition molecule of the innate immune system. It belongs to the collectin family of proteins in which lectin (carbohydrate-recognition) domains are found in association with collagenous structures. In man, these proteins include serum MBL, lung surfactant protein A (SP-A) and lung surfactant protein D (SP-D)
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Ureaplasma urealyticum binds mannose-binding lectin
Experimental and Molecular Pathology, 2004Mannose-binding C-type lectin (MBL) is an important component of innate immunity in mammals. Mannose-binding lectin (MBL), an acute phase protein, acts as an opsonin for phagocytosis and also activates the mannan-binding lectin complement pathway. It may play a particularly significant role during infancy before adequate specific protection can be ...
Dennis T Crouse+3 more
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Mannose‐binding lectin: biology and clinical implications
Internal Medicine Journal, 2005Abstract The innate host defence molecule mannose‐binding lectin (MBL) has attracted great interest as a potential candidate for passive immunotherapy to prevent infection. MBL is a multimeric lectin that recognizes a wide array of pathogens independently of specific antibody, and initiates the lectin pathway of complement activation.
Daniel L. Worthley+2 more
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Application of Lectin Microarrays for Biomarker Discovery
ChemistryOpen, 2020Airong Qian, Airong Qian
exaly