Results 81 to 90 of about 181,826 (246)

Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies

Nature Communications, 2015
The envelope spike of HIV-1 employs a ‘glycan shield’ to protect itself from antibody-mediated neutralization. Paradoxically, however, potent broadly neutralizing antibodies (bnAbs) that target this shield have been isolated.
Laura K. Pritchard, D. Spencer, L. Royle, Camille Bonomelli, Gemma E. Seabright, Anna-Janina Behrens, Daniel W. Kulp, Sergey Menis, S. A. Krumm, D. Dunlop, D. J. Crispin, T. Bowden, Christopher N. Scanlan, A. Ward, W. Schief, W. Schief, K. Doores, M. Crispin   +17 more
semanticscholar   +1 more source

Mannose receptor-mediated delivery of moss-made α-galactosidase A efficiently corrects enzyme deficiency in Fabry mice

Journal of Inherited Metabolic Disease, 2015
Enzyme replacement therapy (ERT) is an effective treatment for several lysosomal storage disorders (LSDs). Intravenously infused enzymes are taken up by tissues through either the mannose 6-phosphate receptor (M6PR) or the mannose receptor (MR).
Jinsong Shen, A. Busch, Taniqua S. Day, Xing‐Li Meng, Chun I Yu, Paulina Dabrowska-Schlepp, Benjamin Fode, Holger Niederkrüger, S. Forni, Shuyuan Chen, R. Schiffmann, T. Frischmuth, A. Schaaf   +12 more
semanticscholar   +1 more source

Mannose metabolism normalizes gut homeostasis by blocking the TNF-α-mediated proinflammatory circuit

Cellular & Molecular Immunology, 2022
P. Xiao, Ziwei Hu, Jiaheng Lang, Tianyuan Pan, R. T. Mertens, Huilun Zhang, Ke Guo, Manlu Shen, Hongqiang Cheng, Xue Zhang, Q. Cao, Yuehai Ke   +11 more
semanticscholar   +1 more source

Chemical Analysis and Antioxidant Capacity of the Stages of Lignocellulosic Ethanol Production from Amazonian Fruit Industrial Waste

Fermentation
: The production of ethanol from wastes resulting from the process of growing Amazonian fruit is a little-explored approach, in which unknown chemical compounds are released with potential for industrial application.
Gabriela Vieira Pantoja, Johnatt Allan Rocha de Oliveira   +1 more
doaj   +1 more source

O-Mannosylation of Proteins Enables Histoplasma Yeast Survival at Mammalian Body Temperatures

mBio, 2018
The ability to grow at mammalian body temperatures is critical for pathogen infection of humans. For the thermally dimorphic fungal pathogen Histoplasma capsulatum, elevated temperature is required for differentiation of mycelia or conidia into yeast ...
Andrew L. Garfoot, Kristie D. Goughenour, Marcel Wüthrich, Murugesan V. S. Rajaram, Larry S. Schlesinger, Bruce S. Klein, Chad A. Rappleye   +6 more
doaj   +1 more source

The alcoholic ferment of yeast-juice. Part IV.—The fermentation of glucose, mannose, and fructose by yeast-juice [PDF]

, 1909
Arthur Harden, William J. Young
openalex   +1 more source

Mannose enhances intestinal immune barrier function and dextran sulfate sodium salt-induced colitis in mice by regulating intestinal microbiota

Frontiers in Immunology
BackgroundInflammatory bowel disease (IBD) greatly affects human quality of life. Mannose has been reported to be used to treat IBD, but the mechanism is currently unknown.MethodsC57/BL mice were used as research subjects, and the mouse acute colitis ...
Yi Yang, Qiming Ma, Qingyu Wang, Lifeng Zhao, Hengshan Liu, Yanjun Chen   +5 more
doaj   +1 more source

Substrate Promiscuity of N-Acetylhexosamine 1-Kinases

Molecules, 2011
N-Acetylhexosamine 1-kinase (NahK) catalyzes the direct addition of a phosphate from adenosine 5'-triphosphate (ATP) to the anomeric position of N-acetylhexosamine and shows similar activity towards N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (
Hongzhi Cao, Li Cai, Xi Chen, Peng George Wang, Vinod Kumar Tiwari, Jingyao Qu, Vireak Thon, Kam Lau, Yi Chen, Hai Yu, Yanhong Li   +10 more
doaj   +1 more source

THE CONFIGURATION OF GLYCOSIDIC LINKAGES IN OLIGOSACCHARIDES: III. O-α-D-MANNOPYRANOSYL-(1 → 2)-O-α-D-MANNOPYRANOSYL-(1 → 2)-D-MANNOSE [PDF]

, 1957
P. A. J. Gorin, A. S. Perlin
openalex   +1 more source

Cell-Free Enzymatic Conversion of Spent Coffee Grounds Into the Platform Chemical Lactic Acid

Frontiers in Bioengineering and Biotechnology, 2019
The coffee industry produces over 10 billion kg beans per year and generates high amounts of different waste products. Spent coffee grounds (SCG) are an industrially underutilized waste resource, which is rich in the polysaccharide galactomannan, a ...
Dominik Kopp, Robert D. Willows, Anwar Sunna, Anwar Sunna   +3 more
doaj   +1 more source