Targeting the Mannose Receptor with Functionalized Fucoidan/Chitosan Nanoparticles Triggers the Classical Activation of Macrophages. [PDF]
Int J Mol Sci, 2023 Serrasqueiro F +3 more
europepmc +1 more source
Mechanism and role of regulated cell death in tumor immunity and immunotherapy
Cancer Communications, EarlyView.Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu +4 more
wiley +1 more source
Reactivity of Carbohydrate Phosphodiesters, Potential Targets of Antibacterial Agents
Chemistry &Biodiversity, EarlyView.A simple carbohydrate phosphodiester model was synthesized to compare the reactivity of phosphodiester bonds within carbohydrates and RNA. ABSTRACT While monosaccharide units in bacterial carbohydrates may be linked with phosphodiester bonds, human carbohydrates exclusively contain glycosidic linkages.
Eero Sillanpää +2 more
wiley +1 more source
Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases
ChemistryEurope, EarlyView.Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang +7 more
wiley +1 more source
A pH‐Responsive Synthetic Receptor for Switchable Binding of Carbohydrates
ChemPlusChem, EarlyView.A diaminocarbazole macrocyclic receptor, designed for disaccharide recognition in water, exhibits distinct binding properties under alkaline versus neutral pH conditions. Carbohydrates are selectively recognized under alkaline conditions, whereas release of the bound guest occurs at physiological pH, effectively behaving as a pH‐switchable carbohydrate
Francesco Milanesi +4 more
wiley +1 more source
Biomimetic System Based on Reconstituted Macrophage Membranes for Analyzing and Selection of Higher-Affinity Ligands Specific to Mannose Receptor to Develop the Macrophage-Focused Medicines. [PDF]
Biomedicines, 2023 Zlotnikov ID, Kudryashova EV.
europepmc +1 more source
Conversion of G-protein specificity of insulin-like growth factor II/mannose 6-phosphate receptor by exchanging of a short region with beta-adrenergic receptor. [PDF]
, 1993 Kyôko Takahashi +8 more
openalex +1 more source
Learning Strategies from Nature's Blueprint to Cyclic Carbonate Synthesis
ChemSusChem, Volume 18, Issue 6, March 15, 2025.The development of sustainable synthetic methods for cyclic carbonates draws inspiration from nature, focusing on eco‐friendly processes and renewable resources like CO2 and biomass. This review explore various CO2 activation mechanisms, green chemistry principles, and green catalysts.
Erika Saccullo +4 more
wiley +1 more source
Sulfation at Glycopolymer Side Chains Switches Activity at the Macrophage Mannose Receptor (CD206) In Vitro and In Vivo. [PDF]
J Am Chem Soc, 2022 Mastrotto F +5 more
europepmc +1 more source