Results 141 to 150 of about 2,479,436 (371)
Loss of ATF3 exacerbates liver damage through the activation of mTOR/p70S6K/ HIF-1α signaling pathway in liver inflammatory injury. [PDF]
, 2018 Activating transcription factor 3 (ATF3) is a stress-induced transcription factor that plays important roles in regulating immune and metabolic homeostasis.
Jiang, Bin +9 more
core +2 more sources
Advanced Science, EarlyView.Well‐defined and synthetic mannose‐capped arabinomannan 101‐mer from Mycobacterium tuberculosis cell wall was identified as a potent influenza vaccine adjuvant, boosting the antibody response, realizing full protection and showing excellent safety. ABSTRACT Many natural bacterial components as adjuvants can activate the host immune system, but the ...
Yu‐Fang Zhang +5 more
wiley +1 more source
Postepy higieny i medycyny doswiadczalnej, 2002 The mannose receptor (MR) is a calcium-dependent C-type lectin that is expressed on some macrophages, immature dendritic cells, endothelial, and epithelial cells. The most important feature of MR is the capability to distinguish self from non-self molecules through the interaction of multiple CRDs.
openaire +1 more source
Advanced Science, EarlyView.SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv +16 more
wiley +1 more source
Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders
Advanced Science, EarlyView.Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li +7 more
wiley +1 more source
Molecules, 2017 Mannose-diester lauric diacid-cholesterol (Man-DLD-Chol), as a liposomal target ligand, was synthesized by lipase catalyzed in a non-aqueous medium.
Jing Chen +3 more
doaj +1 more source
Poria cocos as a Functional Food for Diabetes and Diabetes‐Related Foot Ulcers
AgriFood: Journal of Agricultural Products for Food, EarlyView.Poria cocos is known as an edible mushroom for food and medicine. Poria cocos and its terpenes and terpenoids serve as novel remedies to treat diabetes and its ulcers. Its mode of actions includes reduction of insulin resistance, starch digestion and inflammation as well as promotion of blood vessel formation. ABSTRACT Poria cocos is a medicinal fungus
Yi‐San Lee +3 more
wiley +1 more source
Toxins, 2018 Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by highly pruritic, erythematous, and eczematous skin plaques. We previously reported that phospholipase A2 (PLA2) derived from bee venom alleviates AD-like skin lesions induced ...
Dasom Shin, Won Choi, Hyunsu Bae
doaj +1 more source
Cation-Independent Mannose 6-Phosphate Receptor Deficiency Enhances β -Cell Susceptibility to Palmitate [PDF]
, 2018 Aaron C. Baldwin +7 more
openalex +1 more source
Lysosome sorting of β-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor
Nature Communications, 2014 The integral membrane protein LIMP-2 has been a paradigm for mannose 6-phosphate receptor (MPR) independent lysosomal targeting, binding to β-glucocerebrosidase (β-GCase) and directing it to the lysosome, before dissociating in the late-endosomal ...
Yuguang Zhao +4 more
semanticscholar +1 more source